Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   N4502_RS11885 Genome accession   NZ_CP104371
Coordinates   2444269..2445393 (-) Length   374 a.a.
NCBI ID   WP_000228516.1    Uniprot ID   -
Organism   Escherichia coli strain 2021CK-01784     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 2439269..2450393
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N4502_RS11855 (N4502_11855) yrdA 2441069..2441623 (+) 555 WP_001286216.1 gamma carbonic anhydrase family protein -
  N4502_RS11860 (N4502_11860) yrdB 2441599..2441856 (-) 258 WP_001070567.1 DUF1488 domain-containing protein -
  N4502_RS11865 (N4502_11865) aroE 2441853..2442671 (-) 819 WP_001590789.1 shikimate dehydrogenase -
  N4502_RS11870 (N4502_11870) tsaC 2442676..2443248 (-) 573 WP_001297709.1 L-threonylcarbamoyladenylate synthase type 1 TsaC -
  N4502_RS11875 (N4502_11875) yrdD 2443253..2443795 (-) 543 WP_001129723.1 type I DNA topoisomerase -
  N4502_RS11880 (N4502_11880) smg 2443824..2444297 (-) 474 WP_000460672.1 DUF494 family protein Smg -
  N4502_RS11885 (N4502_11885) dprA 2444269..2445393 (-) 1125 WP_000228516.1 DNA-protecting protein DprA Machinery gene
  N4502_RS11890 (N4502_11890) def 2445523..2446032 (+) 510 WP_000114984.1 peptide deformylase -
  N4502_RS11895 (N4502_11895) fmt 2446047..2446994 (+) 948 WP_000004464.1 methionyl-tRNA formyltransferase -
  N4502_RS11900 (N4502_11900) rsmB 2447040..2448329 (+) 1290 WP_001551736.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  N4502_RS11905 (N4502_11905) trkA 2448351..2449727 (+) 1377 WP_000691382.1 Trk system potassium transporter TrkA -
  N4502_RS11910 (N4502_11910) mscL 2449857..2450267 (+) 411 WP_000022442.1 large-conductance mechanosensitive channel protein MscL -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40888.88 Da        Isoelectric Point: 6.5011

>NTDB_id=729181 N4502_RS11885 WP_000228516.1 2444269..2445393(-) (dprA) [Escherichia coli strain 2021CK-01784]
MVDTEIWLRLMSISSLYGDDMVRIAHLLAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLSWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVAGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLAKRGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHARLATSLLEHGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPLGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=729181 N4502_RS11885 WP_000228516.1 2444269..2445393(-) (dprA) [Escherichia coli strain 2021CK-01784]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGCATCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTT
GCTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACTGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTCTTGGTTGGAGCAACCCAACCATCATTTAATTCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTTGCGACGACAGATTACCCCGGCGCACTGTTTGTTGCAGGAGAACTGCACGCGCTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGAAGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT
GGCGTCAGCATTGCTGTATTAGGGAATGGACTTAATACCATTCATCCGCGTCGCCATGCCCGACTGGCTACCAGTTTGCT
TGAACATGGTGGGGCTCTTGTCTCGGAATTTCCCCTCGATGTTCCTCCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGTGAAGTTTTTGCCTTGCCGGGTCCATTAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTAACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)

DprA winged helix domain (DprA_WH)

(312-357)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

48.78

98.663

0.481
  dprA Vibrio cholerae strain A1552

44.324

98.93

0.438
  dprA Glaesserella parasuis strain SC1401

44.068

94.652

0.417
  dprA Haemophilus influenzae Rd KW20

43.917

90.107

0.396
  dprA Legionella pneumophila strain ERS1305867

43.363

90.642

0.393