Detailed information NTG0720686

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: PUW62_RS05775
• Genome accession: NZ_CP118046
• Coordinates: 1162836..1165064 (+)
• Length: 742 a.a.
• NCBI ID: WP_274996652.1
• Uniprot ID: -
• Organism: Streptococcus anginosus strain VSI52
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1157836..1170064

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PUW62_RS05750 (PUW62_05750)	rpmG	1158682..1158831 (+)	150	WP_003024746.1	50S ribosomal protein L33	-
PUW62_RS05755 (PUW62_05755)	secG	1158871..1159104 (+)	234	WP_003024744.1	preprotein translocase subunit SecG	-
PUW62_RS05760 (PUW62_05760)	rnr	1159196..1161535 (+)	2340	WP_024051603.1	ribonuclease R	-
PUW62_RS05765 (PUW62_05765)	smpB	1161498..1161965 (+)	468	WP_024051602.1	SsrA-binding protein SmpB	-
PUW62_RS05770 (PUW62_05770)	comEA/celA/cilE	1162148..1162852 (+)	705	WP_024051601.1	helix-hairpin-helix domain-containing protein	Machinery gene
PUW62_RS05775 (PUW62_05775)	comEC/celB	1162836..1165064 (+)	2229	WP_274996652.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
PUW62_RS05780 (PUW62_05780)	-	1165146..1165706 (+)	561	WP_224783657.1	DUF805 domain-containing protein	-
PUW62_RS05785 (PUW62_05785)	-	1166336..1167322 (+)	987	Protein_1102	Gfo/Idh/MocA family oxidoreductase	-
PUW62_RS05790 (PUW62_05790)	-	1167346..1167999 (+)	654	WP_024051596.1	uracil-DNA glycosylase	-
PUW62_RS05795 (PUW62_05795)	mutX	1168036..1168506 (+)	471	WP_024051595.1	8-oxo-dGTP diphosphatase	Machinery gene
PUW62_RS05800 (PUW62_05800)	-	1168519..1169796 (+)	1278	WP_024051594.1	dihydroorotase	-

Sequence

Protein

• Length: 742 a.a.
• Molecular weight: 85040.90 Da
• Isoelectric Point: 9.9870

>NTDB_id=720686 PUW62_RS05775 WP_274996652.1 1162836..1165064(+) (comEC/celB) [Streptococcus anginosus strain VSI52]
MSQWIKKFPIKPIYIAFLLVWLYFAIYPSSWLGWLGFIFLVIRLFRFYSPKECFMTFMILSCFASFFFIRREIAEQQTKA
EPSPIKQVAVLPDTIKVNGDSLSFRGKANRQTYQVYHKLKSKEEQLAFQNLSSLVALTVEGDFEIPEKKRNFAGFDYQSY
LKTQGIYRILKVDTILSSQDKISLHPLEWLSSWRRKALVFIKNHFPNPMSNYMTGLLFGALDTDFDEMSNLYSSLGIIHL
FALSGMQVGFFMEGFRKLLLRLGFTQEMVRKCQYPFSFFYAGMTGFSVSVVRSLVQKLLSQHGITKLDNFALTMMILSLI
MPSFLLSAGGVLSCVYAFVISVIDFEGLASWRKVVVESSVISLGILPILIFYFGEFQPWSILLTFVFSLIFDAMMLPGLT
LIFLFSPLIKLTQVNFLFEGLENSIRWIASVFGKPIVFGQPSPLLLIVMLLVLAILYDVRKNKKWVIFLSLFLSLLFFIN
KFPLQNEITMVDVGQGDSIFLRDWKGKNVLIDVGGREEIRTKEAWQKRAISSNAEKTLIPYLKSRGVDTIDTLVLTNPNP
DYAGDVLGVAKKFAIKKIYISRSSLSNADFLEKLRKLNTFIHVVKQGDKLPIFDHHLQVLSGVSKNDHSIVLYGQFFRTR
FLFASDLKEEGEAKLMQHYPKLKTDVLKVGQHEAKDSSSSKFLQQIEPTVALISVEKNNQSKQPSQDTIERFAQLPAKVY
RTDEQGAVKFSGWTNWRLEMVK

