Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   PVK48_RS07745 Genome accession   NZ_CP118307
Coordinates   1500522..1501304 (-) Length   260 a.a.
NCBI ID   WP_397610631.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain 20200554     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1495522..1506304
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PVK48_RS07720 (PVK48_07665) gatB 1495619..1497058 (-) 1440 WP_002988563.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -
  PVK48_RS07725 (PVK48_07670) gatA 1497058..1498524 (-) 1467 WP_002988562.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
  PVK48_RS07730 (PVK48_07675) gatC 1498524..1498826 (-) 303 WP_002988561.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  PVK48_RS07735 (PVK48_07680) - 1499058..1499282 (-) 225 WP_002988560.1 putative PEP-binding protein -
  PVK48_RS07740 (PVK48_07685) - 1499821..1500375 (-) 555 WP_002988559.1 cysteine hydrolase family protein -
  PVK48_RS07745 (PVK48_07690) codY 1500522..1501304 (-) 783 WP_397610631.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  PVK48_RS07750 (PVK48_07695) - 1501522..1502736 (-) 1215 WP_002988558.1 pyridoxal phosphate-dependent aminotransferase -
  PVK48_RS07755 (PVK48_07700) - 1502967..1503419 (+) 453 WP_002983265.1 universal stress protein -
  PVK48_RS07760 (PVK48_07705) - 1503542..1504930 (-) 1389 WP_002988557.1 Cof-type HAD-IIB family hydrolase -
  PVK48_RS07765 (PVK48_07710) - 1505002..1505967 (+) 966 WP_002983258.1 asparaginase -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 28661.82 Da        Isoelectric Point: 4.5611

>NTDB_id=721759 PVK48_RS07745 WP_397610631.1 1500522..1501304(-) (codY) [Streptococcus pyogenes strain 20200554]
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV
KAASRVYDTEANLSVENELTIFPVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEISSTVVGIQLLN
LQTENLEDTIRKQTAVNMAINTLSYSEMKVVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFAKLKEF

Nucleotide


Download         Length: 783 bp        

>NTDB_id=721759 PVK48_RS07745 WP_397610631.1 1500522..1501304(-) (codY) [Streptococcus pyogenes strain 20200554]
ATGCCTAACTTATTAGAAAAAACTCGTAAAATCACATCTATTTTGCAGCGTTCCGTAGATAGCCTAGAAACAGAATTACC
GTATAACACAATGGCATCTCGCCTAGCAGATATCATTGACTGCAATGCTTGTATTATCAATGGCGGCGGCACACTGCTTG
GTTATGCCATGAAATATAAAACTAACACTGATCGTGTTGAGGAATTTTTTGAAGCTAAACAATTTCCAGATACTTATGTA
AAGGCTGCTAGCCGAGTTTACGATACAGAAGCTAACCTTTCTGTCGAAAATGAATTGACTATATTCCCTGTTGAGTCTAA
AGACACTTATCCAGGAGGTCTAACGACTATTGCGCCGATTTATGGTGGAGGGATGCGCCTTGGATCACTCATTATCTGGC
GTAATGACAATGAGTTTAGTGATGATGATTTGATTTTGGTTGAGATCTCAAGTACTGTTGTGGGGATTCAACTATTAAAT
CTTCAGACAGAAAACTTAGAAGACACCATCCGTAAACAAACAGCGGTCAACATGGCAATTAATACGCTTTCTTATTCAGA
AATGAAAGTTGTTGCAGCAATTCTTGGAGAGTTAGATGGTAACGAAGGACGATTGACAGCTTCTGTTATTGCTGATCGTA
TTGGTATTACCCGTTCTGTTATTGTCAATGCTCTGCGTAAATTAGAAAGTGCAGGGATTATTGAAAGTCGTTCTCTTGGT
ATGAAAGGGACATACCTCAAAGTTATCAACGAAGGTATTTTTGCTAAATTAAAAGAATTTTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-260)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

65.759

98.846

0.65
  codY Bacillus subtilis subsp. subtilis str. 168

50.98

98.077

0.5