Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   N2A93_RS02225 Genome accession   NZ_CP104046
Coordinates   404565..405251 (+) Length   228 a.a.
NCBI ID   WP_003104116.1    Uniprot ID   A0A0E2UE77
Organism   Streptococcus parauberis strain KSP14     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 399565..410251
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N2A93_RS02200 (N2A93_02200) - 399847..401223 (-) 1377 WP_003106203.1 TrkH family potassium uptake protein -
  N2A93_RS02205 (N2A93_02205) rsmG 401308..402021 (-) 714 WP_003104507.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  N2A93_RS02210 (N2A93_02210) - 402165..402722 (+) 558 WP_003103300.1 LemA family protein -
  N2A93_RS02215 (N2A93_02215) htpX 402754..403650 (+) 897 WP_003106209.1 zinc metalloprotease HtpX -
  N2A93_RS02220 (N2A93_02220) - 403776..404309 (+) 534 WP_003102943.1 DUF177 domain-containing protein -
  N2A93_RS02225 (N2A93_02225) covR 404565..405251 (+) 687 WP_003104116.1 two-component system response regulator CovR Regulator
  N2A93_RS02230 (N2A93_02230) - 405253..406761 (+) 1509 WP_003106210.1 ATP-binding protein -
  N2A93_RS02235 (N2A93_02235) nrdR 406900..407394 (+) 495 WP_003105627.1 transcriptional regulator NrdR -
  N2A93_RS02240 (N2A93_02240) - 407378..408562 (+) 1185 WP_003106211.1 DnaD domain protein -
  N2A93_RS02245 (N2A93_02245) dnaI 408563..409465 (+) 903 WP_003103419.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26596.58 Da        Isoelectric Point: 4.6586

>NTDB_id=727240 N2A93_RS02225 WP_003104116.1 404565..405251(+) (covR) [Streptococcus parauberis strain KSP14]
MTKKILIVEDEKNLARFVSLELQHEGYEVSVEVNGREGLETALEKDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMT
ARDSIMDVVAGLDRGADDYIVKPFAIEELLARIRAIFRRQDIETEKKAPNQGVYRDLVLNPQNRSVNRGDEEISLTKREY
DLLNILMTNMNRVMTREELLSSVWKYDEAVETNVVDVYIRYLRGKIDMPGRESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 687 bp        

>NTDB_id=727240 N2A93_RS02225 WP_003104116.1 404565..405251(+) (covR) [Streptococcus parauberis strain KSP14]
ATGACTAAGAAAATTTTAATTGTTGAAGACGAAAAGAATCTAGCAAGATTTGTTTCTCTTGAATTACAACATGAAGGCTA
TGAAGTTAGTGTTGAAGTAAACGGTAGAGAAGGACTTGAAACTGCATTAGAAAAAGATTTTGATTTAATTCTGCTTGACT
TAATGCTTCCTGAGATGGATGGTTTTGAAGTTACTCGCCGCTTACAAACAGAAAAAACAACTTATATCATGATGATGACT
GCGCGTGATTCAATCATGGATGTTGTTGCAGGTCTTGACCGTGGTGCGGATGACTATATCGTAAAACCTTTTGCGATTGA
AGAATTGTTGGCACGTATTCGTGCAATCTTCCGTCGACAAGATATCGAAACTGAGAAGAAAGCGCCAAATCAAGGCGTTT
ACCGCGATTTAGTGTTAAATCCTCAAAATCGTTCAGTTAATCGTGGAGATGAAGAAATTTCATTAACAAAACGTGAATAT
GATTTATTAAATATTTTGATGACTAATATGAACCGTGTTATGACTCGTGAAGAGTTATTATCAAGTGTATGGAAGTATGA
TGAAGCTGTTGAAACAAACGTAGTTGATGTTTATATTCGTTATCTTCGTGGCAAAATTGATATGCCAGGAAGAGAATCTT
ACATCCAAACAGTTCGTGGAATGGGATATGTAATTCGCGAGAAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-224)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E2UE77

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

83.406

100

0.838
  covR Lactococcus lactis subsp. lactis strain DGCC12653

66.96

99.561

0.667
  vicR Streptococcus mutans UA159

43.723

100

0.443
  micA Streptococcus pneumoniae Cp1015

43.478

100

0.439