Nucleotide

• Length: 2229 bp

>NTDB_id=720686 PUW62_RS05775 WP_274996652.1 1162836..1165064(+) (comEC/celB) [Streptococcus anginosus strain VSI52]
ATGTCACAGTGGATTAAAAAATTTCCGATTAAGCCGATTTACATTGCTTTCTTACTTGTCTGGTTATATTTTGCAATCTA
TCCAAGTAGCTGGTTAGGCTGGTTGGGTTTTATCTTTCTGGTAATTCGTCTTTTTCGCTTTTATTCACCGAAAGAATGTT
TCATGACCTTCATGATCCTCTCTTGTTTTGCTAGTTTTTTCTTTATTCGTAGGGAAATAGCAGAGCAGCAAACAAAAGCA
GAACCTTCTCCCATAAAACAAGTGGCAGTTCTACCTGACACGATTAAGGTAAATGGAGATTCGCTTTCTTTTCGTGGTAA
AGCTAATAGGCAGACTTATCAAGTTTACCACAAATTGAAATCAAAGGAAGAGCAGTTGGCTTTTCAAAATCTCTCTAGTT
TGGTTGCGTTGACCGTTGAAGGAGATTTTGAAATTCCTGAGAAGAAGCGTAATTTTGCTGGTTTTGATTACCAATCTTAT
TTAAAAACGCAAGGGATTTATCGAATTTTAAAAGTAGATACCATTTTATCGAGCCAAGATAAAATCAGCTTGCACCCTTT
GGAGTGGCTCTCTAGCTGGCGAAGAAAGGCACTGGTATTTATCAAGAACCATTTTCCAAATCCGATGAGTAATTATATGA
CGGGGCTCTTATTTGGCGCCTTGGATACAGACTTTGACGAAATGAGCAATCTTTATTCTAGCTTGGGAATTATTCATTTA
TTTGCGCTGTCTGGCATGCAAGTTGGCTTTTTTATGGAGGGATTTCGCAAGTTACTGTTAAGGCTGGGGTTCACACAAGA
AATGGTTCGTAAATGCCAATATCCATTTTCTTTCTTTTATGCGGGAATGACTGGATTTTCAGTATCCGTTGTACGGAGCT
TAGTTCAGAAATTATTATCGCAACATGGTATCACTAAGTTAGATAATTTTGCTTTAACGATGATGATATTGTCCTTGATT
ATGCCGTCCTTTCTTTTGTCGGCAGGAGGAGTTCTCTCCTGTGTCTATGCTTTTGTCATTAGTGTGATAGATTTTGAAGG
TCTGGCTTCTTGGCGAAAAGTTGTTGTAGAGAGTAGCGTTATTTCACTTGGTATTTTACCGATTCTAATCTTTTACTTTG
GCGAATTTCAACCTTGGTCTATTTTGTTGACATTTGTTTTTTCACTGATTTTTGATGCAATGATGTTGCCAGGCTTGACG
TTAATTTTTCTTTTTTCGCCTTTGATAAAGTTGACTCAAGTCAATTTTCTATTTGAAGGTTTAGAAAATAGTATTCGTTG
GATAGCAAGTGTCTTTGGTAAACCAATCGTTTTTGGGCAGCCCAGTCCGCTTTTGCTGATTGTTATGCTGCTTGTACTGG
CTATTTTGTATGATGTTAGAAAAAATAAAAAATGGGTAATATTTCTTAGTCTGTTTCTTTCATTACTCTTTTTCATAAAT
AAATTTCCTTTGCAAAACGAGATCACAATGGTGGATGTCGGGCAAGGAGATAGTATTTTTCTGAGAGACTGGAAAGGAAA
AAATGTATTGATTGATGTTGGCGGACGTGAGGAAATTAGAACAAAAGAAGCTTGGCAAAAACGAGCAATTAGCTCAAATG
CAGAAAAAACTTTGATTCCTTATCTAAAAAGTCGTGGTGTAGATACGATTGATACTTTAGTCTTAACAAATCCTAATCCA
GATTATGCAGGAGATGTATTAGGAGTTGCTAAAAAGTTTGCAATAAAAAAAATTTATATTTCCAGAAGTAGTCTAAGCAA
TGCAGATTTTCTAGAGAAATTAAGGAAACTAAACACATTCATTCATGTTGTAAAACAAGGCGACAAACTTCCTATTTTTG
ATCATCATTTGCAAGTTCTTTCGGGTGTTAGCAAGAACGACCATTCGATCGTTTTATATGGTCAGTTTTTCCGTACAAGA
TTTTTATTTGCAAGCGACTTGAAAGAAGAGGGCGAAGCAAAGTTAATGCAGCATTATCCAAAGTTGAAAACAGATGTTTT
GAAAGTCGGACAGCATGAAGCCAAGGACTCATCAAGTTCAAAATTTTTGCAACAAATAGAACCAACGGTTGCGCTCATTT
CTGTTGAGAAAAATAATCAATCTAAGCAACCTAGTCAAGATACAATAGAGCGATTTGCACAATTGCCTGCTAAAGTCTAT
CGGACAGATGAACAAGGGGCAGTTAAATTTTCAGGGTGGACAAACTGGCGATTAGAGATGGTCAAGTAA

Domains

Predicted by InterProScan.

• Competence protein (Competence) (216-460)

• Domain of unknown function (DUF4131) (DUF4131) (28-175)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-592)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	54.618	100	0.55
comEC/celB	Streptococcus mitis NCTC 12261	53.887	100	0.542
comEC/celB	Streptococcus pneumoniae TIGR4	53.548	100	0.539
comEC/celB	Streptococcus pneumoniae Rx1	52.744	100	0.531
comEC/celB	Streptococcus pneumoniae D39	52.744	100	0.531
comEC/celB	Streptococcus pneumoniae R6	52.744	100	0.531
comEC	Lactococcus lactis subsp. cremoris KW2	47.651	100	0.478