Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   N2A96_RS02220 Genome accession   NZ_CP104047
Coordinates   404567..405253 (+) Length   228 a.a.
NCBI ID   WP_003104116.1    Uniprot ID   A0A0E2UE77
Organism   Streptococcus parauberis strain KSP10     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 399567..410253
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N2A96_RS02195 (N2A96_02195) - 399849..401225 (-) 1377 WP_003106203.1 TrkH family potassium uptake protein -
  N2A96_RS02200 (N2A96_02200) rsmG 401310..402023 (-) 714 WP_003104507.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  N2A96_RS02205 (N2A96_02205) - 402167..402724 (+) 558 WP_003103300.1 LemA family protein -
  N2A96_RS02210 (N2A96_02210) htpX 402756..403652 (+) 897 WP_003106209.1 zinc metalloprotease HtpX -
  N2A96_RS02215 (N2A96_02215) - 403778..404311 (+) 534 WP_260003371.1 DUF177 domain-containing protein -
  N2A96_RS02220 (N2A96_02220) covR 404567..405253 (+) 687 WP_003104116.1 two-component system response regulator CovR Regulator
  N2A96_RS02225 (N2A96_02225) - 405255..406763 (+) 1509 WP_003106210.1 ATP-binding protein -
  N2A96_RS02230 (N2A96_02230) nrdR 406902..407396 (+) 495 WP_003105627.1 transcriptional regulator NrdR -
  N2A96_RS02235 (N2A96_02235) - 407380..408564 (+) 1185 WP_003106211.1 DnaD domain protein -
  N2A96_RS02240 (N2A96_02240) dnaI 408565..409467 (+) 903 WP_003103419.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26596.58 Da        Isoelectric Point: 4.6586

>NTDB_id=727292 N2A96_RS02220 WP_003104116.1 404567..405253(+) (covR) [Streptococcus parauberis strain KSP10]
MTKKILIVEDEKNLARFVSLELQHEGYEVSVEVNGREGLETALEKDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMT
ARDSIMDVVAGLDRGADDYIVKPFAIEELLARIRAIFRRQDIETEKKAPNQGVYRDLVLNPQNRSVNRGDEEISLTKREY
DLLNILMTNMNRVMTREELLSSVWKYDEAVETNVVDVYIRYLRGKIDMPGRESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 687 bp        

>NTDB_id=727292 N2A96_RS02220 WP_003104116.1 404567..405253(+) (covR) [Streptococcus parauberis strain KSP10]
ATGACTAAGAAAATTTTAATTGTTGAAGACGAAAAGAATCTAGCAAGATTTGTTTCTCTTGAATTACAACATGAAGGCTA
TGAAGTTAGTGTTGAAGTAAACGGTAGAGAAGGACTTGAAACTGCATTAGAAAAAGATTTTGATTTAATTCTGCTTGACT
TAATGCTTCCTGAGATGGATGGTTTTGAAGTTACTCGCCGCTTACAAACAGAAAAAACAACTTATATCATGATGATGACT
GCGCGTGATTCAATCATGGATGTTGTTGCAGGTCTTGACCGTGGTGCGGATGACTATATCGTAAAACCTTTTGCGATTGA
AGAATTGTTGGCACGTATTCGTGCAATCTTCCGTCGACAAGATATCGAAACTGAGAAGAAAGCGCCAAATCAAGGCGTTT
ACCGCGATTTAGTGTTAAATCCTCAAAATCGTTCAGTTAATCGTGGAGATGAAGAAATTTCATTAACAAAACGTGAATAT
GATTTATTAAATATTTTGATGACTAATATGAACCGTGTTATGACTCGTGAAGAGTTATTATCAAGTGTATGGAAGTATGA
TGAAGCTGTTGAAACAAACGTAGTTGATGTTTATATTCGTTATCTTCGTGGCAAAATTGATATGCCAGGAAGAGAATCTT
ACATCCAAACAGTTCGTGGAATGGGATATGTAATTCGCGAGAAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-224)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E2UE77

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

83.406

100

0.838
  covR Lactococcus lactis subsp. lactis strain DGCC12653

66.96

99.561

0.667
  vicR Streptococcus mutans UA159

43.723

100

0.443
  micA Streptococcus pneumoniae Cp1015

43.478

100

0.439