Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   EL271_RS11030 Genome accession   NZ_AP018937
Coordinates   2025147..2025809 (-) Length   220 a.a.
NCBI ID   WP_000649964.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain HU-OH     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2020147..2030809
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL271_RS11005 (SPOH_2044) - 2020297..2020563 (-) 267 WP_001278167.1 Veg family protein -
  EL271_RS11010 (SPOH_2045) dnaB 2020565..2021917 (-) 1353 WP_000852486.1 replicative DNA helicase -
  EL271_RS11015 (SPOH_2046) rplI 2021961..2022413 (-) 453 WP_000864220.1 50S ribosomal protein L9 -
  EL271_RS11020 (SPOH_2047) - 2022410..2024383 (-) 1974 WP_000715121.1 DHH family phosphoesterase -
  EL271_RS11025 (SPOH_2048) hpf 2024519..2025067 (-) 549 WP_000599107.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  EL271_RS11030 (SPOH_2049) comFC/cflB 2025147..2025809 (-) 663 WP_000649964.1 ComF family protein Machinery gene
  EL271_RS11035 (SPOH_2050) comFA/cflA 2025806..2027104 (-) 1299 WP_000867612.1 DEAD/DEAH box helicase Machinery gene
  EL271_RS11040 (SPOH_2051) - 2027160..2027795 (+) 636 WP_000395739.1 YigZ family protein -
  EL271_RS11045 (SPOH_2052) cysK 2028080..2029000 (+) 921 WP_000029867.1 cysteine synthase A -
  EL271_RS11055 (SPOH_2053) - 2029239..2029613 (-) 375 Protein_2029 IS66 family transposase -
  EL271_RS11060 - 2029586..2029873 (+) 288 Protein_2030 transposase -
  EL271_RS11065 (SPOH_2054) tnpB 2030028..2030351 (-) 324 WP_000973415.1 IS66 family insertion sequence element accessory protein TnpB -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25253.15 Da        Isoelectric Point: 7.3688

>NTDB_id=71911 EL271_RS11030 WP_000649964.1 2025147..2025809(-) (comFC/cflB) [Streptococcus pneumoniae strain HU-OH]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSIKCQDCQLWCKEGVEVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=71911 EL271_RS11030 WP_000649964.1 2025147..2025809(-) (comFC/cflB) [Streptococcus pneumoniae strain HU-OH]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAATAAAGTGTCAAGATTGTCAACTTTGGTGTAAAGAGGGAGTTGAAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAATAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae TIGR4

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae Rx1

99.091

100

0.991
  comFC/cflB Streptococcus pneumoniae D39

99.091

100

0.991
  comFC/cflB Streptococcus pneumoniae R6

99.091

100

0.991
  comFC/cflB Streptococcus mitis NCTC 12261

91.818

100

0.918
  comFC/cflB Streptococcus mitis SK321

90.909

100

0.909

Multiple sequence alignment