Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   NYR63_RS01060 Genome accession   NZ_CP103834
Coordinates   213864..215159 (+) Length   431 a.a.
NCBI ID   WP_279457767.1    Uniprot ID   -
Organism   Actinobacillus genomosp. 1 strain 3216     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 208864..220159
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NYR63_RS01035 (NYR63_01030) - 209037..211604 (-) 2568 WP_279457762.1 penicillin-binding protein 1A -
  NYR63_RS01040 (NYR63_01035) - 211743..212423 (+) 681 WP_279457764.1 pilus assembly protein PilM -
  NYR63_RS01045 (NYR63_01040) - 212405..212926 (+) 522 WP_279457765.1 hypothetical protein -
  NYR63_RS01050 (NYR63_01045) - 213026..213457 (+) 432 WP_279458517.1 chromosome segregation protein -
  NYR63_RS01055 (NYR63_01050) - 213450..213854 (+) 405 WP_279457766.1 hypothetical protein -
  NYR63_RS01060 (NYR63_01055) comE 213864..215159 (+) 1296 WP_279457767.1 type IV pilus secretin PilQ Machinery gene
  NYR63_RS01065 (NYR63_01060) nusB 215285..215698 (+) 414 WP_279457768.1 transcription antitermination factor NusB -
  NYR63_RS01070 (NYR63_01065) thiL 215762..216730 (+) 969 WP_279457769.1 thiamine-phosphate kinase -
  NYR63_RS01075 (NYR63_01070) - 216740..217213 (+) 474 WP_279457770.1 phosphatidylglycerophosphatase A -
  NYR63_RS01080 (NYR63_01075) - 217226..217849 (+) 624 WP_279458518.1 LysE family transporter -
  NYR63_RS01085 (NYR63_01080) - 217910..219007 (-) 1098 WP_279457771.1 TrmH family RNA methyltransferase -
  NYR63_RS01090 (NYR63_01085) suhB 219174..219986 (+) 813 WP_279457772.1 inositol-1-monophosphatase -

Sequence

Protein


Download         Length: 431 a.a.        Molecular weight: 47778.74 Da        Isoelectric Point: 7.6943

>NTDB_id=725812 NYR63_RS01060 WP_279457767.1 213864..215159(+) (comE) [Actinobacillus genomosp. 1 strain 3216]
MNRMILLLFFMLSSVIAHAFSISLKNAPTAEILSYLAEEYGKNIVLSDNIETNTTLRIENSDFDSVLKSITQANKLTSAY
ENQIYFISHKKDERTTSVGLNAELLKPKLITKTIKLDYAKAAEVIESLTKGSGHFLSENGYLHFDDRSNSLIIKDSPESM
KNIVKLIRNLDKPTEQIAIEARIVTISSENLQELGVRWGIFSPANGHHKIAGSLEANGLPNTNRLNVNFPVNNAASIALQ
VAKINGRVLDLELTALEQENDVEIIASPRLLTTNKKPASIKQGTEIPYVLYNRKDEVKNIEFKEAVLGLQVTPHISNDNQ
ILLDLIVTQNSPNSAASTINGLVTIDKQELNTQVFAQHGETIVLGGIFQHLAAKGEDRVPILGSIPVLKKLFSHSSDRIS
KRELVIFVTPYIVKNEKQQISSHSSQKLPPK

Nucleotide


Download         Length: 1296 bp        

>NTDB_id=725812 NYR63_RS01060 WP_279457767.1 213864..215159(+) (comE) [Actinobacillus genomosp. 1 strain 3216]
ATGAACAGAATGATTTTGCTACTCTTTTTTATGTTGTCCTCTGTGATTGCACATGCTTTTTCTATTTCATTAAAAAATGC
GCCGACAGCAGAAATTTTAAGCTACTTAGCCGAAGAGTACGGCAAAAATATTGTGTTAAGCGACAATATTGAAACAAATA
CCACCTTAAGGATTGAAAATAGCGATTTTGATAGTGTGCTAAAAAGTATTACTCAAGCAAATAAGCTGACCAGTGCCTAT
GAAAATCAGATCTATTTTATTAGCCATAAAAAAGATGAAAGAACTACTAGCGTAGGCTTAAATGCTGAATTGTTAAAACC
TAAGTTAATTACTAAAACCATCAAGTTAGATTATGCCAAAGCGGCGGAAGTAATTGAATCTTTAACCAAAGGTAGCGGTC
ATTTTTTATCGGAAAACGGTTATTTGCATTTTGATGATCGTAGTAATAGTTTGATCATTAAAGATAGTCCGGAATCAATG
AAAAATATCGTGAAATTAATTAGAAATTTGGATAAGCCGACCGAGCAAATTGCGATTGAAGCGAGAATTGTCACGATAAG
TAGTGAGAATTTACAAGAGTTAGGCGTACGCTGGGGGATATTTTCTCCGGCAAACGGACATCATAAAATTGCCGGTTCGC
TTGAAGCGAATGGCCTACCGAATACTAACCGTTTAAACGTAAATTTTCCGGTAAATAATGCTGCTTCTATTGCGTTACAA
GTGGCTAAAATTAATGGTCGTGTGCTTGATTTGGAATTAACCGCTTTAGAGCAGGAAAATGATGTGGAAATTATTGCCAG
TCCTCGTTTGCTGACCACCAATAAGAAGCCGGCAAGTATTAAGCAAGGGACGGAAATTCCTTATGTGTTATATAACCGTA
AAGATGAAGTGAAAAATATTGAATTTAAAGAAGCGGTTTTAGGCTTGCAAGTGACACCGCATATTTCAAACGATAATCAG
ATTTTGCTCGATCTGATAGTGACGCAAAATTCACCGAATTCAGCCGCTTCAACAATTAATGGTTTAGTGACGATTGATAA
ACAAGAACTCAATACGCAAGTATTTGCTCAGCATGGTGAAACCATTGTACTTGGTGGTATTTTTCAACATTTAGCCGCAA
AAGGAGAGGACAGAGTCCCTATTTTAGGTTCAATTCCGGTACTTAAAAAATTATTTAGCCATTCCAGTGATAGGATCAGT
AAGCGCGAATTAGTTATTTTCGTTACGCCTTATATCGTCAAAAACGAAAAACAGCAAATTTCCTCGCATTCTTCACAGAA
ATTACCGCCAAAATAG

Domains

Predicted by InterproScan.

Bacterial type II/III secretion system short domain (Secretin_N)

(111-176)

Bacterial type II and III secretion system protein (Secretin)

(255-414)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Glaesserella parasuis strain SC1401

66.986

96.984

0.65
  comE Haemophilus influenzae Rd KW20

56.14

92.575

0.52
  comE Haemophilus influenzae 86-028NP

55.611

93.039

0.517
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

43.237

96.056

0.415
  pilQ Vibrio cholerae strain A1552

43.237

96.056

0.415
  pilQ Vibrio campbellii strain DS40M4

41.608

98.144

0.408