Detailed information NTG0718748

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: NWE21_RS03670
• Genome accession: NZ_CP102748
• Coordinates: 720204..722441 (+)
• Length: 745 a.a.
• NCBI ID: WP_012775040.1
• Uniprot ID: -
• Organism: Streptococcus suis strain Transconjugant cSFJ45
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 715204..727441

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NWE21_RS03645 (NWE21_03655)	-	715275..716204 (-)	930	WP_012775038.1	ABC transporter substrate-binding protein	-
NWE21_RS03650 (NWE21_03660)	-	716217..717002 (-)	786	WP_011922762.1	ABC transporter ATP-binding protein	-
NWE21_RS03655 (NWE21_03665)	-	717154..718599 (-)	1446	WP_011922188.1	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	-
NWE21_RS03660 (NWE21_03670)	-	718746..719495 (+)	750	WP_012775039.1	lysophospholipid acyltransferase family protein	-
NWE21_RS03665 (NWE21_03675)	-	719558..720220 (+)	663	WP_011922190.1	helix-hairpin-helix domain-containing protein	-
NWE21_RS03670 (NWE21_03680)	comEC/celB	720204..722441 (+)	2238	WP_012775040.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
NWE21_RS03675 (NWE21_03685)	-	722458..722583 (+)	126	Protein_680	IS982 family transposase	-
NWE21_RS03680 (NWE21_03690)	-	722766..723422 (+)	657	WP_011922763.1	CBS domain-containing protein	-
NWE21_RS03685 (NWE21_03695)	-	723516..724343 (+)	828	WP_011922194.1	hypothetical protein	-
NWE21_RS03690 (NWE21_03700)	-	724349..725620 (+)	1272	WP_011922195.1	toxic anion resistance protein	-
NWE21_RS03695 (NWE21_03705)	-	725657..726523 (-)	867	WP_002935357.1	YitT family protein	-
NWE21_RS03700 (NWE21_03710)	tmk	726698..727336 (+)	639	WP_012775041.1	dTMP kinase	-

Sequence

Protein

• Length: 745 a.a.
• Molecular weight: 83965.92 Da
• Isoelectric Point: 7.8195

>NTDB_id=718748 NWE21_RS03670 WP_012775040.1 720204..722441(+) (comEC/celB) [Streptococcus suis strain Transconjugant cSFJ45]
MSRLSKLPCQPVHLAVLAVAAYFAVHSFSLLTMCLLSLVLAVFGVRQGKTVFLKTLPLLTLCGLFFGCQKVQWERAAQSA
PEQVTTVQVIPDTIDINGDSLSFRGRADGQNYQVFYKLTSQEEQTYFQNLADLVQLEVEAEVSLPAGQRNFKGFDYQAYL
KTQGIYRTVKLTAIKKIVPVQSWNVFDWLSTWRRQALVYVKTNFPAPMSHYMTGLLFGELDSDFDQMSDLYSSLGIIHLF
ALSGMQVGFFIDKFRWILLRLGLTKETVDKLQIPFSLVYAGLTGFSVSVVRSLVQKILGNLGLRKLDNFAVTVFICLLIL
PRFLLTAGGVLTFTYAFLLTVFDFEDLGQVKKAAVESLSISLGILPVLMTYFYAFQPLSILLTFVFSFVFDVLLLPGLSV
IFLLSPVVKMTWVNGFFVFMEKIIVWVADLGLRPWILGKPSELVLLLLLVSLFLLYDFHRRKKWLLGLSLVLALLFFITK
HPLENEVTVLDIGQGDSIFLRDMRGRTVLIDVGGRVDFAAKEAWQERSRQANAERTLIPYLHSRGVDRIDSLVLTHTDTD
HVGDVLEVAKQVQIGRIVVSPGSLTVPDFVATLKKINVPVHVVKVGDRLPIFDSYLEVLYPDGTGDGGNNDSIVLYGRLL
ETNFLFTGDLEQGELDLIETYPNLPVDVLKAGHHGSKGSSYPEFLDHIGAKIALVSAGENNRYKHPHQETLERFDSRNIQ
VYRTDQQGAIRFRGWKEWKIETVRR

