Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYE   Type   Machinery gene
Locus tag   FNL60_RS01245 Genome accession   NZ_AP019720
Coordinates   239969..240262 (+) Length   97 a.a.
NCBI ID   WP_002263439.1    Uniprot ID   -
Organism   Streptococcus mutans strain NBRC 13955     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 234969..245262
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FNL60_RS01220 (SM3g_02080) - 236871..237254 (+) 384 WP_002264248.1 DUF1033 family protein -
  FNL60_RS01225 (SM3g_02090) comYA 237384..238325 (+) 942 WP_002264247.1 competence type IV pilus ATPase ComGA Machinery gene
  FNL60_RS01230 (SM3g_02100) comYB 238261..239292 (+) 1032 WP_255262721.1 competence type IV pilus assembly protein ComGB Machinery gene
  FNL60_RS01235 (SM3g_02110) comYC 239292..239606 (+) 315 WP_002263437.1 competence type IV pilus major pilin ComGC Machinery gene
  FNL60_RS01240 (SM3g_02120) comYD 239593..239997 (+) 405 WP_002264246.1 competence type IV pilus minor pilin ComGD Machinery gene
  FNL60_RS01245 (SM3g_02130) comYE 239969..240262 (+) 294 WP_002263439.1 competence type IV pilus minor pilin ComGE Machinery gene
  FNL60_RS01250 (SM3g_02140) comYF 240249..240683 (+) 435 WP_002264245.1 competence type IV pilus minor pilin ComGF Machinery gene
  FNL60_RS01255 (SM3g_02150) comYG 240661..241050 (+) 390 WP_002263441.1 competence type IV pilus minor pilin ComGG Machinery gene
  FNL60_RS01260 (SM3g_02160) comYH 241105..242058 (+) 954 WP_002264244.1 class I SAM-dependent methyltransferase Machinery gene
  FNL60_RS01265 (SM3g_02170) - 242117..243316 (+) 1200 WP_002263443.1 acetate kinase -
  FNL60_RS01270 (SM3g_02180) - 243869..244114 (+) 246 WP_002263444.1 helix-turn-helix transcriptional regulator -
  FNL60_RS01275 (SM3g_02190) - 244083..244523 (+) 441 WP_002263445.1 hypothetical protein -
  FNL60_RS01280 (SM3g_02200) - 244576..245238 (+) 663 WP_002266816.1 CPBP family intramembrane glutamic endopeptidase -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 11001.91 Da        Isoelectric Point: 9.4908

>NTDB_id=73501 FNL60_RS01245 WP_002263439.1 239969..240262(+) (comYE) [Streptococcus mutans strain NBRC 13955]
MVSIKKQKVKAYILLESLVALGLFVTITTLILTQLSHYQERTAKNLQKQEILNLAIMALQTQQDHLSFNGVSVTVVKNQG
ETIVYHDHEEVINLVKK

Nucleotide


Download         Length: 294 bp        

>NTDB_id=73501 FNL60_RS01245 WP_002263439.1 239969..240262(+) (comYE) [Streptococcus mutans strain NBRC 13955]
GTGGTCAGTATAAAAAAACAGAAAGTTAAAGCTTATATTCTTCTAGAAAGTTTAGTTGCTTTGGGACTTTTCGTAACCAT
CACAACTTTAATTCTTACTCAGTTGAGTCATTATCAGGAAAGAACAGCTAAAAATTTACAAAAACAAGAAATATTGAATT
TAGCAATAATGGCTCTTCAAACTCAGCAAGATCATTTAAGCTTCAACGGCGTCAGTGTTACGGTTGTTAAAAATCAAGGG
GAAACTATAGTTTATCATGATCATGAGGAGGTTATCAATCTTGTTAAAAAGTAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYE Streptococcus mutans UA140

100

100

1
  comYE Streptococcus mutans UA159

100

100

1
  comGE/cglE Streptococcus pneumoniae Rx1

44.444

92.784

0.412
  comGE/cglE Streptococcus pneumoniae D39

44.444

92.784

0.412
  comGE/cglE Streptococcus pneumoniae R6

44.444

92.784

0.412
  comGE/cglE Streptococcus pneumoniae TIGR4

44.444

92.784

0.412
  comGE/cglE Streptococcus mitis NCTC 12261

44.444

92.784

0.412
  comGE/cglE Streptococcus mitis SK321

44.444

92.784

0.412

Multiple sequence alignment