Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   EL277_RS09175 Genome accession   NZ_AP018936
Coordinates   1741135..1741794 (+) Length   219 a.a.
NCBI ID   WP_000565018.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain NU83127     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1736135..1746794
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL277_RS09155 (SPNU_1733) - 1736772..1737668 (-) 897 WP_000825664.1 PEP phosphonomutase -
  EL277_RS09160 (SPNU_1734) - 1737671..1738933 (-) 1263 WP_000413345.1 PTS sugar transporter subunit IIC -
  EL277_RS09165 (SPNU_1735) - 1739213..1740391 (+) 1179 WP_000175879.1 ROK family transcriptional regulator -
  EL277_RS09170 (SPNU_1736) - 1740619..1741065 (-) 447 WP_000155410.1 GNAT family N-acetyltransferase -
  EL277_RS09175 (SPNU_1737) cclA/cilC 1741135..1741794 (+) 660 WP_000565018.1 prepilin peptidase Machinery gene
  EL277_RS09180 (SPNU_1738) - 1741846..1742997 (-) 1152 WP_000481763.1 XRE family transcriptional regulator -
  EL277_RS09185 (SPNU_1739) - 1743012..1743743 (-) 732 WP_000934017.1 hypothetical protein -
  EL277_RS09190 - 1743963..1744073 (+) 111 Protein_1731 prepilin peptidase -
  EL277_RS09195 (SPNU_1740) trpA 1744045..1744821 (-) 777 WP_001127022.1 tryptophan synthase subunit alpha -
  EL277_RS09200 (SPNU_1741) trpB 1744814..1746037 (-) 1224 WP_000331297.1 tryptophan synthase subunit beta -
  EL277_RS09205 (SPNU_1742) - 1746015..1746614 (-) 600 WP_000169916.1 phosphoribosylanthranilate isomerase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24793.86 Da        Isoelectric Point: 7.6418

>NTDB_id=71803 EL277_RS09175 WP_000565018.1 1741135..1741794(+) (cclA/cilC) [Streptococcus pneumoniae strain NU83127]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELVLG
LLFLLYSWELLSLGQVVLITAGLTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLAACGIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=71803 EL277_RS09175 WP_000565018.1 1741135..1741794(+) (cclA/cilC) [Streptococcus pneumoniae strain NU83127]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAAGTTCGCTATCCTGTCTGGTATGCCCTCTTTGAATTAGTCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGTAT
CTACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTTGCTCTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGCGCAGGGGATTTCCTC
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTTGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAGAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTGCTTGTGGGATTATTTTTG
GTAAGCTACTGCTTGTCTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus pneumoniae Rx1

96.804

100

0.968
  cclA/cilC Streptococcus pneumoniae D39

96.804

100

0.968
  cclA/cilC Streptococcus pneumoniae R6

96.804

100

0.968
  cclA/cilC Streptococcus pneumoniae TIGR4

96.347

100

0.963
  cclA/cilC Streptococcus mitis SK321

92.237

100

0.922
  cclA/cilC Streptococcus mitis NCTC 12261

86.758

100

0.868

Multiple sequence alignment