Detailed information NTG0072149

Bioinformatically predicted

Overview

• Name: cclA/cilC
• Type: Machinery gene
• Locus tag: EL334_RS09220
• Genome accession: NZ_AP019192
• Coordinates: 1717570..1718229 (+)
• Length: 219 a.a.
• NCBI ID: WP_033705163.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain ASP0581
• Function: processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1712570..1723229

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL334_RS09195 (ASP0581_17340)	-	1712875..1713192 (-)	318	WP_001151646.1	PTS sugar transporter subunit IIB	-
EL334_RS09200 (ASP0581_17350)	-	1713207..1714103 (-)	897	WP_000825669.1	PEP phosphonomutase	-
EL334_RS09205 (ASP0581_17360)	-	1714106..1715368 (-)	1263	WP_000413336.1	PTS sugar transporter subunit IIC	-
EL334_RS09210 (ASP0581_17370)	-	1715648..1716826 (+)	1179	WP_000175876.1	ROK family transcriptional regulator	-
EL334_RS09215 (ASP0581_17380)	-	1717054..1717500 (-)	447	WP_000155412.1	GNAT family N-acetyltransferase	-
EL334_RS09220 (ASP0581_17390)	cclA/cilC	1717570..1718229 (+)	660	WP_033705163.1	prepilin peptidase	Machinery gene
EL334_RS09225 (ASP0581_17400)	trpA	1718201..1718977 (-)	777	WP_033705162.1	tryptophan synthase subunit alpha	-
EL334_RS09230 (ASP0581_17410)	trpB	1718970..1720193 (-)	1224	WP_000331292.1	tryptophan synthase subunit beta	-
EL334_RS09235 (ASP0581_17420)	-	1720171..1720770 (-)	600	WP_000169913.1	phosphoribosylanthranilate isomerase	-
EL334_RS09240 (ASP0581_17430)	trpC	1720757..1721524 (-)	768	WP_000076567.1	indole-3-glycerol phosphate synthase TrpC	-
EL334_RS09245 (ASP0581_17440)	trpD	1721521..1722525 (-)	1005	WP_033705160.1	anthranilate phosphoribosyltransferase	-
EL334_RS09250 (ASP0581_17450)	-	1722536..1723102 (-)	567	WP_000601927.1	aminodeoxychorismate/anthranilate synthase component II	-

Sequence

Protein

• Length: 219 a.a.
• Molecular weight: 24860.98 Da
• Isoelectric Point: 7.5881

>NTDB_id=72149 EL334_RS09220 WP_033705163.1 1717570..1718229(+) (cclA/cilC) [Streptococcus pneumoniae strain ASP0581]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLG
LLFLLYSWELLSLGQVVLITAGLTLSIYDFRHQEYPLLVWMTFQLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide

• Length: 660 bp

>NTDB_id=72149 EL334_RS09220 WP_033705163.1 1717570..1718229(+) (cclA/cilC) [Streptococcus pneumoniae strain ASP0581]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCCCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAGGTCCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGAGCAT
CTATGACTTTCGCCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCAGCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGTGCAGGGGATTTCCTT
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTTTGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (8-89)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cclA/cilC	Streptococcus pneumoniae TIGR4	97.717	100	0.977
cclA/cilC	Streptococcus pneumoniae Rx1	96.347	100	0.963
cclA/cilC	Streptococcus pneumoniae D39	96.347	100	0.963
cclA/cilC	Streptococcus pneumoniae R6	96.347	100	0.963
cclA/cilC	Streptococcus mitis SK321	91.781	100	0.918
cclA/cilC	Streptococcus mitis NCTC 12261	86.758	100	0.868