Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilL   Type   Machinery gene
Locus tag   NDL70_RS02360 Genome accession   NZ_CP106824
Coordinates   454418..454891 (+) Length   157 a.a.
NCBI ID   WP_229940840.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain 9399     
Function   type IV pilus (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 440079..493705 454418..454891 within 0


Gene organization within MGE regions


Location: 440079..493705
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NDL70_RS02285 (NDL70_02285) - 440079..441062 (+) 984 WP_003687900.1 ribose-phosphate pyrophosphokinase -
  NDL70_RS02290 (NDL70_02290) - 441129..441701 (+) 573 WP_003687901.1 50S ribosomal protein L25/general stress protein Ctc -
  NDL70_RS02295 (NDL70_02295) - 441827..442996 (-) 1170 WP_003687902.1 D-alanyl-D-alanine carboxypeptidase family protein -
  NDL70_RS02300 (NDL70_02300) ilvA 443145..444671 (+) 1527 WP_003687904.1 threonine ammonia-lyase, biosynthetic -
  NDL70_RS02305 (NDL70_02305) - 444727..445803 (-) 1077 WP_003692814.1 sulfate/molybdate ABC transporter ATP-binding protein -
  NDL70_RS02310 (NDL70_02310) cysW 445800..446660 (-) 861 WP_003699617.1 sulfate ABC transporter permease subunit CysW -
  NDL70_RS02315 (NDL70_02315) cysT 446849..447676 (-) 828 WP_003699619.1 sulfate ABC transporter permease subunit CysT -
  NDL70_RS02320 (NDL70_02320) - 447857..448189 (+) 333 WP_003687908.1 hypothetical protein -
  NDL70_RS02325 (NDL70_02325) - 448516..449025 (+) 510 WP_003687909.1 isoprenylcysteine carboxyl methyltransferase family protein -
  NDL70_RS02330 (NDL70_02330) - 449257..449838 (-) 582 WP_003690895.1 superoxide dismutase -
  NDL70_RS02335 (NDL70_02335) dnaB 450002..451408 (+) 1407 WP_003699622.1 replicative DNA helicase -
  NDL70_RS02340 (NDL70_02340) pilH 451562..452227 (+) 666 WP_229940797.1 Tfp pilus assembly protein FimT/FimU Machinery gene
  NDL70_RS02345 (NDL70_02345) pilV 452259..452870 (+) 612 WP_003699626.1 type IV pilus modification protein PilV Machinery gene
  NDL70_RS02350 (NDL70_02350) pilJ 452867..453826 (+) 960 WP_229940798.1 PilW family protein Machinery gene
  NDL70_RS02355 (NDL70_02355) pilK 453805..454416 (+) 612 WP_033911077.1 PilX N-terminal domain-containing pilus assembly protein Machinery gene
  NDL70_RS02360 (NDL70_02360) pilL 454418..454891 (+) 474 WP_229940840.1 PilX family type IV pilin Machinery gene
  NDL70_RS02365 (NDL70_02365) - 454961..455269 (-) 309 WP_025456177.1 AzlD family protein -
  NDL70_RS02370 (NDL70_02370) - 455266..455976 (-) 711 Protein_465 AzlC family ABC transporter permease -
  NDL70_RS02375 (NDL70_02375) dut 456142..456594 (+) 453 WP_003699637.1 dUTP diphosphatase -
  NDL70_RS02380 (NDL70_02380) dapC 456670..457857 (+) 1188 WP_229931672.1 succinyldiaminopimelate transaminase -
  NDL70_RS02385 (NDL70_02385) yaaA 458013..458792 (+) 780 WP_003699641.1 peroxide stress protein YaaA -
  NDL70_RS02400 (NDL70_02400) - 459322..460515 (+) 1194 WP_017146746.1 phage integrase central domain-containing protein -
  NDL70_RS02405 (NDL70_02405) - 460871..461140 (-) 270 WP_003687928.1 hypothetical protein -
  NDL70_RS02410 (NDL70_02410) - 461335..462018 (-) 684 WP_003687929.1 DUF2786 domain-containing protein -
  NDL70_RS11850 - 462299..462565 (-) 267 Protein_472 hypothetical protein -
  NDL70_RS02420 (NDL70_02420) - 462676..462891 (-) 216 WP_003691538.1 hypothetical protein -
  NDL70_RS02425 (NDL70_02425) - 462943..463434 (-) 492 WP_047926688.1 siphovirus Gp157 family protein -
  NDL70_RS02430 (NDL70_02430) - 463431..463613 (-) 183 WP_003691535.1 hypothetical protein -
  NDL70_RS02435 (NDL70_02435) - 463753..464439 (-) 687 WP_010357532.1 phage replication initiation protein, NGO0469 family -
