Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   N5913_RS15635 Genome accession   NZ_CP104649
Coordinates   2976537..2977661 (-) Length   374 a.a.
NCBI ID   WP_000228545.1    Uniprot ID   A0AAV3H2U0
Organism   Escherichia coli strain PNUSAE008512     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 2971537..2982661
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N5913_RS15605 (N5913_15605) yrdA 2973337..2973891 (+) 555 WP_001286216.1 gamma carbonic anhydrase family protein -
  N5913_RS15610 (N5913_15610) yrdB 2973867..2974124 (-) 258 WP_001070590.1 DUF1488 domain-containing protein -
  N5913_RS15615 (N5913_15615) aroE 2974121..2974939 (-) 819 WP_000451254.1 shikimate dehydrogenase -
  N5913_RS15620 (N5913_15620) tsaC 2974944..2975516 (-) 573 WP_001301437.1 L-threonylcarbamoyladenylate synthase type 1 TsaC -
  N5913_RS15625 (N5913_15625) yrdD 2975521..2976063 (-) 543 WP_001129722.1 type I DNA topoisomerase -
  N5913_RS15630 (N5913_15630) smg 2976092..2976565 (-) 474 WP_000460672.1 DUF494 family protein Smg -
  N5913_RS15635 (N5913_15635) dprA 2976537..2977661 (-) 1125 WP_000228545.1 DNA-protecting protein DprA Machinery gene
  N5913_RS15640 (N5913_15640) def 2977791..2978300 (+) 510 WP_000114984.1 peptide deformylase -
  N5913_RS15645 (N5913_15645) fmt 2978315..2979262 (+) 948 WP_000004459.1 methionyl-tRNA formyltransferase -
  N5913_RS15650 (N5913_15650) rsmB 2979308..2980597 (+) 1290 WP_001301795.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  N5913_RS15655 (N5913_15655) trkA 2980619..2981995 (+) 1377 WP_000691382.1 Trk system potassium transporter TrkA -
  N5913_RS15660 (N5913_15660) mscL 2982125..2982535 (+) 411 WP_000022442.1 large-conductance mechanosensitive channel protein MscL -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 41034.02 Da        Isoelectric Point: 6.3845

>NTDB_id=731213 N5913_RS15635 WP_000228545.1 2976537..2977661(-) (dprA) [Escherichia coli strain PNUSAE008512]
MVDTEIWLRLMSISSLYGDDMVRIAHWLARQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLAKHGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHARLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE
VTPVDVVAERAGRPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=731213 N5913_RS15635 WP_000228545.1 2976537..2977661(-) (dprA) [Escherichia coli strain PNUSAE008512]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGTATCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG
GCTGGCAAGACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGGAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGTGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGAAGCATGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTAGCGCATAAAGCAGCCTTACAGGTAAAT
GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGTCATGCCCGACTGGCTGCCAGTCTGCT
TGAACAGGGGGGCGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGTAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGAGAAGTTTTTGCCTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCGACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Domains

Predicted by InterproScan.

DprA winged helix domain (DprA_WH)

(312-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

48.78

98.663

0.481
  dprA Glaesserella parasuis strain SC1401

45.401

90.107

0.409
  dprA Vibrio cholerae strain A1552

49.355

82.888

0.409
  dprA Haemophilus influenzae Rd KW20

44.214

90.107

0.398
  dprA Legionella pneumophila strain ERS1305867

44.545

88.235

0.393