Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   PUW62_RS04560 Genome accession   NZ_CP118046
Coordinates   924922..926910 (+) Length   662 a.a.
NCBI ID   WP_024052272.1    Uniprot ID   A0A412PMG2
Organism   Streptococcus anginosus strain VSI52     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 919922..931910
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PUW62_RS04545 (PUW62_04545) - 920786..921526 (-) 741 WP_070241651.1 amino acid ABC transporter ATP-binding protein -
  PUW62_RS04550 (PUW62_04550) - 921526..923709 (-) 2184 WP_070241650.1 ABC transporter substrate-binding protein/permease -
  PUW62_RS04555 (PUW62_04555) - 923872..924831 (+) 960 WP_070241649.1 CPBP family intramembrane glutamic endopeptidase -
  PUW62_RS04560 (PUW62_04560) uvrB 924922..926910 (+) 1989 WP_024052272.1 excinuclease ABC subunit UvrB Machinery gene
  PUW62_RS04565 (PUW62_04565) - 926941..927486 (+) 546 WP_070241648.1 DUF1697 domain-containing protein -
  PUW62_RS04570 (PUW62_04570) pptA 927616..928359 (+) 744 WP_070241647.1 ABC transporter ATP-binding protein Regulator
  PUW62_RS04575 (PUW62_04575) - 928349..929989 (+) 1641 WP_070241646.1 hypothetical protein -
  PUW62_RS04580 (PUW62_04580) hemW 930115..931245 (+) 1131 WP_024052268.1 radical SAM family heme chaperone HemW -

Sequence

Protein


Download         Length: 662 a.a.        Molecular weight: 75735.65 Da        Isoelectric Point: 4.4831

>NTDB_id=720676 PUW62_RS04560 WP_024052272.1 924922..926910(+) (uvrB) [Streptococcus anginosus strain VSI52]
MINRITDNKFKLVSKYEPSGDQPQAIEQLVDNIEGGEKAQILMGATGTGKTYTMSQVIQKVNKPTLVIAHNKTLAGQLYG
EFKEFFPDNAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYS
DSVVSLRPGLEISRDQLLNDLVDIQFERNDIDFQRGKFRVRGDVVEIFPASRDEHAFRVEFFGDEIDRIREVEVLTGQVL
GEVDHLAIFPATHFMTNDENMEIAIGKIQAELEDQLGFFEREGKLLEAQRLKQRTDYDIEMLREMGYTNGVENYSRHMDG
RSEGEPPYTLLDFFPDDFLIMVDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVHQIVYVSAT
PGDYEREQTDTVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINVRTEKNERTFITTLTKKMAEDLTDYFKEMGVKVKYM
HSDIKTLERTEIIRDLRLGVFDVLVGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADT
ITDSMQKAMDETARRRQIQMAYNEEHGIVPQTIQKEIRDLISVTKSALPDKEEVVDIESLNKQERKDMIKKLEGQMQEAA
GLLDFELAAQIRDMILEIKAVD