Nucleotide

• Length: 2238 bp

>NTDB_id=718748 NWE21_RS03670 WP_012775040.1 720204..722441(+) (comEC/celB) [Streptococcus suis strain Transconjugant cSFJ45]
ATGTCACGGTTGAGTAAGCTCCCCTGCCAGCCCGTTCACCTGGCAGTCTTGGCGGTGGCAGCTTACTTTGCAGTCCACTC
TTTTTCCCTCTTGACAATGTGCCTGCTCAGCTTGGTGTTAGCTGTCTTTGGTGTTCGGCAAGGTAAGACAGTTTTCCTCA
AAACGCTGCCGCTTCTAACCCTGTGTGGTCTCTTTTTCGGATGCCAAAAGGTCCAATGGGAGCGGGCAGCTCAGTCAGCC
CCAGAGCAAGTGACGACTGTGCAGGTCATTCCAGATACCATAGACATCAATGGCGACAGCTTGTCTTTTCGTGGTCGGGC
TGATGGACAAAACTATCAGGTTTTCTACAAATTAACCAGTCAGGAGGAGCAGACCTATTTTCAAAATCTGGCAGACCTGG
TCCAGCTAGAAGTGGAAGCAGAGGTCAGCCTGCCAGCTGGTCAGCGGAATTTCAAGGGCTTTGACTATCAGGCCTATCTG
AAAACACAGGGCATCTATCGGACTGTCAAGCTAACGGCGATTAAGAAGATTGTCCCTGTCCAGTCTTGGAATGTTTTTGA
CTGGCTGTCAACTTGGCGGAGGCAGGCCTTGGTCTATGTCAAAACCAATTTTCCGGCTCCCATGAGTCACTACATGACAG
GGCTTTTGTTTGGGGAGCTGGATAGTGATTTTGACCAGATGAGTGACCTCTATTCCAGTCTAGGAATCATTCATCTCTTT
GCCCTGTCTGGTATGCAGGTGGGCTTTTTCATCGACAAGTTTCGTTGGATTTTGTTGCGTCTGGGCTTGACCAAGGAAAC
AGTGGATAAGTTACAAATTCCCTTTTCCCTTGTCTATGCTGGTTTGACAGGCTTTTCTGTGTCGGTGGTGCGGTCCTTGG
TCCAAAAAATTCTGGGTAATCTAGGCTTGCGGAAGTTGGATAATTTTGCGGTGACGGTCTTTATCTGTCTGTTGATACTG
CCCCGATTTTTACTGACAGCAGGAGGAGTGCTGACTTTTACTTATGCTTTCTTGCTGACGGTCTTTGATTTTGAGGATTT
GGGGCAGGTCAAAAAGGCTGCGGTGGAGAGCCTCAGTATTTCACTGGGAATTTTGCCGGTGCTTATGACCTATTTCTATG
CCTTTCAGCCTCTATCTATCCTCTTGACCTTTGTCTTTTCCTTTGTCTTTGATGTCCTACTCTTGCCAGGTTTGTCAGTC
ATTTTTCTCCTGTCGCCAGTTGTCAAGATGACTTGGGTCAACGGATTTTTCGTCTTTATGGAGAAAATCATTGTCTGGGT
GGCTGATTTGGGATTGCGGCCTTGGATACTGGGCAAGCCGTCTGAGCTGGTCCTCTTGCTTTTGCTGGTCAGCCTCTTCT
TGCTCTACGATTTCCACAGGAGAAAGAAATGGCTTCTAGGACTGAGCTTGGTCCTCGCTCTGCTATTTTTCATCACCAAA
CACCCGCTGGAAAATGAGGTGACGGTGCTGGACATCGGGCAGGGGGACAGCATCTTTTTGCGGGATATGCGGGGGCGGAC
GGTTCTGATTGATGTAGGCGGACGAGTCGATTTCGCGGCCAAGGAAGCGTGGCAGGAGCGGTCTCGGCAGGCAAATGCAG
AGCGGACTTTGATTCCCTATCTGCATAGTCGGGGTGTGGATAGGATTGATAGTTTAGTCCTGACCCACACCGACACAGAC
CATGTGGGGGATGTGCTGGAAGTGGCGAAGCAGGTCCAGATTGGTCGGATTGTCGTGTCGCCGGGAAGTCTGACGGTGCC
TGACTTTGTAGCGACCTTGAAAAAAATCAATGTTCCTGTCCATGTGGTAAAAGTGGGCGACCGCCTACCAATTTTTGACT
CCTATCTGGAGGTCCTCTATCCAGACGGGACAGGCGACGGTGGCAATAATGACTCCATTGTCCTTTACGGTCGCTTGTTG
GAAACTAACTTTCTCTTTACAGGAGACCTGGAGCAAGGGGAGTTGGACTTGATAGAAACCTATCCCAACCTGCCTGTCGA
TGTCCTCAAAGCCGGTCACCATGGCTCCAAAGGCTCTTCTTATCCTGAATTTTTAGACCATATCGGTGCCAAGATTGCCT
TGGTATCTGCTGGAGAAAACAACCGCTACAAGCATCCTCACCAAGAAACCTTGGAACGATTTGACAGCCGGAATATCCAA
GTCTATCGCACAGACCAGCAAGGAGCCATTCGCTTCCGAGGTTGGAAGGAGTGGAAGATTGAGACGGTGAGGAGGTAA

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (493-698)

• Domain of unknown function (DUF4131) (DUF4131) (30-175)

• Competence protein (Competence) (215-461)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	53.774	99.597	0.536
comEC/celB	Streptococcus mitis NCTC 12261	52.782	98.926	0.522
comEC/celB	Streptococcus pneumoniae TIGR4	51.973	98.658	0.513
comEC/celB	Streptococcus pneumoniae Rx1	51.701	98.658	0.51
comEC/celB	Streptococcus pneumoniae D39	51.701	98.658	0.51
comEC/celB	Streptococcus pneumoniae R6	51.701	98.658	0.51
comEC	Lactococcus lactis subsp. cremoris KW2	49.399	100	0.497