Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   NYR61_RS01040 Genome accession   NZ_CP103808
Coordinates   227081..228376 (+) Length   431 a.a.
NCBI ID   WP_279468945.1    Uniprot ID   -
Organism   Actinobacillus genomosp. 1 strain CCUG22231     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 222081..233376
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NYR61_RS01015 (NYR61_01015) - 222254..224821 (-) 2568 WP_279468941.1 penicillin-binding protein 1A -
  NYR61_RS01020 (NYR61_01020) - 224960..225640 (+) 681 WP_279468942.1 pilus assembly protein PilM -
  NYR61_RS01025 (NYR61_01025) - 225622..226143 (+) 522 WP_279468943.1 hypothetical protein -
  NYR61_RS01030 (NYR61_01030) - 226243..226674 (+) 432 WP_279469498.1 chromosome segregation protein -
  NYR61_RS01035 (NYR61_01035) - 226667..227071 (+) 405 WP_279468944.1 hypothetical protein -
  NYR61_RS01040 (NYR61_01040) comE 227081..228376 (+) 1296 WP_279468945.1 type IV pilus secretin PilQ Machinery gene
  NYR61_RS01045 (NYR61_01045) nusB 228502..228915 (+) 414 WP_279457768.1 transcription antitermination factor NusB -
  NYR61_RS01050 (NYR61_01050) thiL 228979..229947 (+) 969 WP_279468946.1 thiamine-phosphate kinase -
  NYR61_RS01055 (NYR61_01055) - 229957..230430 (+) 474 WP_279457770.1 phosphatidylglycerophosphatase A -
  NYR61_RS01060 (NYR61_01060) - 230443..231066 (+) 624 WP_279469499.1 LysE family transporter -
  NYR61_RS01065 (NYR61_01065) - 231128..232225 (-) 1098 WP_279468947.1 TrmH family RNA methyltransferase -
  NYR61_RS01070 (NYR61_01070) suhB 232392..233204 (+) 813 WP_279457772.1 inositol-1-monophosphatase -

Sequence

Protein


Download         Length: 431 a.a.        Molecular weight: 47776.82 Da        Isoelectric Point: 8.9503

>NTDB_id=725191 NYR61_RS01040 WP_279468945.1 227081..228376(+) (comE) [Actinobacillus genomosp. 1 strain CCUG22231]
MKRMILLLFFMLSSVIAHAFSISLKNAPTAEILSYLAEEYGKNIVLSDNIETNTTLRIENSDFDSVLKSITRANKLSSAY
ENQIYFIGHKKDERTTSVGLNAELLKPKLITKTIKLDYAKAAEVIESLTKGSGHFLSENGYLHFDDRSNSLIIKDSPESM
KNIVKLIRNLDKPTEQIAIEARIVTISSENLQELGVRWGIFSPANGHHKIAGSLEANGLPNTNRLNVNFPVNNAASIALQ
VAKINGRVLDLELTALEQENDVEIIASPRLLTTNKKPASIKQGTEIPYVLYNRKDEVKNIEFKEAVLGLQVTPHISNDNQ
ILLDLIVTQNSPNSAASTINGLVTIDKQELNTQVFAQHGETIVLGGIFQHLAAKGEDRVPILGSIPVLKKLFSHSSDRIS
KRELVIFVTPYIVKNEKQQISSHSSQKLPPK

Nucleotide


Download         Length: 1296 bp        

>NTDB_id=725191 NYR61_RS01040 WP_279468945.1 227081..228376(+) (comE) [Actinobacillus genomosp. 1 strain CCUG22231]
ATGAAAAGAATGATTTTGCTACTCTTTTTTATGTTGTCCTCTGTGATTGCACATGCTTTTTCTATTTCATTAAAAAATGC
GCCGACAGCAGAAATTTTAAGCTACTTAGCCGAAGAGTACGGCAAAAATATTGTGTTAAGCGACAATATTGAAACAAATA
CCACCTTAAGGATTGAAAATAGCGATTTTGATAGTGTGTTAAAAAGTATTACTCGAGCGAATAAGCTCAGTAGTGCCTAT
GAAAATCAGATCTATTTTATTGGTCATAAAAAAGATGAAAGAACTACTAGTGTAGGCTTAAATGCTGAATTGTTAAAACC
TAAGTTAATTACTAAAACCATCAAGTTAGATTATGCTAAGGCGGCGGAAGTAATTGAATCTTTAACCAAAGGTAGCGGTC
ATTTTTTATCGGAAAACGGTTATTTGCATTTTGATGATCGCAGTAATAGTTTGATCATTAAAGATAGTCCGGAATCAATG
AAAAATATCGTGAAATTAATTAGAAATTTGGATAAGCCGACCGAGCAAATTGCGATTGAAGCGAGAATTGTCACGATAAG
TAGTGAGAATTTACAAGAGTTAGGCGTACGCTGGGGGATATTTTCTCCGGCAAACGGACATCATAAAATTGCCGGTTCGC
TTGAAGCGAATGGACTACCGAATACTAACCGTTTAAACGTAAATTTTCCGGTAAATAATGCTGCTTCTATTGCGTTACAA
GTGGCTAAAATTAATGGTCGTGTGCTTGATTTGGAATTAACCGCTTTAGAGCAGGAAAATGATGTGGAAATTATTGCCAG
TCCTCGTTTGCTGACCACCAATAAGAAGCCGGCAAGTATTAAGCAAGGGACGGAAATTCCTTATGTGTTATATAACCGTA
AAGATGAAGTGAAAAATATTGAATTTAAAGAAGCGGTTTTAGGCTTGCAAGTGACACCGCATATTTCAAACGATAATCAG
ATTTTACTCGATCTGATAGTGACGCAAAATTCACCGAATTCAGCCGCTTCAACAATTAATGGTTTAGTGACGATTGATAA
ACAAGAACTCAATACGCAAGTATTTGCTCAGCATGGTGAAACCATTGTACTTGGTGGTATTTTTCAACATTTAGCCGCAA
AAGGAGAGGACAGAGTCCCTATTTTAGGTTCAATTCCGGTACTTAAAAAATTATTTAGCCATTCGAGTGATAGAATCAGT
AAGCGCGAATTAGTTATTTTCGTTACGCCTTATATCGTCAAAAACGAAAAACAGCAAATTTCCTCGCATTCTTCACAGAA
ATTACCGCCAAAATAG

Domains

Predicted by InterproScan.

Bacterial type II and III secretion system protein (Secretin)

(255-414)

Bacterial type II/III secretion system short domain (Secretin_N)

(111-176)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Glaesserella parasuis strain SC1401

66.986

96.984

0.65
  comE Haemophilus influenzae Rd KW20

55.89

92.575

0.517
  comE Haemophilus influenzae 86-028NP

55.362

93.039

0.515
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

42.995

96.056

0.413
  pilQ Vibrio cholerae strain A1552

42.995

96.056

0.413
  pilQ Vibrio campbellii strain DS40M4

41.371

98.144

0.406