Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD1   Type   Regulator
Locus tag   PUW52_RS02880 Genome accession   NZ_CP118078
Coordinates   550418..551059 (+) Length   213 a.a.
NCBI ID   WP_274984569.1    Uniprot ID   -
Organism   Streptococcus anginosus strain VSI16     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 545418..556059
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PUW52_RS02855 (PUW52_02855) holA 545806..546843 (+) 1038 WP_070241624.1 DNA polymerase III subunit delta -
  PUW52_RS02860 (PUW52_02860) - 546914..547519 (+) 606 WP_003040044.1 superoxide dismutase -
  PUW52_RS02865 (PUW52_02865) - 548132..548845 (+) 714 WP_024051975.1 type II CAAX endopeptidase family protein -
  PUW52_RS02870 (PUW52_02870) - 548986..549731 (+) 746 Protein_525 response regulator transcription factor -
  PUW52_RS02875 (PUW52_02875) - 550092..550412 (+) 321 WP_274984568.1 hypothetical protein -
  PUW52_RS02880 (PUW52_02880) comD/comD1 550418..551059 (+) 642 WP_274984569.1 GHKL domain-containing protein Regulator
  PUW52_RS02885 (PUW52_02885) - 551081..551230 (-) 150 WP_022526763.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  PUW52_RS02890 (PUW52_02890) - 551324..552685 (-) 1362 WP_024051971.1 bacteriocin secretion accessory protein -
  PUW52_RS02895 (PUW52_02895) comA/nlmT 552696..554849 (-) 2154 WP_142350988.1 peptide cleavage/export ABC transporter Regulator

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23910.05 Da        Isoelectric Point: 6.0722

>NTDB_id=720985 PUW52_RS02880 WP_274984569.1 550418..551059(+) (comD/comD1) [Streptococcus anginosus strain VSI16]
MKDYSHHIEGLYTEVRSFRHDYANILTTLKLGIEQNDIEIVKNVYDSVLKDSNKHFRNPKYDIGRLIHIKNDALKSLLAA
KCAQAQEHNVAVSLEIPEDIYSQGMELVDFITIVSVLCDNAIEAAAPNMTIAYVSSGQKQIFSVENSVKEESVDISQIFD
LGVSSKGATRGVGLHNVISILDRYPNVSLNTTSQNYCFRQTIEIQIKGNHYCN

Nucleotide


Download         Length: 642 bp        

>NTDB_id=720985 PUW52_RS02880 WP_274984569.1 550418..551059(+) (comD/comD1) [Streptococcus anginosus strain VSI16]
TTGAAAGACTACAGTCATCATATTGAGGGATTATATACAGAAGTTCGGAGTTTTCGGCATGATTACGCAAATATTTTAAC
GACTTTGAAATTAGGAATTGAGCAAAATGATATAGAAATTGTAAAAAATGTTTATGACTCAGTGTTAAAAGATTCCAATA
AGCACTTTCGTAATCCAAAGTATGATATTGGACGATTAATCCATATCAAAAATGATGCTTTAAAGAGCCTGTTAGCAGCT
AAGTGTGCACAAGCTCAAGAACATAATGTGGCAGTTTCATTGGAGATTCCAGAAGATATTTATTCACAGGGAATGGAATT
AGTTGACTTTATCACTATTGTCTCCGTTTTGTGCGATAATGCTATTGAAGCTGCTGCTCCAAATATGACGATTGCCTATG
TTTCATCAGGACAAAAGCAGATATTTTCCGTTGAAAATTCAGTAAAAGAAGAAAGTGTGGATATTTCACAAATCTTTGAC
TTGGGAGTTAGTTCGAAAGGGGCTACGAGAGGAGTGGGACTGCATAATGTAATATCTATTTTGGATAGATATCCTAATGT
TTCGCTTAATACAACTAGTCAAAATTATTGTTTTCGTCAGACAATTGAGATTCAAATAAAAGGAAATCATTACTGTAATT
AA

Domains

Predicted by InterProScan.

GHKL domain (HATPase_c_5)

(105-205)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD1 Streptococcus equinus JB1

47.087

96.714

0.455
  comD/comD3 Streptococcus equinus JB1

43.269

97.653

0.423
  comD/blpH Streptococcus mutans UA159

43.478

97.183

0.423
  comD/comD2 Streptococcus equinus JB1

41.346

97.653

0.404