Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   EL263_RS11075 Genome accession   NZ_AP018938
Coordinates   2064550..2065212 (-) Length   220 a.a.
NCBI ID   WP_000649968.1    Uniprot ID   A0A098Z9B1
Organism   Streptococcus pneumoniae strain ATCC 49619     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2059550..2070212
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL263_RS11050 (SPAT_2090) - 2059700..2059966 (-) 267 WP_001278167.1 Veg family protein -
  EL263_RS11055 (SPAT_2091) dnaB 2059968..2061320 (-) 1353 WP_000852486.1 replicative DNA helicase -
  EL263_RS11060 (SPAT_2092) rplI 2061364..2061816 (-) 453 WP_000864220.1 50S ribosomal protein L9 -
  EL263_RS11065 (SPAT_2093) - 2061813..2063786 (-) 1974 WP_000715124.1 DHH family phosphoesterase -
  EL263_RS11070 (SPAT_2094) hpf 2063922..2064470 (-) 549 WP_000599107.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  EL263_RS11075 (SPAT_2095) comFC/cflB 2064550..2065212 (-) 663 WP_000649968.1 ComF family protein Machinery gene
  EL263_RS11080 (SPAT_2096) comFA/cflA 2065209..2066507 (-) 1299 WP_114880798.1 DEAD/DEAH box helicase Machinery gene
  EL263_RS11085 (SPAT_2097) - 2066563..2067198 (+) 636 WP_000395739.1 YigZ family protein -
  EL263_RS11090 (SPAT_2098) cysK 2067483..2068409 (+) 927 WP_050105695.1 cysteine synthase A -
  EL263_RS11095 (SPAT_2099) tsf 2068530..2069570 (-) 1041 WP_000808063.1 translation elongation factor Ts -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25203.05 Da        Isoelectric Point: 7.7116

>NTDB_id=71986 EL263_RS11075 WP_000649968.1 2064550..2065212(-) (comFC/cflB) [Streptococcus pneumoniae strain ATCC 49619]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSTKCQDCQFWCKEGVGVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=71986 EL263_RS11075 WP_000649968.1 2064550..2065212(-) (comFC/cflB) [Streptococcus pneumoniae strain ATCC 49619]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAACAAAGTGTCAAGATTGTCAATTTTGGTGTAAAGAAGGAGTTGGAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAATAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A098Z9B1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae Rx1

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae D39

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae R6

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae TIGR4

99.091

100

0.991
  comFC/cflB Streptococcus mitis SK321

91.364

100

0.914
  comFC/cflB Streptococcus mitis NCTC 12261

90.909

100

0.909

Multiple sequence alignment