Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   NYR62_RS01065 Genome accession   NZ_CP103809
Coordinates   230391..231686 (+) Length   431 a.a.
NCBI ID   WP_279475933.1    Uniprot ID   -
Organism   Actinobacillus genomosp. 1 strain CCUG22229     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 225391..236686
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NYR62_RS01040 (NYR62_01040) - 225564..228131 (-) 2568 WP_279475929.1 penicillin-binding protein 1A -
  NYR62_RS01045 (NYR62_01045) - 228270..228950 (+) 681 WP_279475930.1 pilus assembly protein PilM -
  NYR62_RS01050 (NYR62_01050) - 228932..229453 (+) 522 WP_279475931.1 hypothetical protein -
  NYR62_RS01055 (NYR62_01055) - 229553..229984 (+) 432 WP_279476677.1 chromosome segregation protein -
  NYR62_RS01060 (NYR62_01060) - 229977..230381 (+) 405 WP_279475932.1 hypothetical protein -
  NYR62_RS01065 (NYR62_01065) comE 230391..231686 (+) 1296 WP_279475933.1 type IV pilus secretin PilQ Machinery gene
  NYR62_RS01070 (NYR62_01070) nusB 231812..232225 (+) 414 WP_279457768.1 transcription antitermination factor NusB -
  NYR62_RS01075 (NYR62_01075) thiL 232289..233257 (+) 969 WP_279475934.1 thiamine-phosphate kinase -
  NYR62_RS01080 (NYR62_01080) - 233262..233735 (+) 474 WP_279475936.1 phosphatidylglycerophosphatase A -
  NYR62_RS01085 (NYR62_01085) - 233744..234370 (+) 627 WP_279475938.1 LysE family transporter -
  NYR62_RS01090 (NYR62_01090) - 234432..235529 (-) 1098 WP_279475939.1 TrmH family RNA methyltransferase -
  NYR62_RS01095 (NYR62_01095) suhB 235696..236508 (+) 813 WP_279457772.1 inositol-1-monophosphatase -

Sequence

Protein


Download         Length: 431 a.a.        Molecular weight: 47777.80 Da        Isoelectric Point: 8.3506

>NTDB_id=725218 NYR62_RS01065 WP_279475933.1 230391..231686(+) (comE) [Actinobacillus genomosp. 1 strain CCUG22229]
MKRMILLLFFMLSSVIAHAFSISLKNAPTAEILSYLAEEYGKNIVLSDNIETNTTLRIENSDFDSVLKSITRANKLTSAY
ENQIYFISHKKDERATSVGVDAELLKPKLITKTIKLDYAKAAEVIESLTKGSGHFLSENGYLHFDDRSNSLIIKDSPESM
KNIVKLIRNLDKPTEQIAIEARIVTISSENLQELGVRWGIFSPANGHHKIAGSLEANGLPNTNRLNVNFPVNNAASIALQ
VAKINGRVLDLELTALEQENDVEIIASPRLLTTNKKPASIKQGTEIPYVLYNRKDEVKNIEFKEAVLGLQVTPHISNDNQ
ILLDLIVTQNSPNSAASTINGLVTIDKQELNTQVFAQHGETIVLGGIFQHLAAKGEDRVPILGSIPVLKKLFSHSSDRIS
KRELVIFVTPYIVKNEKQQISSHSSQKLPPK

Nucleotide


Download         Length: 1296 bp        

>NTDB_id=725218 NYR62_RS01065 WP_279475933.1 230391..231686(+) (comE) [Actinobacillus genomosp. 1 strain CCUG22229]
ATGAAAAGAATGATTTTGCTACTCTTTTTTATGTTGTCCTCTGTGATTGCACATGCTTTTTCTATTTCATTAAAAAATGC
GCCGACAGCAGAAATTTTAAGCTACTTAGCCGAAGAGTACGGCAAAAATATTGTGTTAAGCGACAATATTGAAACGAATA
CCACCTTAAGGATTGAAAATAGCGATTTTGATAGTGTGCTAAAAAGTATTACTCGAGCAAATAAGCTGACCAGTGCCTAT
GAAAATCAGATCTATTTTATTAGCCATAAAAAAGATGAAAGAGCTACTAGCGTAGGCGTAGATGCTGAATTGTTAAAGCC
TAAGTTAATTACTAAAACCATCAAGTTAGATTATGCCAAAGCGGCGGAAGTAATTGAATCTTTAACCAAAGGTAGCGGTC
ATTTTTTATCGGAAAACGGTTATTTGCATTTTGATGATCGTAGTAATAGTTTGATCATTAAAGATAGTCCGGAATCAATG
AAAAATATCGTGAAATTAATTAGAAATTTGGATAAGCCGACCGAGCAAATTGCGATTGAAGCGAGAATTGTCACGATAAG
TAGTGAGAATTTACAAGAGTTAGGCGTACGCTGGGGGATATTTTCTCCGGCAAACGGACATCATAAAATTGCCGGTTCGC
TTGAAGCGAATGGACTACCGAATACTAACCGTTTAAACGTAAATTTTCCGGTAAATAATGCTGCTTCTATTGCGTTACAA
GTGGCTAAAATTAATGGTCGTGTGCTTGATTTGGAATTAACCGCTTTAGAGCAGGAAAATGATGTGGAAATTATTGCCAG
TCCTCGTTTGCTGACCACCAATAAGAAGCCGGCAAGTATTAAGCAAGGGACGGAAATTCCTTATGTGTTATATAACCGTA
AAGATGAAGTGAAAAATATTGAATTTAAAGAAGCGGTTTTAGGCTTGCAAGTGACACCGCATATTTCAAACGATAATCAG
ATTTTGCTCGATCTGATAGTGACGCAAAATTCACCGAATTCCGCCGCTTCAACAATTAATGGTTTAGTGACGATTGATAA
ACAAGAACTCAATACGCAAGTATTTGCTCAGCATGGTGAAACCATTGTACTTGGTGGTATTTTTCAACATTTAGCCGCAA
AAGGAGAGGACAGAGTCCCTATTTTAGGTTCAATTCCGGTACTTAAAAAATTATTTAGCCATTCCAGTGATAGGATCAGT
AAGCGCGAATTAGTTATTTTCGTTACGCCTTATATCGTCAAAAACGAAAAACAGCAAATTTCCTCGCATTCTTCACAGAA
ATTACCGCCAAAATAG

Domains

Predicted by InterproScan.

Bacterial type II and III secretion system protein (Secretin)

(255-414)

Bacterial type II/III secretion system short domain (Secretin_N)

(111-176)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Glaesserella parasuis strain SC1401

66.587

96.52

0.643
  comE Haemophilus influenzae Rd KW20

55.89

92.575

0.517
  comE Haemophilus influenzae 86-028NP

55.5

92.807

0.515
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

42.892

96.288

0.413
  pilQ Vibrio cholerae strain A1552

42.892

96.288

0.413
  pilQ Vibrio campbellii strain DS40M4

42.043

97.68

0.411