Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   QA712_RS09670 Genome accession   NZ_CP121539
Coordinates   1806692..1808134 (-) Length   480 a.a.
NCBI ID   WP_047205663.1    Uniprot ID   -
Organism   Lactococcus lactis strain MA5     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1801692..1813134
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QA712_RS09645 (QA712_09645) nox 1801710..1803050 (+) 1341 WP_047205660.1 H2O-forming NADH oxidase -
  QA712_RS09650 (QA712_09650) - 1803140..1803529 (+) 390 WP_372757071.1 single-stranded DNA-binding protein -
  QA712_RS09655 (QA712_09655) groES 1803649..1803933 (+) 285 WP_003131589.1 co-chaperone GroES -
  QA712_RS09660 (QA712_09660) groL 1804021..1805649 (+) 1629 WP_372757073.1 chaperonin GroEL -
  QA712_RS09665 (QA712_09665) vicX 1805696..1806508 (-) 813 WP_003131583.1 MBL fold metallo-hydrolase Regulator
  QA712_RS09670 (QA712_09670) vicK 1806692..1808134 (-) 1443 WP_047205663.1 cell wall metabolism sensor histidine kinase WalK Regulator
  QA712_RS09675 (QA712_09675) yycF 1808127..1808828 (-) 702 WP_003131580.1 response regulator YycF -
  QA712_RS09680 (QA712_09680) tmk 1809006..1809641 (+) 636 WP_015425847.1 dTMP kinase -
  QA712_RS09685 (QA712_09685) - 1809774..1810634 (+) 861 WP_372757075.1 DNA polymerase III subunit delta' -
  QA712_RS09690 (QA712_09690) yaaT 1810686..1811468 (+) 783 WP_372757077.1 regulatory iron-sulfur-containing complex subunit RicT Regulator
  QA712_RS09695 (QA712_09695) yabA 1811461..1811787 (+) 327 WP_011675472.1 DNA replication initiation control protein YabA -
  QA712_RS09700 (QA712_09700) rsmI 1811787..1812662 (+) 876 WP_047205666.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
  QA712_RS09705 (QA712_09705) - 1812739..1812930 (-) 192 WP_003131566.1 hypothetical protein -

Sequence

Protein


Download         Length: 480 a.a.        Molecular weight: 54686.18 Da        Isoelectric Point: 4.5889

>NTDB_id=737336 QA712_RS09670 WP_047205663.1 1806692..1808134(-) (vicK) [Lactococcus lactis strain MA5]
MIKFFNSMIFKGVVAHLLLFVILFMSSFDYNFAHLSTFIGYYLFSLVFVLVFLNQQHRMIVNVSKQMNDIKNGYLNRDKL
PKGTSEINELYDEILKLGEDIVRTQNNLENQRNQLDSILAYMVDGVIATDRRGNIIMANKSALHYLNTDNDLLMQKNIVE
VLKIADQYNFYDLLEKEPEITIETHDAGNEPISLHIKFALFRRESGFISGIIAVLHDMTEQDKAERERRLFVSNVSHELR
TPLTSVKAYLEALEDGAIEDKETASSFINVSLTETNRMIRMISDLLTLSRMDQDRIVLNKEMINLIAFLDYQINRLDQIL
ETESNDLISSNFTLVRKYSEQPIWVEIDTDKIAQVIDNIIGNAIKYSPKGGTITISVEKRENDVLISISDQGMGIPKSDL
LKIFDRFYRVDNASRNSKVGGTGLGLSIVHDIVKIHGGTIFASSEGEGKGTTFSFTLPYSLEAADDWDDGTDEFEFEDNE

Nucleotide


Download         Length: 1443 bp        

>NTDB_id=737336 QA712_RS09670 WP_047205663.1 1806692..1808134(-) (vicK) [Lactococcus lactis strain MA5]
ATGATTAAATTTTTTAATTCAATGATTTTTAAAGGAGTAGTTGCACACCTACTTCTTTTTGTCATCCTTTTTATGAGCAG
TTTTGATTACAATTTTGCTCATTTAAGTACTTTTATTGGTTATTACTTATTTTCACTCGTCTTTGTTTTAGTCTTTCTCA
ATCAGCAACATCGCATGATTGTGAATGTTTCTAAACAGATGAATGACATAAAAAATGGCTATTTAAATCGTGATAAACTC
CCAAAAGGGACAAGTGAAATCAATGAATTATATGATGAAATTTTAAAACTCGGTGAAGATATTGTTCGCACGCAGAACAA
TCTTGAAAATCAGCGTAATCAATTAGATAGTATTCTCGCATATATGGTTGATGGCGTCATTGCCACCGACCGTCGTGGAA
ATATTATTATGGCCAATAAATCAGCTTTGCATTATTTGAATACAGATAATGATCTCTTGATGCAAAAAAATATTGTTGAA
GTTTTAAAAATTGCTGACCAATATAATTTTTATGATTTATTAGAAAAAGAACCTGAAATAACTATTGAGACACACGATGC
TGGGAATGAACCCATTTCGCTCCACATTAAATTTGCCCTCTTTCGTCGTGAATCTGGTTTCATCTCAGGAATTATTGCCG
TCTTACATGATATGACTGAACAAGACAAGGCCGAACGAGAGCGCCGTCTCTTTGTTTCCAATGTTTCTCATGAACTCCGA
ACTCCGCTCACCTCAGTAAAAGCCTACTTGGAAGCACTAGAAGACGGAGCCATTGAGGATAAAGAAACAGCTTCATCCTT
TATTAATGTTTCACTTACTGAAACTAATCGGATGATTCGAATGATTTCCGACCTTTTGACTTTATCAAGAATGGATCAAG
ACCGAATCGTTCTTAATAAAGAAATGATTAATTTAATTGCCTTCTTAGACTATCAAATTAACCGTTTAGACCAAATTTTA
GAAACCGAATCAAACGATTTAATCTCTTCTAATTTCACTCTAGTCAGAAAATACTCTGAACAGCCCATCTGGGTCGAAAT
TGATACCGATAAAATTGCTCAAGTCATTGACAATATCATCGGAAATGCAATTAAGTATTCACCTAAAGGTGGAACTATTA
CCATTTCCGTTGAAAAACGTGAAAATGACGTTCTAATCTCCATCAGTGACCAAGGAATGGGAATTCCAAAATCTGATTTA
CTTAAGATTTTTGACCGTTTCTACCGAGTTGATAATGCTTCAAGAAATTCAAAAGTTGGGGGAACAGGTTTAGGGCTCTC
TATTGTCCATGATATTGTTAAAATACATGGCGGAACAATTTTTGCAAGTTCTGAAGGAGAAGGAAAAGGAACGACCTTTA
GTTTCACTCTTCCCTATTCTTTAGAAGCCGCAGATGACTGGGATGATGGTACTGATGAGTTTGAATTTGAGGATAACGAA
TAA

Domains

Predicted by InterProScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(228-293)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(348-459)

PAS domain (PAS_9)

(124-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

51.559

86.875

0.448
  micB Streptococcus pneumoniae Cp1015

47.748

92.5

0.442