Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   NWE23_RS03965 Genome accession   NZ_CP102746
Coordinates   814158..815384 (+) Length   408 a.a.
NCBI ID   WP_002934974.1    Uniprot ID   G7SE29
Organism   Streptococcus suis strain Transconjugant cAKJ47-2     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 809158..820384
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NWE23_RS03930 (NWE23_03940) - 810162..810497 (+) 336 WP_002934966.1 hypothetical protein -
  NWE23_RS03935 (NWE23_03945) - 810593..811552 (+) 960 WP_012775086.1 ROK family glucokinase -
  NWE23_RS03940 (NWE23_03950) - 811678..811956 (+) 279 WP_012775087.1 hypothetical protein -
  NWE23_RS03945 (NWE23_03955) - 811968..812270 (+) 303 WP_012775088.1 hypothetical protein -
  NWE23_RS03950 (NWE23_03960) - 812323..813162 (+) 840 WP_011922359.1 thymidylate synthase -
  NWE23_RS03955 (NWE23_03965) - 813448..813960 (+) 513 WP_011922360.1 dihydrofolate reductase -
  NWE23_RS03960 (NWE23_03970) - 813963..814136 (+) 174 WP_002934972.1 hypothetical protein -
  NWE23_RS03965 (NWE23_03975) clpX 814158..815384 (+) 1227 WP_002934974.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  NWE23_RS03970 (NWE23_03980) yihA 815440..816027 (+) 588 WP_012775089.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  NWE23_RS03975 (NWE23_03985) ndk 816050..816463 (+) 414 WP_012028095.1 nucleoside-diphosphate kinase -
  NWE23_RS03980 (NWE23_03990) - 816567..817238 (+) 672 WP_011922364.1 HIRAN domain-containing protein -
  NWE23_RS03985 (NWE23_03995) lepA 817520..819352 (+) 1833 WP_002943192.1 translation elongation factor 4 -
  NWE23_RS03990 (NWE23_04000) - 819402..819584 (-) 183 WP_002934978.1 4-oxalocrotonate tautomerase -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45318.84 Da        Isoelectric Point: 4.6382

>NTDB_id=718643 NWE23_RS03965 WP_002934974.1 814158..815384(+) (clpX) [Streptococcus suis strain Transconjugant cAKJ47-2]
MAVKHTHELIYCSFCGKNQEEVKKIIAGNNVFICNECVELAQEIIREELAEEVLTDLADTPKPQELLNILNNYVIGQDRA
KRALAVAVYNHYKRINFQDSRDENDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENIL
LKLLQAADFNIDRAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIHVDTKN
ILFIVGGAFDGIEEIVKQRLGEKIIGFGHNNRAIDEKESYMQHIIADDIQKFGIIPELIGRLPVFAALDQLTTEDLVRIL
TEPKNALVKQYQTLLSYDDVELDFDEDALLAIAEKAIERKTGARGLRSIIEETMLDVMFEVPGQDNVKRVRVTKAAVDGK
EKPLLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=718643 NWE23_RS03965 WP_002934974.1 814158..815384(+) (clpX) [Streptococcus suis strain Transconjugant cAKJ47-2]
ATGGCTGTTAAGCATACACATGAGCTAATCTATTGCTCATTTTGCGGAAAAAATCAAGAAGAAGTTAAAAAAATTATCGC
AGGGAACAATGTCTTCATTTGTAATGAGTGCGTGGAACTAGCACAGGAAATCATTCGTGAGGAACTGGCAGAAGAAGTTT
TGACAGACTTGGCCGATACGCCAAAGCCACAAGAATTACTCAATATCCTGAACAACTACGTCATCGGACAGGATCGTGCA
AAACGTGCTTTAGCAGTAGCCGTTTACAACCACTACAAACGTATCAATTTCCAAGATAGCCGTGATGAGAACGATGTTGA
TTTGCAAAAATCAAATATCCTCATGATTGGCCCGACTGGTTCAGGAAAAACCTTCCTAGCTCAGACCTTGGCTAAAAGTT
TGAATGTCCCGTTTGCTATTGCTGATGCGACCGCTCTTACTGAGGCAGGTTATGTTGGTGAAGACGTAGAAAATATCCTC
CTCAAACTTTTGCAGGCTGCAGACTTTAACATCGACCGTGCAGAAAGAGGAATTATCTATGTAGATGAAATTGATAAGAT
TGCCAAAAAAGGTGAAAATGTGTCCATTACCCGCGATGTATCTGGTGAAGGTGTCCAGCAAGCTCTCCTAAAAATTATCG
AGGGAACTGTGGCCAGCGTACCACCACAAGGCGGACGTAAACATCCAAACCAAGAAATGATTCACGTGGACACCAAAAAT
ATCCTGTTTATCGTTGGCGGTGCATTTGATGGTATCGAAGAAATCGTCAAACAGCGTCTCGGTGAAAAAATCATCGGTTT
TGGTCATAATAATCGTGCTATTGATGAAAAAGAATCATACATGCAACATATCATTGCAGACGATATTCAAAAATTCGGTA
TCATTCCAGAGTTGATTGGTCGCTTGCCTGTATTCGCAGCTTTGGACCAATTGACAACAGAGGATTTGGTACGCATTTTG
ACGGAACCGAAGAATGCTCTTGTAAAACAATACCAGACACTCTTGTCTTATGATGACGTGGAGCTTGACTTTGATGAGGA
CGCCTTGTTAGCAATTGCAGAAAAAGCAATTGAACGTAAAACTGGTGCTCGTGGACTTCGCTCTATCATTGAAGAAACGA
TGTTGGATGTCATGTTTGAGGTGCCAGGTCAAGATAACGTTAAACGCGTTCGTGTAACAAAAGCAGCAGTAGACGGTAAA
GAAAAGCCTTTACTAGAAACTGCATAA

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G7SE29

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

83.13

100

0.833
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.209

98.529

0.574