  NDL70_RS02440 (NDL70_02440) - 464508..464669 (-) 162 WP_003691530.1 hypothetical protein -
  NDL70_RS02445 (NDL70_02445) - 464666..464941 (-) 276 WP_151266294.1 NGO1622 family putative holin -
  NDL70_RS02450 (NDL70_02450) - 465095..465427 (-) 333 WP_229940799.1 hypothetical protein -
  NDL70_RS02455 (NDL70_02455) - 465568..465843 (-) 276 WP_050165047.1 hypothetical protein -
  NDL70_RS02460 (NDL70_02460) - 465840..466316 (-) 477 WP_002255718.1 DUF6948 domain-containing protein -
  NDL70_RS02465 (NDL70_02465) - 466349..466549 (-) 201 WP_048654497.1 hypothetical protein -
  NDL70_RS02470 (NDL70_02470) - 466747..467160 (-) 414 WP_003687963.1 hypothetical protein -
  NDL70_RS02475 (NDL70_02475) - 467157..467618 (-) 462 WP_003687965.1 helix-turn-helix domain-containing protein -
  NDL70_RS02480 (NDL70_02480) - 467635..468072 (-) 438 WP_003687967.1 hypothetical protein -
  NDL70_RS02485 (NDL70_02485) - 468185..468901 (-) 717 WP_003687969.1 LexA family transcriptional regulator -
  NDL70_RS02490 (NDL70_02490) - 468976..469206 (+) 231 WP_020997318.1 Cro/CI family transcriptional regulator -
  NDL70_RS02495 (NDL70_02495) - 469286..469441 (+) 156 WP_003698902.1 hypothetical protein -
  NDL70_RS02500 (NDL70_02500) - 469418..469606 (-) 189 WP_003691445.1 hypothetical protein -
  NDL70_RS02505 (NDL70_02505) - 469779..470006 (+) 228 WP_003698261.1 helix-turn-helix domain-containing protein -
  NDL70_RS02510 (NDL70_02510) - 470124..470591 (+) 468 WP_229692802.1 hypothetical protein -
  NDL70_RS02515 (NDL70_02515) - 470686..471189 (+) 504 WP_010360005.1 hypothetical protein -
  NDL70_RS02520 (NDL70_02520) - 471186..472547 (+) 1362 WP_003689132.1 DnaB-like helicase C-terminal domain-containing protein -
  NDL70_RS02525 (NDL70_02525) - 472564..472815 (+) 252 WP_003703849.1 hypothetical protein -
  NDL70_RS02530 (NDL70_02530) - 472829..473323 (+) 495 WP_047923539.1 DUF3310 domain-containing protein -
  NDL70_RS02535 (NDL70_02535) - 473706..473855 (+) 150 WP_047920329.1 phage associated protein -
  NDL70_RS02540 (NDL70_02540) - 473884..474165 (+) 282 WP_003689109.1 hypothetical protein -
  NDL70_RS02545 (NDL70_02545) - 474156..474593 (+) 438 WP_229433529.1 RusA family crossover junction endodeoxyribonuclease -
  NDL70_RS02550 (NDL70_02550) - 474586..474891 (+) 306 WP_025456182.1 DUF1364 domain-containing protein -
  NDL70_RS02555 (NDL70_02555) - 474888..475271 (+) 384 WP_003699764.1 recombination protein NinB -
  NDL70_RS02560 (NDL70_02560) - 475262..475780 (+) 519 WP_003693459.1 HNH endonuclease -
  NDL70_RS02565 (NDL70_02565) - 475845..476267 (+) 423 WP_003690919.1 hypothetical protein -
  NDL70_RS02570 (NDL70_02570) - 476267..476806 (+) 540 WP_003693457.1 hypothetical protein -
  NDL70_RS02575 (NDL70_02575) - 476787..478061 (+) 1275 WP_003698265.1 PBSX family phage terminase large subunit -
  NDL70_RS02580 (NDL70_02580) - 478061..480313 (+) 2253 WP_003699766.1 hypothetical protein -
  NDL70_RS02585 (NDL70_02585) - 480551..481747 (+) 1197 WP_003693452.1 hypothetical protein -
  NDL70_RS02590 (NDL70_02590) - 481744..489051 (+) 7308 WP_229931657.1 PLxRFG domain-containing protein -
  NDL70_RS02595 (NDL70_02595) - 489677..490972 (+) 1296 WP_003693441.1 DUF4043 family protein -
  NDL70_RS02600 (NDL70_02600) - 491030..491503 (+) 474 WP_003693439.1 hypothetical protein -
  NDL70_RS02605 (NDL70_02605) - 491509..491994 (+) 486 WP_003693438.1 hypothetical protein -
  NDL70_RS02610 (NDL70_02610) - 491991..492665 (+) 675 WP_003693436.1 hypothetical protein -
  NDL70_RS02615 (NDL70_02615) - 492668..492817 (+) 150 WP_017146863.1 hypothetical protein -
  NDL70_RS02620 (NDL70_02620) - 492854..493705 (-) 852 WP_003699775.1 Bro-N domain-containing protein -

