Detailed information NTG0726117

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: NX081_RS18375
• Genome accession: NZ_CP103856
• Coordinates: 3653031..3654194 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain SRCM116265
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3648031..3659194

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NX081_RS18345 (NX081_18345)	-	3648296..3648715 (-)	420	WP_025285352.1	TIGR03826 family flagellar region protein	-
NX081_RS18350 (NX081_18350)	comFC	3648789..3649478 (-)	690	WP_197714552.1	phosphoribosyltransferase family protein	Machinery gene
NX081_RS18355 (NX081_18355)	-	3649484..3649768 (-)	285	WP_003151389.1	late competence development ComFB family protein	-
NX081_RS18360 (NX081_18360)	comFA	3649826..3651211 (-)	1386	WP_060562494.1	DEAD/DEAH box helicase	Machinery gene
NX081_RS18365 (NX081_18365)	-	3651319..3652167 (-)	849	WP_003151387.1	DegV family protein	-
NX081_RS18370 (NX081_18370)	degU	3652265..3652954 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
NX081_RS18375 (NX081_18375)	degS	3653031..3654194 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
NX081_RS18380 (NX081_18380)	-	3654417..3655064 (+)	648	WP_007614107.1	YigZ family protein	-
NX081_RS18385 (NX081_18385)	-	3655069..3656289 (+)	1221	WP_012118574.1	LCP family protein	-
NX081_RS18390 (NX081_18390)	-	3656388..3657464 (-)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
NX081_RS18395 (NX081_18395)	-	3657597..3658793 (-)	1197	WP_060562493.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=726117 NX081_RS18375 WP_007407484.1 3653031..3654194(-) (degS) [Bacillus velezensis strain SRCM116265]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=726117 NX081_RS18375 WP_007407484.1 3653031..3654194(-) (degS) [Bacillus velezensis strain SRCM116265]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTAGGTCTTCAGGAAATCATTGAAC
GGTCAGAATCGTTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCTGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951