Detailed information NTG0072155

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: ST1232TP_RS06110
• Genome accession: NZ_AP024311
• Coordinates: 1261707..1262480 (+)
• Length: 257 a.a.
• NCBI ID: WP_000055337.1
• Uniprot ID: P63843
• Organism: Staphylococcus aureus strain THI2018-120
• Function: repression of comK (predicted from homology) Competence regulation

Genomic Context

Location: 1256707..1267480

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ST1232TP_RS06090 (THI2018120TP_11700)	trmFO	1257051..1258358 (+)	1308	WP_221046811.1	FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO	-
ST1232TP_RS06095 (THI2018120TP_11710)	xerC	1258775..1259671 (+)	897	WP_001015606.1	tyrosine recombinase XerC	-
ST1232TP_RS06100 (THI2018120TP_11720)	hslV	1259668..1260213 (+)	546	WP_000072681.1	ATP-dependent protease subunit HslV	-
ST1232TP_RS06105 (THI2018120TP_11730)	hslU	1260279..1261682 (+)	1404	WP_000379054.1	ATP-dependent protease ATPase subunit HslU	-
ST1232TP_RS06110 (THI2018120TP_11740)	codY	1261707..1262480 (+)	774	WP_000055337.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
ST1232TP_RS06115	-	1262531..1262623 (+)	93	WP_001790530.1	hypothetical protein	-
ST1232TP_RS06120 (THI2018120TP_11750)	rpsB	1262822..1263589 (+)	768	WP_000268484.1	30S ribosomal protein S2	-
ST1232TP_RS06125	-	1263623..1263736 (+)	114	WP_001789890.1	hypothetical protein	-
ST1232TP_RS06130 (THI2018120TP_11760)	tsf	1263771..1264652 (+)	882	WP_000201387.1	translation elongation factor Ts	-
ST1232TP_RS06135 (THI2018120TP_11770)	pyrH	1264789..1265511 (+)	723	WP_000057330.1	UMP kinase	-
ST1232TP_RS06140 (THI2018120TP_11780)	frr	1265530..1266084 (+)	555	WP_001280006.1	ribosome recycling factor	-
ST1232TP_RS06145 (THI2018120TP_11790)	-	1266457..1267227 (+)	771	WP_000473705.1	isoprenyl transferase	-

Sequence

Protein

• Length: 257 a.a.
• Molecular weight: 28755.13 Da
• Isoelectric Point: 6.0680

>NTDB_id=72155 ST1232TP_RS06110 WP_000055337.1 1261707..1262480(+) (codY) [Staphylococcus aureus strain THI2018-120]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide

• Length: 774 bp

>NTDB_id=72155 ST1232TP_RS06110 WP_000055337.1 1261707..1262480(+) (codY) [Staphylococcus aureus strain THI2018-120]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGATCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTTTTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGAGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCGAT
TGAACATATCTTTGAAGAACTTGGCGGTACGGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTTATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAGTAG

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (2-178)

• CodY helix-turn-helix domain (HTH_CodY) (198-255)

3D structure

• AlphaFold DB: P63843

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Bacillus subtilis subsp. subtilis str. 168	64.202	100	0.642
codY	Lactococcus lactis subsp. lactis strain DGCC12653	42.802	100	0.428