Sequence

Protein


Download         Length: 157 a.a.        Molecular weight: 17399.22 Da        Isoelectric Point: 9.7225

>NTDB_id=735860 NDL70_RS02360 WP_229940840.1 454418..454891(+) (pilL) [Neisseria gonorrhoeae strain 9399]
MEQKGFTLIEMMIVVAILGIISVIAIPSYQGYIEKGYQSQLYTEMVGINNVLKQFILKNPLDDNQTIKTKLEIFVSGYKM
NPKIAKKYSVSVAFANTEKPRVYRLVGVPKAGTGYTLSVWMNSVGDGYKCRDAASAQAYSETLSANTGCEAFSNRKK

Nucleotide


Download         Length: 474 bp        

>NTDB_id=735860 NDL70_RS02360 WP_229940840.1 454418..454891(+) (pilL) [Neisseria gonorrhoeae strain 9399]
ATGGAACAAAAAGGGTTTACATTGATTGAGATGATGATAGTTGTCGCGATACTCGGCATTATCAGCGTCATTGCCATACC
TTCTTATCAAGGTTATATTGAAAAAGGCTATCAGTCCCAGCTTTATACGGAGATGGTCGGTATCAACAATGTTCTCAAAC
AGTTTATTTTGAAAAATCCCCTGGACGATAATCAGACCATCAAGACCAAACTGGAAATATTTGTCTCAGGCTATAAGATG
AATCCGAAAATTGCCAAAAAATATAGTGTTTCGGTGGCATTTGCCAATACGGAAAAACCAAGGGTATACAGGTTGGTCGG
CGTTCCGAAGGCAGGGACGGGTTATACCTTGTCGGTATGGATGAACAGCGTGGGCGACGGATACAAATGCCGTGATGCCG
CTTCTGCCCAGGCCTATTCGGAGACCTTGTCCGCAAATACCGGCTGTGAAGCTTTCTCTAATCGTAAAAAATAG

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(3-25)

Minor type IV pilin, PilX (Pilin_PilX)

(32-157)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilL Neisseria gonorrhoeae MS11

90.446

100

0.904
  pilX Neisseria meningitidis 8013

87.898

100

0.879