Detailed information NTG0718694

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: NWE22_RS03505
• Genome accession: NZ_CP102747
• Coordinates: 675266..677503 (+)
• Length: 745 a.a.
• NCBI ID: WP_277745607.1
• Uniprot ID: -
• Organism: Streptococcus parasuis strain SFJ45
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 670266..682503

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NWE22_RS03475 (NWE22_03475)	-	671534..671943 (+)	410	Protein_646	GNAT family N-acetyltransferase	-
NWE22_RS03480 (NWE22_03480)	-	672064..672675 (+)	612	WP_277745606.1	NAD(P)H-dependent oxidoreductase	-
NWE22_RS03485 (NWE22_03485)	-	672693..672965 (-)	273	WP_239604638.1	GIY-YIG nuclease family protein	-
NWE22_RS03490 (NWE22_03490)	-	672955..673704 (-)	750	WP_239604639.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
NWE22_RS03495 (NWE22_03495)	-	673796..674539 (+)	744	WP_239604640.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
NWE22_RS03500 (NWE22_03500)	-	674605..675282 (+)	678	WP_216807028.1	helix-hairpin-helix domain-containing protein	-
NWE22_RS03505 (NWE22_03505)	comEC/celB	675266..677503 (+)	2238	WP_277745607.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
NWE22_RS03510 (NWE22_03510)	holA	677567..678598 (+)	1032	WP_277745608.1	DNA polymerase III subunit delta	-
NWE22_RS03515 (NWE22_03515)	sodA	678675..679280 (+)	606	WP_024391732.1	superoxide dismutase SodA	-
NWE22_RS03520 (NWE22_03520)	rplS	679482..679829 (+)	348	WP_011921928.1	50S ribosomal protein L19	-
NWE22_RS03525 (NWE22_03525)	-	680101..681840 (+)	1740	WP_171988549.1	ABC transporter transmembrane domain-containing protein	-

Sequence

Protein

• Length: 745 a.a.
• Molecular weight: 84079.17 Da
• Isoelectric Point: 6.7478

>NTDB_id=718694 NWE22_RS03505 WP_277745607.1 675266..677503(+) (comEC/celB) [Streptococcus parasuis strain SFJ45]
MSRLIRLPCQPIHFAVLAVLAYFAVHSFSLLTMSLLSLLLAVFGLRQGKVVFIKTLPLLALCGLFFECQKIQWERTNLWA
PEQVTTVQVIPDTIDVNGDSLSFRGRAEGQVFQVFYKLASQEEQTYFQELTDLVQLEVDAEVSQPAGQRNFNGFDYQAYL
NTQGIYRTVKISTINNILPIHSWNIFDWLSTWRRQALVYIKSHFPAPMSHYMTGLLLGELDSDFDQMSDLYSSLGIIHLF
ALSGMQVGFFIDKFRWLLLRLGLTKETVDKLQIPFSLVYAGLTGFSVSVVRSLVQKILGNLGLRKLDNFAATVFVCLLLM
PRFLLTAGGVLTFTYALLLTVFDFEELRQLKKVAVESLSISLGILPVLMSYFFAFQPLSILLTFVFSFVFDVLLLPGLSV
ILLLSPFIKITWVNGFFILMEKIIVWVAELGISPWILGKPTGLVFLLLLVCLFLLYDFHREKKCLLGLSLMLALLFFITK
HPLENEVTVVDVGQGDSIFLRDMRGRTVLIDVGGRVDFAAKEAWRERSREANAERTLIPYLHSRGVDRIDSLVLTHTDAD
HAGDVLEVAKQIQIGKIYVSPGSLTVPDFVATLRKINVPVHVVNPGDRLPIFDSYLEVLYPNGIGDGGNNDSIVLYGRLL
KTNFLFTGDLEQGELDLITSYPQLPVDVLKAGHHGSKGSSYPEFLDHIGAKIALISAGENNRYQHPHKETLERLDSQNMQ
VYRTDLQGAIRFRGWKQWSIETVKE

