Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   ODS73_RS09405 Genome accession   NZ_CP107038
Coordinates   1818127..1818786 (+) Length   219 a.a.
NCBI ID   WP_000565001.1    Uniprot ID   A0A0B7M7B9
Organism   Streptococcus pneumoniae strain BM6001     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1813127..1823786
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ODS73_RS09385 (ODS73_09375) - 1813764..1814660 (-) 897 WP_050198591.1 PEP phosphonomutase -
  ODS73_RS09390 (ODS73_09380) - 1814663..1815925 (-) 1263 WP_050311690.1 PTS sugar transporter subunit IIC -
  ODS73_RS09395 (ODS73_09385) - 1816205..1817383 (+) 1179 WP_050095799.1 ROK family transcriptional regulator -
  ODS73_RS09400 (ODS73_09390) - 1817611..1818057 (-) 447 WP_050084675.1 GNAT family N-acetyltransferase -
  ODS73_RS09405 (ODS73_09395) cclA/cilC 1818127..1818786 (+) 660 WP_000565001.1 A24 family peptidase Machinery gene
  ODS73_RS09410 (ODS73_09400) - 1818838..1819989 (-) 1152 WP_284060537.1 XRE family transcriptional regulator -
  ODS73_RS09415 (ODS73_09405) - 1820004..1820735 (-) 732 WP_000934017.1 hypothetical protein -
  ODS73_RS09420 (ODS73_09410) - 1820955..1821065 (+) 111 Protein_1875 prepilin peptidase -
  ODS73_RS09425 (ODS73_09415) trpA 1821037..1821813 (-) 777 WP_001127044.1 tryptophan synthase subunit alpha -
  ODS73_RS09430 (ODS73_09420) trpB 1821806..1823029 (-) 1224 WP_000331289.1 tryptophan synthase subunit beta -
  ODS73_RS09435 (ODS73_09425) - 1823007..1823606 (-) 600 WP_000169909.1 phosphoribosylanthranilate isomerase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24820.92 Da        Isoelectric Point: 7.2761

>NTDB_id=737564 ODS73_RS09405 WP_000565001.1 1818127..1818786(+) (cclA/cilC) [Streptococcus pneumoniae strain BM6001]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLG
LLFLLYSWELLSLGQVVLITAGLTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=737564 ODS73_RS09405 WP_000565001.1 1818127..1818786(+) (cclA/cilC) [Streptococcus pneumoniae strain BM6001]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCCCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAAGTTCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGTAT
ATACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGTGCAGGGGATTTCCTC
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTCTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7M7B9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus pneumoniae TIGR4

98.174

100

0.982
  cclA/cilC Streptococcus pneumoniae Rx1

96.804

100

0.968
  cclA/cilC Streptococcus pneumoniae D39

96.804

100

0.968
  cclA/cilC Streptococcus pneumoniae R6

96.804

100

0.968
  cclA/cilC Streptococcus mitis SK321

92.237

100

0.922
  cclA/cilC Streptococcus mitis NCTC 12261

87.215

100

0.872