Detailed information NTG0718756

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: NWE21_RS05915
• Genome accession: NZ_CP102748
• Coordinates: 1181780..1182721 (-)
• Length: 313 a.a.
• NCBI ID: WP_012027201.1
• Uniprot ID: A0A2K1T0X9
• Organism: Streptococcus suis strain Transconjugant cSFJ45
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1176780..1187721

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NWE21_RS05890 (NWE21_05900)	prsA	1176885..1177886 (-)	1002	WP_002938100.1	peptidylprolyl isomerase PrsA	-
NWE21_RS05895 (NWE21_05905)	-	1177947..1178666 (-)	720	WP_009910106.1	O-methyltransferase	-
NWE21_RS05900 (NWE21_05910)	-	1178741..1179289 (-)	549	WP_002938103.1	DUF6630 family protein	-
NWE21_RS05905 (NWE21_05915)	-	1179305..1179745 (-)	441	WP_012775191.1	hypothetical protein	-
NWE21_RS05910 (NWE21_05920)	pepF	1179747..1181549 (-)	1803	WP_012027200.1	oligoendopeptidase F	Regulator
NWE21_RS05915 (NWE21_05925)	coiA	1181780..1182721 (-)	942	WP_012027201.1	competence protein CoiA	Machinery gene
NWE21_RS05920 (NWE21_05930)	metG	1182785..1184788 (-)	2004	WP_012775442.1	methionine--tRNA ligase	-
NWE21_RS05925 (NWE21_05935)	-	1184944..1185537 (+)	594	WP_012027204.1	DUF1361 domain-containing protein	-
NWE21_RS05930 (NWE21_05940)	-	1185838..1186875 (+)	1038	WP_012027206.1	3-deoxy-7-phosphoheptulonate synthase	-

Sequence

Protein

• Length: 313 a.a.
• Molecular weight: 36261.73 Da
• Isoelectric Point: 7.4147

>NTDB_id=718756 NWE21_RS05915 WP_012027201.1 1181780..1182721(-) (coiA) [Streptococcus suis strain Transconjugant cSFJ45]
MLVALDEDGQVFNVLENPAPQGSFSCPGCGGLVRYKSGKVLRSHFAHVTLRDCHYFSENESAQHLSLKSCLYRWLVNAEQ
VELEKCLTSIGQVADLFVNNSLALEVQCSGLPISRLQLRTQAYSEAGYQVLWLLGKDLWLKERLTNLHKQFLSFSMNMGF
HLWELDDEKKELRLRYLIHEDLRGKVHCLTKVFPFGEGNLLDILRLPFAKQALSHLTCPLDRDLPRYIAQQLYYKSPNWL
ALQAESYSRGENLLTKTAEEWYPHIRLPRSAIGFAQIQKDLTLVYQDFDQYYGNIEDKQKQVLYPPIIYRKPM

Nucleotide

• Length: 942 bp

>NTDB_id=718756 NWE21_RS05915 WP_012027201.1 1181780..1182721(-) (coiA) [Streptococcus suis strain Transconjugant cSFJ45]
ATGTTAGTAGCACTTGATGAAGATGGGCAAGTTTTTAATGTCTTGGAAAATCCTGCGCCGCAAGGCAGTTTTTCCTGTCC
AGGTTGTGGAGGACTTGTCCGATACAAATCAGGAAAAGTTCTGCGTTCGCACTTTGCCCATGTAACCCTGCGGGACTGCC
ACTATTTTTCCGAGAATGAGTCCGCTCAGCACCTGTCCCTCAAGTCTTGTCTGTACAGGTGGTTAGTCAATGCCGAACAA
GTTGAACTTGAAAAATGCTTGACTAGTATAGGACAGGTCGCTGATTTATTTGTCAATAATAGTCTAGCTTTGGAAGTTCA
ATGTTCCGGTCTGCCCATTTCTCGTTTGCAGCTGAGGACGCAAGCCTATAGTGAGGCTGGTTATCAGGTTCTTTGGTTGC
TTGGCAAGGATTTGTGGCTCAAGGAACGACTGACCAATTTGCACAAGCAATTTCTCTCTTTTAGTATGAATATGGGGTTT
CACCTCTGGGAATTGGATGATGAGAAGAAGGAATTGCGTCTTCGTTACCTTATTCACGAAGACTTACGAGGTAAGGTCCA
CTGTCTGACAAAGGTTTTTCCATTTGGCGAGGGAAATTTATTGGACATCTTGCGTCTGCCATTTGCCAAGCAAGCTTTAT
CGCATCTTACTTGCCCGTTAGATAGGGATTTGCCTCGCTACATTGCTCAACAGCTTTATTACAAATCCCCCAATTGGTTG
GCCCTGCAGGCAGAGTCTTATAGCCGAGGGGAGAATTTGCTGACAAAGACGGCAGAAGAATGGTACCCCCACATCCGTCT
GCCCCGCTCTGCCATTGGCTTTGCCCAAATACAAAAAGATTTAACCCTAGTTTATCAGGATTTTGACCAGTATTACGGCA
ATATTGAAGACAAGCAGAAACAGGTTCTATATCCACCTATAATTTATAGAAAACCAATGTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (21-230)

3D structure

• AlphaFold DB: A0A2K1T0X9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus mitis NCTC 12261	53.205	99.681	0.53
coiA	Streptococcus pneumoniae TIGR4	51.603	99.681	0.514
coiA	Streptococcus pneumoniae Rx1	51.603	99.681	0.514
coiA	Streptococcus pneumoniae D39	51.603	99.681	0.514
coiA	Streptococcus pneumoniae R6	51.603	99.681	0.514
coiA	Lactococcus lactis subsp. cremoris KW2	42.5	100	0.435