Nucleotide

• Length: 2238 bp

>NTDB_id=718694 NWE22_RS03505 WP_277745607.1 675266..677503(+) (comEC/celB) [Streptococcus parasuis strain SFJ45]
ATGTCACGGTTGATTAGACTCCCCTGTCAGCCCATTCACTTTGCAGTTTTGGCGGTGTTAGCCTACTTTGCAGTTCACTC
TTTTTCCCTTTTGACAATGAGCCTGCTGAGTCTGTTACTAGCAGTCTTTGGGCTTCGGCAAGGAAAGGTGGTCTTCATCA
AAACGCTACCGCTTCTAGCCTTATGTGGTCTCTTCTTCGAATGTCAGAAGATACAATGGGAGCGGACAAATCTATGGGCT
CCAGAGCAAGTGACAACTGTGCAGGTTATTCCTGATACCATTGATGTCAACGGAGACAGTCTTTCTTTTCGTGGTCGGGC
TGAAGGACAAGTTTTTCAGGTTTTCTATAAACTTGCAAGTCAGGAAGAACAAACCTATTTTCAGGAGCTTACGGACTTGG
TGCAGTTAGAGGTAGATGCAGAAGTTAGCCAACCAGCAGGTCAACGTAATTTCAATGGTTTTGATTATCAGGCTTATCTC
AATACCCAGGGCATCTATCGGACAGTAAAAATAAGTACCATTAACAATATTCTCCCTATTCATTCTTGGAATATCTTTGA
CTGGTTGTCAACCTGGCGGAGGCAGGCTCTCGTTTATATCAAATCTCATTTTCCTGCTCCAATGAGCCACTACATGACTG
GATTACTATTGGGAGAGTTAGATAGTGACTTTGACCAAATGAGTGACCTCTATTCTAGTTTAGGGATCATTCATCTTTTT
GCCCTGTCTGGGATGCAGGTTGGTTTTTTCATTGACAAATTTCGCTGGCTTTTATTGCGTTTGGGTTTAACAAAGGAAAC
TGTCGATAAGCTTCAAATTCCATTTTCTCTTGTTTATGCAGGATTGACAGGATTTTCAGTCTCAGTCGTGCGGTCCTTGG
TCCAGAAAATTCTGGGTAATCTTGGACTACGAAAATTGGATAATTTTGCAGCAACAGTCTTTGTTTGTCTCTTGCTTATG
CCACGGTTTCTTCTGACTGCAGGCGGTGTGCTAACATTTACCTATGCTTTGTTATTGACAGTCTTTGATTTTGAAGAGCT
AAGGCAACTTAAGAAGGTAGCAGTGGAGAGTCTGAGTATTTCTCTTGGAATTTTACCGGTCTTGATGTCCTATTTTTTTG
CCTTTCAGCCCTTATCTATCCTTTTAACGTTTGTTTTTTCCTTTGTTTTTGATGTGTTGTTGTTACCTGGGCTATCTGTC
ATTCTTTTACTATCGCCCTTCATTAAAATTACGTGGGTCAACGGATTCTTTATCCTTATGGAAAAGATTATTGTATGGGT
GGCAGAATTGGGGATTAGCCCTTGGATTTTAGGAAAACCTACGGGCCTTGTCTTTTTGCTCTTGCTGGTCTGCCTTTTCT
TGCTTTATGATTTTCACAGAGAGAAGAAATGCCTCCTAGGACTGAGCCTGATGCTTGCTCTGCTATTTTTCATAACCAAA
CACCCGCTGGAAAACGAGGTGACGGTGGTAGACGTAGGGCAGGGGGATAGTATCTTTTTGCGGGACATGCGGGGGCGGAC
GGTTCTGATTGATGTGGGTGGTCGGGTTGACTTTGCTGCAAAGGAAGCTTGGCGGGAGCGGTCTAGGGAAGCAAATGCGG
AGCGAACTCTGATTCCTTACCTGCATAGTCGAGGTGTGGATAGGATTGATAGCTTAGTCTTGACCCATACCGATGCAGAT
CATGCGGGTGATGTGCTAGAAGTGGCTAAGCAGATTCAGATCGGTAAGATTTACGTTTCTCCAGGTAGTTTGACTGTACC
AGATTTTGTTGCGACTTTGAGGAAAATAAATGTCCCTGTTCATGTTGTAAATCCTGGAGATCGATTGCCCATTTTTGATT
CCTATCTAGAAGTTCTATATCCCAATGGAATCGGAGATGGTGGCAATAATGATTCGATTGTACTCTATGGTCGTTTGTTA
AAAACGAATTTCCTCTTTACCGGTGACTTGGAGCAAGGGGAATTAGATTTAATCACTTCTTATCCGCAGCTACCAGTCGA
TGTGCTGAAAGCAGGTCACCATGGTTCCAAGGGCTCTTCATATCCAGAATTTTTAGACCATATTGGAGCAAAAATTGCTC
TGATTTCTGCTGGTGAAAATAATCGCTATCAACATCCACACAAGGAAACTCTGGAACGTCTCGACAGTCAAAATATGCAG
GTTTACCGAACGGATCTGCAAGGAGCAATCCGTTTCCGAGGTTGGAAACAGTGGAGTATTGAAACGGTAAAAGAGTGA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (30-176)

• Competence protein (Competence) (215-458)

• Metallo-beta-lactamase superfamily (Lactamase_B) (491-698)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	53.146	100	0.533
comEC/celB	Streptococcus mitis NCTC 12261	52.589	98.523	0.518
comEC/celB	Streptococcus pneumoniae TIGR4	51.817	99.732	0.517
comEC/celB	Streptococcus pneumoniae Rx1	51.279	99.732	0.511
comEC/celB	Streptococcus pneumoniae D39	51.279	99.732	0.511
comEC/celB	Streptococcus pneumoniae R6	51.279	99.732	0.511
comEC	Lactococcus lactis subsp. cremoris KW2	47.797	100	0.481