Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   P5647_RS18220 Genome accession   NZ_CP120622
Coordinates   3507668..3509653 (-) Length   661 a.a.
NCBI ID   WP_003243787.1    Uniprot ID   P37954
Organism   Bacillus subtilis strain DSM 1090     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 3502668..3514653
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P5647_RS18200 (P5647_18200) yvlA 3503170..3503496 (-) 327 WP_003244375.1 protein YvlA -
  P5647_RS18205 (P5647_18205) - 3503714..3503944 (+) 231 WP_003228059.1 hypothetical protein -
  P5647_RS18210 (P5647_18210) - 3504143..3504706 (-) 564 Protein_3533 flagellin -
  P5647_RS18215 (P5647_18215) uvrA 3504787..3507660 (-) 2874 WP_003228057.1 excinuclease ABC subunit UvrA Machinery gene
  P5647_RS18220 (P5647_18220) uvrB 3507668..3509653 (-) 1986 WP_003243787.1 excinuclease ABC subunit UvrB Machinery gene
  P5647_RS18225 (P5647_18225) csbA 3509839..3510069 (-) 231 WP_003228053.1 CsbA family protein -
  P5647_RS18230 (P5647_18230) fpsC 3510516..3513011 (+) 2496 WP_003243243.1 PEP/pyruvate-binding domain-containing protein -
  P5647_RS18235 (P5647_18235) yvkB 3513087..3513656 (+) 570 WP_003244088.1 TetR/AcrR family transcriptional regulator -

Sequence

Protein


Download         Length: 661 a.a.        Molecular weight: 76327.13 Da        Isoelectric Point: 5.2528

>NTDB_id=733490 P5647_RS18220 WP_003243787.1 3507668..3509653(-) (uvrB) [Bacillus subtilis strain DSM 1090]
MKDRFELVSKYQPQGDQPKAIEKLVKGIQEGKKHQTLLGATGTGKTFTVSNLIKEVNKPTLVIAHNKTLAGQLYSEFKEF
FPNNAVEYFVSYYDYYQPEAYVPQTDTFIEKDASINDEIDKLRHSATSALFERRDVIIIASVSCIYGLGSPEEYREMVVS
LRTEMEIERNELLRKLVDIQYARNDIDFQRGTFRVRGDVVEIFPASRDEHCVRVEFFGDEIERIREVDALTGEILGDRDH
VAIFPASHFVTRAEKMEKAIQNIEKELEEQLKVMHENGKLLEAQRLEQRTRYDLEMMREMGFCSGIENYSRHLTLRPPGS
TPYTLLDYFPDDFMIVVDESHVTIPQVRGMFNGDQARKQVLVDHGFRLPSALDNRPLRFEEFEKHMHNIVYVSATPGPYE
IEHTDEMVEQIIRPTGLLDPLIDVRPIEGQIDDLIGEIQARIERNERVLVTTLTKKMSEDLTDYLKEIGIKVNYLHSEIK
TLERIEIIRDLRLGKYDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNAEGRVIMYADKITKSM
EIAINETKRRREQQERFNEEHGITPKTINKEIRDVIRATVAAEDKAEYKTKAAPKLSKMTKKERQKVVEQMEHEMKEAAK
ALDFERAAELRDLLLELKAEG