Nucleotide


Download         Length: 1989 bp        

>NTDB_id=720676 PUW62_RS04560 WP_024052272.1 924922..926910(+) (uvrB) [Streptococcus anginosus strain VSI52]
ATGATAAATAGAATTACGGACAATAAATTTAAATTAGTTTCCAAGTATGAGCCTTCAGGAGATCAACCACAGGCGATTGA
GCAATTAGTGGATAATATAGAGGGTGGTGAGAAAGCTCAGATTCTCATGGGAGCGACAGGAACTGGGAAGACCTACACTA
TGAGTCAGGTCATCCAAAAGGTCAATAAACCGACCCTAGTTATCGCTCATAATAAAACCCTGGCTGGTCAGCTCTATGGT
GAGTTTAAGGAGTTTTTTCCTGACAATGCGGTTGAATACTTCGTGTCTTACTATGACTATTACCAACCGGAAGCCTATGT
GCCTTCTAGTGATACCTATATTGAGAAGGACAGCTCGGTCAATGATGAGATTGACAAACTTCGTCACTCAGCAACCTCGG
CTCTCTTGGAGCGCAACGATGTGATTGTTGTGGCATCAGTCAGCTGCATTTATGGTTTGGGCTCGCCTAAGGAATACTCC
GATAGCGTGGTCAGTCTGCGACCTGGTTTAGAGATTTCACGGGATCAACTTCTCAATGATTTGGTTGATATTCAATTTGA
GCGCAATGATATTGACTTTCAGCGGGGAAAATTTCGTGTGCGTGGCGATGTTGTGGAAATCTTCCCAGCTTCTCGCGATG
AACATGCCTTTCGGGTGGAATTTTTCGGTGATGAAATTGACCGCATTCGAGAAGTGGAAGTATTGACAGGTCAAGTGTTG
GGCGAAGTAGACCATTTAGCTATTTTTCCTGCCACTCACTTTATGACCAATGACGAAAATATGGAGATTGCTATTGGCAA
GATTCAAGCGGAATTAGAAGATCAGCTAGGCTTTTTTGAAAGAGAAGGGAAGCTTTTAGAAGCTCAGCGGTTGAAGCAAA
GAACGGACTATGATATTGAAATGCTGCGCGAAATGGGCTACACGAATGGTGTAGAGAATTATTCTCGCCACATGGACGGA
CGGAGTGAAGGTGAGCCACCTTACACTTTATTAGATTTCTTTCCTGATGATTTTTTAATCATGGTAGACGAAAGTCATAT
GACGATGGGGCAGATTAAAGGGATGTACAATGGTGACCGCTCGCGGAAGGAAATGCTGGTCAATTATGGTTTCCGCCTGC
CGTCTGCCTTGGACAATCGTCCGCTGCGTCGGGAAGAATTTGAAAGTCATGTGCACCAGATTGTTTACGTGTCTGCTACA
CCAGGGGATTATGAGCGAGAGCAGACGGATACAGTAATTGAGCAAATTATTCGACCAACTGGACTGCTGGATCCAGAAGT
TGAAGTGCGTCCGACTATGGGGCAAATAGATGATCTTTTAGGGGAAATCAACGTACGTACTGAAAAGAATGAGCGGACTT
TTATCACGACGTTGACTAAAAAGATGGCAGAAGATCTGACGGATTACTTTAAAGAAATGGGTGTCAAGGTCAAGTACATG
CACTCAGACATCAAGACTTTGGAGCGTACCGAGATTATCCGAGACCTGCGCTTGGGTGTTTTTGACGTTCTGGTTGGGAT
TAACCTGCTACGCGAGGGAATTGACGTTCCTGAAGTAAGCTTGGTTGCCATTCTCGATGCCGATAAGGAAGGTTTCCTAC
GTAACGAACGTGGCTTAATCCAGACCATTGGTCGCGCTGCCCGTAATAGTGAAGGCCACGTCATCATGTATGCTGACACG
ATCACAGATTCCATGCAAAAAGCTATGGATGAAACCGCCCGTCGTCGTCAGATTCAAATGGCTTATAATGAAGAACATGG
TATTGTACCGCAAACAATCCAGAAAGAAATCCGTGACCTAATCAGTGTGACAAAATCTGCTCTACCAGACAAGGAAGAAG
TGGTAGATATTGAAAGTCTTAACAAGCAGGAACGTAAAGATATGATTAAGAAACTAGAGGGACAAATGCAAGAAGCGGCT
GGTCTTTTGGATTTCGAACTTGCCGCTCAAATTCGCGATATGATTTTGGAGATTAAGGCGGTGGATTAG

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(626-660)

Helicase conserved C-terminal domain (Helicase_C)

(445-549)

Type III restriction enzyme, res subunit (ResIII)

(17-143)

Ultra-violet resistance protein B (UvrB)

(556-598)

UvrB interaction domain (UvrB_inter)

(164-254)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A412PMG2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

92.145

100

0.921
  uvrB Streptococcus pneumoniae D39

92.145

100

0.921
  uvrB Streptococcus pneumoniae TIGR4

91.994

100

0.92