Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   NYR89_RS01365 Genome accession   NZ_CP103833
Coordinates   264856..266151 (+) Length   431 a.a.
NCBI ID   WP_279446021.1    Uniprot ID   -
Organism   Actinobacillus arthritidis strain CCUG24862     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 259856..271151
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NYR89_RS01340 (NYR89_01335) - 259996..262588 (-) 2593 Protein_255 penicillin-binding protein 1A -
  NYR89_RS01345 (NYR89_01340) - 262735..263415 (+) 681 WP_279446017.1 pilus assembly protein PilM -
  NYR89_RS01350 (NYR89_01345) - 263397..263918 (+) 522 WP_279446018.1 hypothetical protein -
  NYR89_RS01355 (NYR89_01350) - 263922..264449 (+) 528 WP_279446019.1 chromosome segregation protein -
  NYR89_RS01360 (NYR89_01355) - 264442..264846 (+) 405 WP_279446020.1 hypothetical protein -
  NYR89_RS01365 (NYR89_01360) comE 264856..266151 (+) 1296 WP_279446021.1 type IV pilus secretin PilQ Machinery gene
  NYR89_RS01370 (NYR89_01365) nusB 266277..266690 (+) 414 WP_279446022.1 transcription antitermination factor NusB -
  NYR89_RS01375 (NYR89_01370) thiL 266755..267721 (+) 967 Protein_262 thiamine-phosphate kinase -
  NYR89_RS01380 (NYR89_01375) - 267726..268199 (+) 474 WP_279446023.1 phosphatidylglycerophosphatase A -
  NYR89_RS01385 (NYR89_01380) - 268208..268834 (+) 627 WP_279446024.1 LysE family transporter -
  NYR89_RS01390 (NYR89_01385) - 268896..269994 (-) 1099 Protein_265 TrmH family RNA methyltransferase -
  NYR89_RS01395 (NYR89_01390) suhB 270161..270972 (+) 812 Protein_266 inositol-1-monophosphatase -

Sequence

Protein


Download         Length: 431 a.a.        Molecular weight: 48162.17 Da        Isoelectric Point: 9.3703

>NTDB_id=725795 NYR89_RS01365 WP_279446021.1 264856..266151(+) (comE) [Actinobacillus arthritidis strain CCUG24862]
MKRMILLLFFMFSSAYVYAFSISLRNAPTSEILSYLAEEYSKNIVLSDNIETNTTLRIENSDFDSVLKSITRSNKLTSAY
ENQIYFIGHKKDDKDPNRGLNPELLKPKLITKTIKLDYAKATEVIESLTKGSGNFLSENGYLHFDDRSNSLIIKDSPESM
KNIVKLIRNLDKPTEQIAIEARIVTISSENLQELGVRWGMFSPTNGHHKIAGSLEVNGLPDTNHLNVNFPVNNAASIALQ
VAKINGRVLDLELTALEQENDVEIIASPRLLTTNKKPASIKQGTEIPYVLYNRKDEVKNIEFKEAVLGLQVTPHISNDKQ
ILLDLVVTQNSPNSTSSTVHGLVTIDKQELNTQVFAQHGETIVLGGIFQHLTAKGEDRVPILGSIPFLKKLFSHSSNRVS
KRELVIFVTPYIVKSGKQKISSHSSHKLPPK

Nucleotide


Download         Length: 1296 bp        

>NTDB_id=725795 NYR89_RS01365 WP_279446021.1 264856..266151(+) (comE) [Actinobacillus arthritidis strain CCUG24862]
ATGAAAAGAATGATTTTGTTACTCTTTTTTATGTTTTCATCGGCTTACGTATATGCTTTTTCTATCTCGTTGAGGAATGC
ACCGACTTCAGAAATCCTGAGTTATTTGGCGGAAGAATACAGCAAAAATATTGTGTTAAGCGACAATATTGAAACGAATA
CCACGTTAAGAATTGAAAATAGTGATTTTGATAGTGTGTTAAAAAGTATCACTCGATCAAATAAGTTGACCAGTGCGTAT
GAAAACCAAATCTATTTTATTGGTCATAAAAAAGACGATAAGGATCCTAACAGGGGATTAAATCCGGAATTATTAAAACC
TAAATTGATTACTAAAACTATTAAGTTAGATTATGCCAAAGCAACGGAAGTGATTGAATCTTTAACTAAAGGTAGCGGTA
ATTTTTTATCAGAAAACGGTTATTTACATTTTGATGATCGCAGTAATAGCTTAATTATTAAAGATAGCCCGGAATCAATG
AAAAATATCGTAAAATTAATTAGAAATTTAGACAAACCGACCGAACAAATTGCGATTGAAGCGAGAATAGTCACAATAAG
CAGTGAGAATTTGCAAGAACTTGGGGTACGTTGGGGAATGTTTTCGCCGACAAATGGACATCATAAAATTGCCGGTTCTC
TTGAAGTGAATGGATTACCGGATACTAACCATTTAAACGTCAATTTTCCGGTAAATAACGCCGCTTCTATTGCGTTACAG
GTGGCTAAAATTAATGGACGCGTACTTGATTTGGAATTAACCGCTTTAGAACAAGAAAACGATGTAGAAATTATTGCCAG
CCCACGTTTACTGACTACCAATAAAAAACCGGCAAGTATTAAACAGGGAACTGAAATTCCATATGTACTTTATAACCGTA
AAGATGAAGTGAAAAATATCGAATTTAAAGAAGCCGTTTTAGGGCTACAAGTCACGCCGCATATTTCAAATGATAAGCAA
ATTTTGCTCGATCTAGTTGTGACACAAAATTCGCCAAATTCAACCAGTTCGACCGTGCATGGTTTAGTCACGATTGATAA
ACAGGAATTAAATACGCAAGTATTCGCTCAACATGGTGAAACCATTGTACTTGGCGGTATTTTTCAGCATTTAACCGCAA
AAGGTGAGGATAGAGTGCCAATTTTAGGTTCAATTCCGTTTCTTAAAAAATTATTTAGTCATTCCAGTAACAGAGTTAGT
AAGCGTGAGTTAGTCATTTTCGTTACACCTTATATTGTTAAAAGTGGAAAACAGAAAATTTCCTCTCATTCTTCACATAA
ATTACCGCCAAAATAA

Domains

Predicted by InterproScan.

Bacterial type II/III secretion system short domain (Secretin_N)

(111-176)

Bacterial type II and III secretion system protein (Secretin)

(255-414)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Glaesserella parasuis strain SC1401

64.988

96.752

0.629
  comE Haemophilus influenzae Rd KW20

54.975

93.271

0.513
  comE Haemophilus influenzae 86-028NP

54.591

93.503

0.51
  pilQ Vibrio campbellii strain DS40M4

41.981

98.376

0.413
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

42.754

96.056

0.411
  pilQ Vibrio cholerae strain A1552

42.754

96.056

0.411