Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   NYR73_RS06020 Genome accession   NZ_CP103818
Coordinates   1326731..1328029 (-) Length   432 a.a.
NCBI ID   WP_279452964.1    Uniprot ID   -
Organism   Actinobacillus equuli subsp. haemolyticus strain 3874     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1321731..1333029
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NYR73_RS05990 (NYR73_05995) suhB 1321904..1322716 (-) 813 WP_279436613.1 inositol-1-monophosphatase -
  NYR73_RS05995 (NYR73_06000) - 1322883..1323981 (+) 1099 Protein_1164 TrmH family RNA methyltransferase -
  NYR73_RS06000 (NYR73_06005) - 1324043..1324667 (-) 625 Protein_1165 LysE family transporter -
  NYR73_RS06005 (NYR73_06010) - 1324676..1325149 (-) 474 WP_279452961.1 phosphatidylglycerophosphatase A -
  NYR73_RS06010 (NYR73_06015) thiL 1325162..1326127 (-) 966 WP_279452962.1 thiamine-phosphate kinase -
  NYR73_RS06015 (NYR73_06020) nusB 1326192..1326605 (-) 414 WP_279452963.1 transcription antitermination factor NusB -
  NYR73_RS06020 (NYR73_06025) comE 1326731..1328029 (-) 1299 WP_279452964.1 type IV pilus secretin PilQ Machinery gene
  NYR73_RS06025 (NYR73_06030) - 1328040..1328444 (-) 405 WP_279436619.1 hypothetical protein -
  NYR73_RS06030 (NYR73_06035) - 1328437..1328796 (-) 360 WP_279452965.1 chromosome segregation protein -
  NYR73_RS06035 (NYR73_06040) - 1328967..1329488 (-) 522 WP_279436621.1 hypothetical protein -
  NYR73_RS06040 (NYR73_06045) - 1329470..1330156 (-) 687 WP_279436623.1 pilus assembly protein PilM -
  NYR73_RS06045 (NYR73_06050) - 1330295..1332880 (+) 2586 WP_279436624.1 penicillin-binding protein 1A -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 47690.77 Da        Isoelectric Point: 9.5571

>NTDB_id=725470 NYR73_RS06020 WP_279452964.1 1326731..1328029(-) (comE) [Actinobacillus equuli subsp. haemolyticus strain 3874]
MKKAILLLFFIFSSVTVYAFSISLKNAPTAEILSYLAEEHGKNIVLSDNIETNTTLRIENSDFDSVLKSITRANKLTTAY
ENQIYFIGHKKDEKAATPIAVNPDVLKPKLITKTIKLDYAKAAEVIGSLTKGSGNFLSENGYLHFDDRSNSLIIKDSPES
MKNIVKLIRNLDKPTEQIAIEARIVTISSENLQELGVRWGMFSPANGHHKIAGSLEANGLPNTNHLNVNFPVNNAASLAL
QVAKINGRVLDLELTALEQENNVEIIASPRLLTTNKKPASIKQGTEIPYVLYNRKDEVKNIEFKEAVLGLQVTPHISNDN
QILLDLVVTQNSPNSTSSTVHGLVTIDKQELNTQVFAKHGETIVLGGIFQHLTAKGEDRMPILGSIPVIKKLFSHSSDRI
SKRELVIFVTPYIVKSGKQQISSHSSQKLPPK

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=725470 NYR73_RS06020 WP_279452964.1 1326731..1328029(-) (comE) [Actinobacillus equuli subsp. haemolyticus strain 3874]
ATGAAGAAAGCGATTTTGTTACTCTTTTTTATATTTTCATCCGTTACTGTGTATGCATTTTCTATCTCGTTAAAAAATGC
ACCGACCGCAGAAATTCTGAGTTATTTAGCGGAAGAGCACGGAAAAAATATTGTGCTAAGCGACAATATTGAAACGAATA
CCACATTAAGAATTGAAAATAGTGATTTTGATAGTGTTTTAAAAAGTATCACTCGAGCGAATAAATTGACGACAGCATAT
GAGAACCAAATCTATTTTATTGGACACAAAAAAGATGAGAAAGCGGCTACGCCAATAGCTGTAAATCCGGATGTATTGAA
ACCTAAGTTGATTACTAAGACAATAAAATTAGATTATGCGAAGGCAGCGGAAGTGATTGGATCTTTAACCAAAGGTAGTG
GTAATTTTTTATCGGAAAACGGCTATCTACATTTTGATGATCGTAGTAATAGTTTGATAATTAAAGATAGCCCGGAATCG
ATGAAAAATATCGTGAAATTAATTAGAAATCTGGATAAACCGACTGAGCAGATTGCGATTGAAGCAAGGATAGTCACAAT
AAGTAGTGAAAATTTGCAAGAGCTTGGGGTACGCTGGGGAATGTTTTCTCCGGCAAACGGACATCATAAAATTGCCGGTT
CGCTTGAAGCAAATGGGCTACCGAATACTAATCATTTAAACGTAAATTTTCCGGTAAATAATGCTGCTTCACTTGCGCTA
CAAGTGGCAAAAATTAATGGGCGAGTGCTTGATTTGGAACTCACCGCTTTGGAACAAGAAAATAATGTAGAAATTATTGC
CAGCCCCCGTTTATTGACTACCAATAAGAAGCCGGCGAGTATTAAGCAAGGGACAGAAATTCCGTATGTGCTTTATAACC
GTAAAGATGAAGTGAAAAATATCGAATTTAAAGAAGCCGTTTTAGGGCTACAGGTCACGCCACATATTTCAAATGATAAT
CAAATTTTGCTTGATTTGGTGGTGACACAAAATTCGCCGAATTCAACCAGTTCGACAGTTCATGGTTTAGTAACGATTGA
TAAACAGGAATTAAATACGCAAGTATTCGCTAAGCATGGTGAAACTATAGTGCTAGGCGGTATTTTTCAGCATTTAACCG
CAAAAGGTGAGGACAGAATGCCGATTTTAGGTTCAATTCCGGTCATTAAAAAGTTATTTAGCCATTCCAGTGATAGGATC
AGTAAGCGCGAATTAGTTATTTTCGTTACACCTTATATTGTTAAAAGTGGAAAACAGCAAATTTCCTCGCATTCTTCACA
GAAATTACCGCCAAAATAG

Domains

Predicted by InterProScan.

Bacterial type II and III secretion system protein (Secretin)

(256-415)

Bacterial type II/III secretion system short domain (Secretin_N)

(112-177)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Glaesserella parasuis strain SC1401

66.268

96.759

0.641
  comE Haemophilus influenzae Rd KW20

55.583

93.287

0.519
  comE Haemophilus influenzae 86-028NP

55.198

93.519

0.516
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

42.892

96.065

0.412
  pilQ Vibrio cholerae strain A1552

42.892

96.065

0.412
  pilQ Vibrio campbellii strain DS40M4

40.995

97.685

0.4