Nucleotide


Download         Length: 1986 bp        

>NTDB_id=733490 P5647_RS18220 WP_003243787.1 3507668..3509653(-) (uvrB) [Bacillus subtilis strain DSM 1090]
GTGAAAGATCGCTTTGAGTTAGTCTCGAAATATCAGCCCCAGGGAGATCAGCCGAAAGCCATTGAAAAGCTTGTGAAAGG
AATTCAGGAGGGCAAGAAGCATCAGACTCTGCTGGGTGCAACAGGAACTGGGAAAACATTTACGGTGTCCAATTTGATTA
AAGAAGTCAATAAGCCGACTCTCGTGATTGCCCATAACAAAACCCTTGCTGGACAGCTTTACAGTGAGTTCAAGGAATTT
TTTCCGAACAATGCTGTCGAGTATTTTGTCAGCTACTATGATTATTATCAGCCGGAGGCGTATGTGCCTCAAACGGATAC
ATTTATAGAGAAAGACGCTAGTATTAATGATGAAATTGATAAACTGAGACACTCCGCCACATCAGCTTTGTTTGAGCGCA
GAGATGTCATTATTATTGCGAGTGTGTCTTGTATATACGGCCTCGGTTCGCCTGAGGAATACCGGGAAATGGTCGTGTCA
CTGCGGACTGAAATGGAAATTGAGCGCAACGAGCTGCTCAGAAAACTTGTAGACATCCAATATGCCCGCAACGATATCGA
CTTTCAGCGCGGTACATTTCGTGTGCGCGGGGATGTAGTGGAAATCTTTCCGGCATCCCGTGATGAGCATTGTGTCAGAG
TTGAATTTTTCGGTGACGAAATCGAACGGATTCGGGAAGTAGATGCGCTGACAGGAGAAATTCTCGGCGACCGAGATCAT
GTTGCGATTTTCCCGGCATCCCACTTCGTAACGCGGGCCGAGAAAATGGAGAAGGCGATTCAAAATATCGAGAAGGAGCT
TGAGGAGCAGCTGAAGGTCATGCATGAAAACGGAAAGCTCCTTGAAGCGCAGCGTTTAGAGCAGCGGACAAGATATGATC
TTGAAATGATGCGTGAAATGGGTTTCTGCTCCGGCATCGAGAACTATTCAAGACATTTGACTCTGCGGCCTCCAGGTTCA
ACGCCGTATACGCTTCTTGATTATTTCCCAGACGATTTTATGATCGTGGTGGATGAGTCGCATGTGACAATTCCTCAGGT
GCGCGGCATGTTTAACGGAGACCAGGCGCGGAAACAGGTGCTCGTGGATCACGGCTTCCGGCTTCCATCAGCGCTTGATA
ACCGTCCGCTTCGTTTTGAGGAATTTGAAAAGCATATGCACAATATCGTGTATGTATCAGCAACACCAGGGCCGTACGAG
ATTGAACATACAGATGAAATGGTCGAACAGATCATTCGTCCGACGGGGCTTCTTGACCCGCTTATTGACGTCCGTCCAAT
CGAAGGTCAGATTGACGACTTGATCGGCGAAATTCAAGCAAGAATCGAGCGGAATGAACGGGTGCTTGTGACAACTTTGA
CGAAGAAGATGTCAGAGGATCTGACCGATTATTTAAAGGAAATCGGCATTAAAGTAAACTATCTGCATTCTGAGATCAAG
ACGCTTGAACGGATTGAAATTATCCGCGACCTGCGCCTTGGCAAGTACGATGTGCTTGTCGGCATCAACCTGCTGAGGGA
AGGTTTGGACATTCCCGAAGTATCCCTTGTTGCGATTTTGGATGCGGATAAGGAAGGTTTCCTTCGTTCGGAGCGGTCGC
TGATCCAGACCATCGGACGGGCAGCGAGAAATGCGGAAGGCCGCGTCATTATGTACGCCGATAAAATAACGAAGTCTATG
GAAATTGCGATTAATGAAACAAAACGCCGCCGCGAGCAGCAGGAGCGGTTTAACGAAGAGCACGGCATTACGCCGAAAAC
GATAAATAAAGAAATTCGCGATGTCATTCGTGCCACAGTAGCAGCTGAGGATAAAGCGGAATACAAAACAAAAGCCGCGC
CGAAGCTGTCGAAAATGACGAAGAAAGAACGCCAGAAAGTCGTTGAACAGATGGAGCATGAAATGAAGGAAGCCGCCAAG
GCGCTTGACTTTGAGAGAGCCGCGGAGCTTCGCGATTTACTTTTAGAGCTAAAAGCGGAAGGATGA

Domains

Predicted by InterProScan.

Type III restriction enzyme, res subunit (ResIII)

(12-138)

UvrB interaction domain (UvrB_inter)

(159-249)

UvrB/uvrC motif (UVR)

(626-659)

Helicase conserved C-terminal domain (Helicase_C)

(440-544)

Ultra-violet resistance protein B (UvrB)

(551-593)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  PDB 2D7D
  PDB 2NMV
  PDB 3V4R

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae TIGR4

70.561

99.697

0.703
  uvrB Streptococcus pneumoniae R6

70.41

99.697

0.702
  uvrB Streptococcus pneumoniae D39

70.41

99.697

0.702