Detailed information NTG0071939

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: EL263_RS04845
• Genome accession: NZ_AP018938
• Coordinates: 904549..905502 (+)
• Length: 317 a.a.
• NCBI ID: WP_000495909.1
• Uniprot ID: A0A0H2UPP6
• Organism: Streptococcus pneumoniae strain ATCC 49619
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 899549..910502

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL263_RS04820	rpmG	900292..900441 (+)	150	WP_001809104.1	50S ribosomal protein L33	-
EL263_RS04825 (SPAT_0904)	secG	900481..900714 (+)	234	WP_000282517.1	preprotein translocase subunit SecG	-
EL263_RS04830 (SPAT_0905)	rnr	900816..903170 (+)	2355	WP_054387412.1	ribonuclease R	-
EL263_RS04835 (SPAT_0906)	smpB	903133..903600 (+)	468	WP_001051750.1	SsrA-binding protein SmpB	-
EL263_RS04840 (SPAT_0907)	tehB	903616..904476 (+)	861	WP_054387413.1	SAM-dependent methyltransferase TehB	-
EL263_RS04845 (SPAT_0908)	coiA	904549..905502 (+)	954	WP_000495909.1	competence protein CoiA	Machinery gene
EL263_RS04850 (SPAT_0909)	pepF	905521..907332 (+)	1812	WP_114880829.1	oligoendopeptidase F	Regulator
EL263_RS04855 (SPAT_0910)	-	907334..908047 (+)	714	WP_000230399.1	O-methyltransferase	-
EL263_RS04860 (SPAT_0911)	prsA	908114..909055 (+)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
EL263_RS04865 (SPAT_0912)	-	909172..909552 (-)	381	Protein_919	transposase	-
EL263_RS04875	-	909965..910060 (+)	96	Protein_920	IS630 family transposase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38243.86 Da
• Isoelectric Point: 8.9865

>NTDB_id=71939 EL263_RS04845 WP_000495909.1 904549..905502(+) (coiA) [Streptococcus pneumoniae strain ATCC 49619]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=71939 EL263_RS04845 WP_000495909.1 904549..905502(+) (coiA) [Streptococcus pneumoniae strain ATCC 49619]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTAAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGATATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: A0A0H2UPP6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	100	100	1
coiA	Streptococcus pneumoniae Rx1	99.369	100	0.994
coiA	Streptococcus pneumoniae D39	99.369	100	0.994
coiA	Streptococcus pneumoniae R6	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435