Detailed information
Bioinformatically predicted
Overview
| Name | dprA | Type | Machinery gene |
| Locus tag | M5R22_RS02195 | Genome accession | NZ_CP103742 |
| Coordinates | 451398..452522 (+) | Length | 374 a.a. |
| NCBI ID | WP_134355248.1 | Uniprot ID | - |
| Organism | Escherichia coli O25b:H4-ST131 strain 2822 | ||
| Function | ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing |
||
Genomic Context
Location: 446398..457522
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| M5R22_RS02170 (M5R22_02170) | mscL | 446515..446928 (-) | 414 | WP_000022450.1 | large-conductance mechanosensitive channel protein MscL | - |
| M5R22_RS02175 (M5R22_02175) | trkA | 447058..448434 (-) | 1377 | WP_000691382.1 | Trk system potassium transporter TrkA | - |
| M5R22_RS02180 (M5R22_02180) | rsmB | 448456..449745 (-) | 1290 | WP_000744765.1 | 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB | - |
| M5R22_RS02185 (M5R22_02185) | fmt | 449797..450744 (-) | 948 | WP_000004421.1 | methionyl-tRNA formyltransferase | - |
| M5R22_RS02190 (M5R22_02190) | def | 450759..451268 (-) | 510 | WP_000114984.1 | peptide deformylase | - |
| M5R22_RS02195 (M5R22_02195) | dprA | 451398..452522 (+) | 1125 | WP_134355248.1 | DNA-protecting protein DprA | Machinery gene |
| M5R22_RS02200 (M5R22_02200) | smg | 452494..452967 (+) | 474 | WP_000460673.1 | DUF494 family protein Smg | - |
| M5R22_RS02205 (M5R22_02205) | yrdD | 452996..453538 (+) | 543 | WP_001296461.1 | type I DNA topoisomerase | - |
| M5R22_RS02210 (M5R22_02210) | tsaC | 453543..454115 (+) | 573 | WP_001296460.1 | L-threonylcarbamoyladenylate synthase type 1 TsaC | - |
| M5R22_RS02215 (M5R22_02215) | aroE | 454120..454938 (+) | 819 | WP_000451255.1 | shikimate dehydrogenase | - |
| M5R22_RS02220 (M5R22_02220) | yrdB | 454935..455192 (+) | 258 | WP_001070565.1 | DUF1488 domain-containing protein | - |
| M5R22_RS02225 (M5R22_02225) | yrdA | 455168..455722 (-) | 555 | WP_000005712.1 | gamma carbonic anhydrase family protein | - |
Sequence
Protein
Download Length: 374 a.a. Molecular weight: 40876.84 Da Isoelectric Point: 6.0395
>NTDB_id=724441 M5R22_RS02195 WP_134355248.1 451398..452522(+) (dprA) [Escherichia coli O25b:H4-ST131 strain 2822]
MVDTEIWLRLMSISSLYGDDMVRIAHWLAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
LYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHAPLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV
MVDTEIWLRLMSISSLYGDDMVRIAHWLAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
LYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHAPLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV
Nucleotide
Download Length: 1125 bp
>NTDB_id=724441 M5R22_RS02195 WP_134355248.1 451398..452522(+) (dprA) [Escherichia coli O25b:H4-ST131 strain 2822]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGCATCAGCAGCTTGTATGGCGATGATATGGTCCGTATAGCTCACTG
GCTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTATATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGTTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT
GGCGTTAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGCCATGCTCCACTGGCTGCCAGTCTACT
TGAGCAAGGTGGTGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAGGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGTGAAGTTTTTGCTTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGCATCAGCAGCTTGTATGGCGATGATATGGTCCGTATAGCTCACTG
GCTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTATATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGTTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT
GGCGTTAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGCCATGCTCCACTGGCTGCCAGTCTACT
TGAGCAAGGTGGTGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAGGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGTGAAGTTTTTGCTTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| dprA | Vibrio campbellii strain DS40M4 |
49.051 |
98.663 |
0.484 |
| dprA | Vibrio cholerae strain A1552 |
49.677 |
82.888 |
0.412 |
| dprA | Glaesserella parasuis strain SC1401 |
44.807 |
90.107 |
0.404 |
| dprA | Haemophilus influenzae Rd KW20 |
43.917 |
90.107 |
0.396 |
| dprA | Legionella pneumophila strain ERS1305867 |
44.242 |
88.235 |
0.39 |