Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   NYR60_RS01025 Genome accession   NZ_CP103807
Coordinates   210920..212215 (+) Length   431 a.a.
NCBI ID   WP_279467230.1    Uniprot ID   -
Organism   Actinobacillus genomosp. 2 strain CCUG15571     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 205920..217215
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NYR60_RS01000 (NYR60_01000) - 206048..208660 (-) 2613 WP_279467222.1 penicillin-binding protein 1A -
  NYR60_RS01005 (NYR60_01005) - 208799..209479 (+) 681 WP_279467224.1 pilus assembly protein PilM -
  NYR60_RS01010 (NYR60_01010) - 209461..209982 (+) 522 WP_279467226.1 hypothetical protein -
  NYR60_RS01015 (NYR60_01015) - 209986..210513 (+) 528 WP_279467227.1 chromosome segregation protein -
  NYR60_RS01020 (NYR60_01020) - 210506..210910 (+) 405 WP_279467228.1 hypothetical protein -
  NYR60_RS01025 (NYR60_01025) comE 210920..212215 (+) 1296 WP_279467230.1 type IV pilus secretin PilQ Machinery gene
  NYR60_RS01030 (NYR60_01030) nusB 212345..212758 (+) 414 WP_279467232.1 transcription antitermination factor NusB -
  NYR60_RS01035 (NYR60_01035) thiL 212823..213788 (+) 966 WP_279467233.1 thiamine-phosphate kinase -
  NYR60_RS01040 (NYR60_01040) - 213801..214274 (+) 474 WP_279467235.1 phosphatidylglycerophosphatase A -
  NYR60_RS01045 (NYR60_01045) - 214283..214908 (+) 626 Protein_201 LysE family transporter -
  NYR60_RS01050 (NYR60_01050) - 214966..216063 (-) 1098 WP_279467237.1 TrmH family RNA methyltransferase -
  NYR60_RS01055 (NYR60_01055) suhB 216230..217042 (+) 813 WP_279436613.1 inositol-1-monophosphatase -

Sequence

Protein


Download         Length: 431 a.a.        Molecular weight: 48000.08 Da        Isoelectric Point: 8.9967

>NTDB_id=725171 NYR60_RS01025 WP_279467230.1 210920..212215(+) (comE) [Actinobacillus genomosp. 2 strain CCUG15571]
MKRMILLLFFMFSSACVYAFSISLRNAPTSEILSYLAEEYSKNIVLSDNIETNTTLRIENSDFDSVLKSITRVNKLTSTY
ENQIYFIGHKKDDKDPNRGLNPELLKPKLITKTIKLDYAKAAEVIESLTKGSGNFLSENGYLHFDDRSNSLIIKDSPESM
KNIVKLIKNLDKPTEQIAIEARIVTISSENLQELGVRWGMFSPANGHHKVAGSLEVNGLPDTNHLNVNFPVNNAASIALQ
VAKINGRVLDLELTALEQENDVEIIASPRLLTTNKKPASIKQGTEIPYVLYNRKDEVKNIEFKEAVLGLQVTPHISNDKQ
ILLDLVVTQNSPNSTSSTVHGLVTIDKQELNTQVFAQHGETIVLGGIFQHLTAKGEDRVPILGSIPVIKKLFSHSSDRIS
KRELVIFVTPYIVKSGKQKISSHSSQKLPPK

Nucleotide


Download         Length: 1296 bp        

>NTDB_id=725171 NYR60_RS01025 WP_279467230.1 210920..212215(+) (comE) [Actinobacillus genomosp. 2 strain CCUG15571]
ATGAAAAGAATGATTTTGTTACTCTTTTTTATGTTTTCATCGGCTTGCGTATATGCTTTTTCTATCTCATTGAGGAATGC
ACCGACTTCAGAAATCCTGAGTTATTTGGCGGAAGAATACAGCAAAAATATTGTGTTAAGCGACAATATTGAAACGAATA
CCACGTTAAGAATTGAAAATAGTGATTTTGATAGTGTGTTAAAAAGTATTACTCGAGTAAATAAGCTGACGAGTACGTAT
GAAAACCAAATCTATTTTATTGGTCATAAAAAAGACGATAAGGATCCTAACAGGGGATTAAATCCGGAATTATTAAAACC
TAAATTGATTACTAAGACAATAAAATTAGATTATGCCAAAGCAGCGGAAGTGATTGAATCTTTAACTAAAGGTAGCGGTA
ATTTTTTATCGGAAAACGGCTATTTACATTTTGATGATCGCAGTAATAGCTTAATTATTAAAGATAGCCCAGAATCGATG
AAAAATATTGTGAAATTAATCAAAAATTTAGACAAACCGACCGAACAAATTGCGATTGAAGCAAGGATAGTCACAATAAG
TAGTGAAAATTTGCAAGAGCTTGGGGTACGTTGGGGAATGTTTTCTCCGGCAAATGGACATCATAAAGTCGCTGGTTCGC
TTGAAGTGAATGGATTACCGGATACTAACCATTTAAATGTCAATTTTCCGGTAAATAACGCTGCTTCTATTGCGTTACAG
GTGGCTAAAATTAATGGACGTGTACTTGATTTGGAATTAACCGCTTTAGAACAAGAAAACGATGTAGAAATTATTGCCAG
CCCACGTTTACTGACTACCAATAAAAAACCGGCAAGTATTAAACAGGGGACTGAAATTCCATATGTGCTTTATAACCGTA
AAGATGAAGTGAAAAATATCGAATTTAAAGAAGCCGTTTTAGGGCTACAAGTCACGCCGCATATTTCAAATGATAAGCAA
ATTTTGCTTGATTTGGTAGTTACACAAAATTCACCGAATTCAACCAGTTCAACCGTGCATGGTTTAGTTACGATTGATAA
ACAGGAATTAAATACGCAAGTATTCGCTCAACATGGTGAAACCATTGTACTTGGCGGTATTTTTCAGCATTTAACCGCAA
AAGGTGAGGATAGAGTGCCAATTTTAGGCTCAATTCCGGTCATTAAAAAATTATTTAGCCATTCCAGTGATAGGATAAGT
AAGCGTGAGTTAGTCATTTTCGTTACACCTTATATTGTTAAAAGTGGAAAACAGAAAATTTCCTCGCATTCTTCACAGAA
ATTACCGCCAAAATAG

Domains

Predicted by InterproScan.

Bacterial type II and III secretion system protein (Secretin)

(255-414)

Bacterial type II/III secretion system short domain (Secretin_N)

(111-176)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Glaesserella parasuis strain SC1401

65.947

96.752

0.638
  comE Haemophilus influenzae Rd KW20

52.656

100

0.529
  comE Haemophilus influenzae 86-028NP

52.425

100

0.527
  pilQ Vibrio campbellii strain DS40M4

41.981

98.376

0.413
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

42.995

96.056

0.413
  pilQ Vibrio cholerae strain A1552

42.995

96.056

0.413