Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   EKM74_RS15395 Genome accession   NZ_AP019306
Coordinates   2890462..2891334 (+) Length   290 a.a.
NCBI ID   WP_000593194.1    Uniprot ID   A0A9P3DKN4
Organism   Staphylococcus aureus strain TUM9463     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 2885462..2896334
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EKM74_RS15375 sucC 2885576..2886742 (+) 1167 WP_001020801.1 ADP-forming succinate--CoA ligase subunit beta -
  EKM74_RS15380 sucD 2886764..2887672 (+) 909 WP_000110253.1 succinate--CoA ligase subunit alpha -
  EKM74_RS15385 - 2887899..2889017 (+) 1119 WP_001041666.1 LysM peptidoglycan-binding domain-containing protein -
  EKM74_RS15390 fmhC 2889045..2890289 (+) 1245 WP_000672869.1 FemA/FemB family glycyltransferase FmhC -
  EKM74_RS15395 dprA 2890462..2891334 (+) 873 WP_000593194.1 DNA-processing protein DprA Machinery gene
  EKM74_RS15400 topA 2891508..2893583 (+) 2076 WP_001557331.1 type I DNA topoisomerase -
  EKM74_RS15405 trmFO 2893739..2895046 (+) 1308 WP_000195254.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -

Sequence

Protein


Download         Length: 290 a.a.        Molecular weight: 33541.01 Da        Isoelectric Point: 9.5093

>NTDB_id=72323 EKM74_RS15395 WP_000593194.1 2890462..2891334(+) (dprA) [Staphylococcus aureus strain TUM9463]
MIKLFLLKLYWAHFSTKQIHQFLMAYPNVIKEEGRKKDSYLCEWVNREENVLLLRKYYAFIKLDHNDIIKELQKLKVSYI
TYMDSEYPVLLKEIYQFPLLLFYKGNIKLINNMHHLAVVGARDSTSYTQQSLEFLLSNDKSKYLTIVSGLAQGADAMAHQ
IALKYNLPTIAVLAFGHQTHYPKSTLALRNKIEEKGLVISEYPPHTPIAKYRFPERNRIISGLSKGVLITEAKEQSGSHI
TIDFALEQNRNVYVLPGSMFNPMTKGNLLRIQEGAKVVLNANDIFEDYYI

Nucleotide


Download         Length: 873 bp        

>NTDB_id=72323 EKM74_RS15395 WP_000593194.1 2890462..2891334(+) (dprA) [Staphylococcus aureus strain TUM9463]
TTGATTAAACTATTTTTGCTTAAGTTATACTGGGCACACTTTTCGACTAAACAAATTCATCAATTTTTAATGGCATATCC
TAATGTAATTAAAGAGGAGGGAAGAAAAAAAGATAGTTATTTATGTGAATGGGTGAATAGGGAAGAAAATGTTCTTTTAT
TACGTAAATACTATGCTTTTATAAAACTTGATCATAACGATATTATTAAAGAACTGCAGAAATTAAAAGTAAGTTACATT
ACATATATGGATTCTGAATACCCAGTGCTATTAAAAGAAATATATCAATTTCCATTACTTCTTTTCTATAAAGGGAACAT
CAAATTAATAAATAATATGCATCATTTGGCAGTAGTAGGTGCAAGAGATTCTACAAGTTATACCCAACAGTCTTTAGAAT
TTTTATTATCAAATGATAAAAGCAAATATTTAACAATTGTTTCCGGCCTTGCTCAAGGAGCTGATGCAATGGCACATCAA
ATAGCTTTAAAATACAATCTCCCTACAATTGCAGTTTTAGCCTTTGGCCATCAAACACATTATCCCAAAAGTACATTAGC
ATTAAGAAATAAAATAGAAGAAAAAGGTTTAGTTATATCCGAATATCCACCACATACACCAATTGCTAAATATAGATTTC
CTGAGCGCAATAGAATTATCAGCGGTTTGTCAAAAGGGGTTTTAATTACTGAGGCTAAGGAACAAAGTGGCAGTCACATC
ACGATAGATTTTGCATTAGAGCAAAATAGAAATGTTTATGTTTTACCTGGATCTATGTTTAATCCTATGACAAAAGGTAA
TTTATTACGTATCCAAGAAGGTGCTAAGGTAGTATTAAACGCTAATGATATATTTGAAGACTACTATATTTAA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(72-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Staphylococcus aureus N315

100

100

1
  dprA Staphylococcus aureus MW2

99.655

100

0.997
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

37.809

97.586

0.369
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

37.809

97.586

0.369
  dprA/cilB/dalA Streptococcus pneumoniae D39

37.809

97.586

0.369
  dprA/cilB/dalA Streptococcus pneumoniae R6

37.809

97.586

0.369
  dprA/cilB/dalA Streptococcus mitis SK321

37.456

97.586

0.366

Multiple sequence alignment