Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   NYR64_RS05915 Genome accession   NZ_CP103810
Coordinates   1308104..1309399 (-) Length   431 a.a.
NCBI ID   WP_279436618.1    Uniprot ID   -
Organism   Actinobacillus equuli subsp. haemolyticus strain CCUG19799     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1303104..1314399
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NYR64_RS05885 (NYR64_05885) suhB 1303276..1304088 (-) 813 WP_279436613.1 inositol-1-monophosphatase -
  NYR64_RS05890 (NYR64_05890) - 1304255..1305352 (+) 1098 WP_279436614.1 TrmH family RNA methyltransferase -
  NYR64_RS05895 (NYR64_05895) - 1305414..1306040 (-) 627 WP_279436615.1 LysE family transporter -
  NYR64_RS05900 (NYR64_05900) - 1306049..1306522 (-) 474 WP_279436616.1 phosphatidylglycerophosphatase A -
  NYR64_RS05905 (NYR64_05905) thiL 1306535..1307500 (-) 966 WP_279436617.1 thiamine-phosphate kinase -
  NYR64_RS05910 (NYR64_05910) nusB 1307565..1307978 (-) 414 WP_278225876.1 transcription antitermination factor NusB -
  NYR64_RS05915 (NYR64_05915) comE 1308104..1309399 (-) 1296 WP_279436618.1 type IV pilus secretin PilQ Machinery gene
  NYR64_RS05920 (NYR64_05920) - 1309410..1309814 (-) 405 WP_279436619.1 hypothetical protein -
  NYR64_RS05925 (NYR64_05925) - 1309807..1310334 (-) 528 WP_279436620.1 chromosome segregation protein -
  NYR64_RS05930 (NYR64_05930) - 1310337..1310858 (-) 522 WP_279436621.1 hypothetical protein -
  NYR64_RS05935 (NYR64_05935) - 1310840..1311526 (-) 687 WP_279436623.1 pilus assembly protein PilM -
  NYR64_RS05940 (NYR64_05940) - 1311665..1314250 (+) 2586 WP_279436624.1 penicillin-binding protein 1A -

Sequence

Protein


Download         Length: 431 a.a.        Molecular weight: 47758.75 Da        Isoelectric Point: 8.9359

>NTDB_id=725258 NYR64_RS05915 WP_279436618.1 1308104..1309399(-) (comE) [Actinobacillus equuli subsp. haemolyticus strain CCUG19799]
MKKAILLLFFIFSSVTVYAFSISLKNAPTAEILSYLAEEHGKNIVLSDNIETNTTLRIENSDFDSVLKSITRANKLTTAY
ENQIYFIGHKKDEKAATIGVNSELLKPKLITKTIKLDYAKAAEVIESLTKGSGNFLSENGYLHFDDRSNSLIIKDSPESM
KNIVKLIRNLDKPTEQIAIEARIVTISSENLQELGVRWGMFSPTNGHHKVAGSLEANGLPNTNHLNVNFPVNNAASIALQ
VAKINGRVLDLELTALEQENDVEIIASPRLLTTNKKPASIKQGTEIPYVLYNRKDEVKNIEFKEAVLGLQVTPHISNDNQ
ILLDLVVTQNSPNSTSSTVHGLVTIDKQELNTQVFAKHGETIVLGGIFQHLTAKGEDRMPILGSIPVIKKLFSHSSDRIS
KRELVIFVTPYIVKSEKQQISSHSSQKLPPK

Nucleotide


Download         Length: 1296 bp        

>NTDB_id=725258 NYR64_RS05915 WP_279436618.1 1308104..1309399(-) (comE) [Actinobacillus equuli subsp. haemolyticus strain CCUG19799]
ATGAAGAAAGCGATTTTGTTACTCTTTTTTATATTTTCATCCGTTACTGTGTATGCATTTTCTATCTCGTTAAAAAATGC
ACCGACCGCAGAAATTCTGAGTTATTTAGCGGAAGAGCACGGAAAAAATATTGTGCTAAGCGACAATATTGAAACGAATA
CCACATTAAGAATTGAAAATAGTGATTTTGATAGTGTTTTAAAAAGTATCACTCGAGCGAATAAATTGACGACAGCATAT
GAGAACCAAATCTATTTTATTGGCCATAAAAAAGATGAAAAGGCTGCTACTATAGGCGTAAATTCTGAGTTGTTAAAGCC
CAAGCTCATTACTAAAACCATCAAATTAGATTATGCCAAAGCGGCGGAAGTGATTGAATCTTTAACCAAAGGCAGCGGAA
ACTTTTTATCGGAAAACGGCTATCTACATTTTGATGATCGTAGTAATAGTTTGATAATTAAAGATAGCCCAGAATCGATG
AAAAATATCGTGAAATTAATTAGAAATCTGGATAAACCGACTGAGCAGATTGCGATTGAAGCAAGGATAGTCACAATAAG
TAGTGAAAATTTGCAAGAGCTTGGGGTACGCTGGGGAATGTTTTCTCCGACAAACGGACATCATAAAGTCGCTGGTTCGC
TTGAAGCAAATGGACTACCGAATACTAACCATTTAAACGTAAATTTTCCGGTAAATAATGCTGCATCTATTGCGCTACAA
GTGGCAAAAATTAATGGACGAGTGCTTGATTTGGAATTAACCGCTTTAGAGCAAGAAAATGATGTGGAAATTATTGCCAG
CCCTCGTTTACTGACCACTAATAAGAAACCGGCGAGTATTAAGCAAGGGACTGAAATTCCGTATGTGCTTTATAACCGTA
AAGATGAAGTGAAAAATATCGAATTTAAAGAAGCCGTTTTAGGGCTACAGGTCACGCCACATATTTCAAATGATAATCAA
ATTTTGCTTGATTTGGTGGTGACACAAAATTCGCCGAATTCAACCAGTTCGACAGTTCATGGTTTAGTAACGATTGATAA
ACAGGAATTAAATACGCAAGTATTCGCTAAGCATGGTGAAACTATTGTGCTAGGCGGTATTTTTCAGCATTTAACCGCAA
AAGGTGAGGACAGAATGCCGATTTTAGGTTCAATTCCGGTCATTAAAAAGTTATTTAGCCATTCCAGTGATAGGATCAGT
AAGCGCGAATTAGTTATTTTCGTTACACCTTATATTGTTAAAAGTGAAAAACAGCAAATTTCCTCGCATTCTTCACAGAA
ATTACCGCCAAAATAG

Domains

Predicted by InterProScan.

Bacterial type II and III secretion system protein (Secretin)

(255-414)

Bacterial type II/III secretion system short domain (Secretin_N)

(111-176)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Glaesserella parasuis strain SC1401

66.906

96.752

0.647
  comE Haemophilus influenzae Rd KW20

56.25

92.807

0.522
  comE Haemophilus influenzae 86-028NP

55.86

93.039

0.52
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

43.237

96.056

0.415
  pilQ Vibrio cholerae strain A1552

43.237

96.056

0.415
  pilQ Vibrio campbellii strain DS40M4

41.943

97.912

0.411