Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilA   Type   Machinery gene
Locus tag   ND436_RS11545 Genome accession   NZ_CP106918
Coordinates   2145950..2147203 (+) Length   417 a.a.
NCBI ID   WP_003687004.1    Uniprot ID   A0AB74EGQ8
Organism   Neisseria gonorrhoeae strain 9071     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2140950..2152203
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ND436_RS11525 (ND436_011525) - 2141701..2142702 (+) 1002 WP_003686999.1 thiamine ABC transporter substrate-binding protein -
  ND436_RS11530 (ND436_011530) - 2142796..2143644 (+) 849 WP_003687000.1 mechanosensitive ion channel family protein -
  ND436_RS11535 (ND436_011535) - 2143670..2144152 (+) 483 WP_003694396.1 CinA family protein -
  ND436_RS11540 (ND436_011540) msrAB 2144236..2145804 (-) 1569 WP_003694393.1 bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB -
  ND436_RS11545 (ND436_011545) pilA 2145950..2147203 (+) 1254 WP_003687004.1 signal recognition particle-docking protein FtsY Machinery gene
  ND436_RS11550 (ND436_011550) - 2147473..2147769 (-) 297 WP_260240075.1 hypothetical protein -
  ND436_RS11555 (ND436_011555) - 2147899..2148030 (+) 132 WP_012503844.1 hypothetical protein -
  ND436_RS11560 (ND436_011560) - 2148004..2148715 (-) 712 Protein_2219 opacity family porin -
  ND436_RS11565 (ND436_011565) pilE 2149261..2149767 (-) 507 WP_265524986.1 pilin Machinery gene
  ND436_RS11570 (ND436_011570) - 2150135..2150278 (-) 144 WP_012503975.1 hypothetical protein -
  ND436_RS11580 (ND436_011580) - 2150581..2150925 (-) 345 Protein_2222 pilin -
  ND436_RS11585 (ND436_011585) - 2150925..2151335 (-) 411 Protein_2223 pilin -

Sequence

Protein


Download         Length: 417 a.a.        Molecular weight: 44389.74 Da        Isoelectric Point: 4.8123

>NTDB_id=736615 ND436_RS11545 WP_003687004.1 2145950..2147203(+) (pilA) [Neisseria gonorrhoeae strain 9071]
MFSFFRRKKKQETPALEEAQVQETAAKVESEVAQIVGNIKEDVESLAESVKGRAESAVETVSGAVEQVKETVAEMPSEAG
EAAERVESAKEAVAETVGEAVGQVQEAVATTEEHKLGWAARLKQGLAKSRDKMAKSLAGVFGGGQIGEDLYEELETVLIT
GDMGMEATEYLMKDVRDRVSLKGLKDGNELRGALKEALYDLIKPLEKPLVLPETKEPFVIMLAGINGAGKTTSIGKLAKY
FQAQGKSVLLAAGDTFRAAAREQLQAWGGRNNVTVISQTTGDSAAVCFDAVQAAKARGIDIVLADTAGRLPTQLHLMEEI
KKVKRVLQKAIPGAPHEIIVVLDANIGQNAVNQVKAFDDALGLTGLIVTKLDGTAKGGILAALASDRPVPVRYIGVGEGI
DDLRPFDARAFVDALLD

Nucleotide


Download         Length: 1254 bp        

>NTDB_id=736615 ND436_RS11545 WP_003687004.1 2145950..2147203(+) (pilA) [Neisseria gonorrhoeae strain 9071]
ATGTTCAGCTTCTTCCGTCGCAAGAAAAAACAGGAAACGCCGGCTCTCGAGGAGGCCCAAGTTCAGGAAACCGCAGCAAA
AGTAGAATCTGAAGTTGCTCAAATAGTTGGAAATATTAAAGAAGATGTCGAATCTTTAGCAGAAAGCGTCAAAGGGCGGG
CCGAATCTGCCGTTGAAACCGTCAGCGGTGCGGTTGAACAGGTAAAGGAAACCGTTGCCGAGATGCCGTCTGAAGCAGGG
GAAGCGGCGGAACGCGTTGAATCCGCAAAAGAAGCTGTTGCCGAAACCGTCGGCGAGGCTGTCGGGCAAGTTCAAGAAGC
CGTTGCGACAACTGAAGAACACAAGCTCGGTTGGGCTGCGCGTTTGAAACAAGGCTTGGCCAAATCACGCGACAAAATGG
CGAAATCGCTGGCCGGCGTGTTCGGCGGCGGACAAATCGGCGAGGATTTGTACGAAGAGCTGGAAACCGTGCTGATTACC
GGCGATATGGGCATGGAGGCCACCGAATACCTGATGAAAGACGTGCGCGACCGCGTCAGCCTCAAAGGGTTGAAAGACGG
CAACGAATTGCGCGGCGCGTTGAAAGAAGCCTTGTACGACCTGATTAAGCCGTTGGAAAAACCGCTGGTCTTGCCCGAAA
CTAAAGAGCCTTTCGTGATTATGCTTGCCGGTATCAACGGCGCGGGCAAAACCACGTCTATCGGCAAACTCGCCAAATAT
TTCCAAGCGCAGGGCAAATCCGTATTGCTGGCGGCAGGCGATACTTTCCGCGCCGCCGCGCGCGAGCAGCTTCAGGCTTG
GGGCGGGCGCAACAATGTAACCGTCATTTCACAAACCACGGGCGATTCCGCCGCCGTGTGCTTCGATGCGGTCCAAGCCG
CGAAAGCGCGCGGGATCGACATCGTGCTTGCCGACACCGCCGGCCGCCTGCCCACGCAGCTTCATTTGATGGAAGAAATC
AAAAAAGTGAAGCGCGTGCTGCAAAAAGCCATTCCCGGCGCGCCGCACGAAATCATCGTCGTACTCGATGCCAATATCGG
GCAAAACGCCGTCAACCAAGTCAAAGCCTTTGACGACGCATTGGGGCTGACGGGGCTTATCGTTACCAAACTCGACGGCA
CGGCAAAAGGCGGCATCCTCGCCGCGCTTGCTTCCGACCGTCCCGTCCCCGTCCGCTACATCGGCGTGGGCGAAGGCATA
GACGACCTGCGCCCGTTTGACGCGCGCGCGTTTGTGGACGCACTGCTGGATTGA

Domains

Predicted by InterproScan.

SRP54-type protein, GTPase domain (SRP54)

(217-416)

SRP54-type protein, helical bundle domain (SRP54_N)

(132-198)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilA Neisseria gonorrhoeae MS11

99.76

100

0.998