Detailed information NTG0717616

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: NUU05_RS02530
• Genome accession: NZ_CP102538
• Coordinates: 463721..465874 (+)
• Length: 717 a.a.
• NCBI ID: WP_041827772.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain TH-4
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 458721..470874

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NUU05_RS02515 (NUU05_02505)	-	458817..459023 (+)	207	WP_011681579.1	hypothetical protein	-
NUU05_RS02520 (NUU05_02510)	-	459332..460969 (+)	1638	WP_232991507.1	ABC transporter ATP-binding protein	-
NUU05_RS02525 (NUU05_02515)	-	460962..462707 (+)	1746	WP_011681577.1	ABC transporter ATP-binding protein	-
NUU05_RS02530 (NUU05_02520)	comA/nlmT	463721..465874 (+)	2154	WP_041827772.1	peptide cleavage/export ABC transporter	Regulator
NUU05_RS02535 (NUU05_02525)	-	465890..467257 (+)	1368	WP_011681574.1	bacteriocin secretion accessory protein	-
NUU05_RS02540 (NUU05_02530)	-	467272..467433 (+)	162	WP_011681573.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
NUU05_RS02545 (NUU05_02535)	-	467451..468254 (-)	804	WP_223899638.1	ATP-binding protein	-
NUU05_RS02550 (NUU05_02540)	-	468785..469522 (-)	738	WP_011681571.1	LytTR family DNA-binding domain-containing protein	-
NUU05_RS02555 (NUU05_02545)	-	469773..469949 (+)	177	WP_011681570.1	Blp family class II bacteriocin	-
NUU05_RS02560 (NUU05_02550)	-	469968..470168 (+)	201	WP_011681569.1	hypothetical protein	-
NUU05_RS02565 (NUU05_02555)	-	470524..470754 (+)	231	WP_011226494.1	bacteriocin class II family protein	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80658.47 Da
• Isoelectric Point: 6.8843

>NTDB_id=717616 NUU05_RS02530 WP_041827772.1 463721..465874(+) (comA/nlmT) [Streptococcus thermophilus strain TH-4]
MFRFRRTFVPQIDMRDCGVAALASVAKYYGSDYSLAHLRELAKTNKEGTTALGLVEAAKKIGFETRAIKAEMSLFEMEDV
PYPFIAHVNKDGKLQHYYVIYKSTKDYLIIGDPDPSVKVTKMTKERFEKEWTGITLFMGPEPSYKPHKDKKNGLWDFLPL
IFKQRSLIANIVFASLLVTLINILGSYYLQGILDEYVPNQMKSTLGIISIGLVVTYVLQQMMTFARDYLLTILSQRFTID
VILSYIRHIFELPMSFFATRRTGEVISRFSDANSIIDALASTILSLFLDFSIVIIVGGVLLIQNSNLFKLVLCSVPIYTL
IVFAFMKPFERMNHDVMQSNAMVNSAIIEDINGIETIKSLTSEEVCYQKIDGEFIDYLDNSFRLSKLSILQTSLKQGAQL
ILNVLILWTGAQLVMGNTISIGQLITFNMLLSYFTNPLENIINLQTKLQSAKVANTRLNEVYLIESEFGQSDDTYQEGIA
DGDITVTDLSYKYGFGRDTLTDVSLTIRQGEKISFVGVSGSGKTTLAKMLVNFYQPYKGHIDFNGQNISRIDKKTLRQHI
NYLPQQSYIFSGSVLENLTLGAARGITQADILKACEIAEIRQDIENMPMGFQTELSDGAGLSGGQKQRIALARALLTKSP
VLILDEATSGLDVLTEKQVIDNLLALKDKTIIFVAHRLSIAERTDRIVVIDHGRVVETGSHQDLMSYPGFYYQLFRK

Nucleotide

• Length: 2154 bp

>NTDB_id=717616 NUU05_RS02530 WP_041827772.1 463721..465874(+) (comA/nlmT) [Streptococcus thermophilus strain TH-4]
ATGTTTCGTTTTCGTAGGACTTTTGTCCCTCAAATAGACATGAGGGATTGTGGAGTTGCTGCCTTGGCATCAGTGGCCAA
GTACTATGGTTCAGATTATTCATTAGCACATCTGCGTGAGTTGGCGAAGACCAATAAAGAAGGGACAACTGCCTTAGGTC
TTGTAGAGGCTGCTAAAAAAATTGGCTTTGAAACGAGAGCTATAAAGGCTGAAATGTCGCTCTTTGAGATGGAAGATGTT
CCTTATCCTTTTATTGCTCATGTTAATAAAGATGGGAAGCTTCAACATTATTATGTTATTTATAAAAGCACCAAGGATTA
TCTGATAATTGGAGACCCTGATCCAAGTGTAAAAGTAACTAAAATGACTAAAGAGCGTTTTGAGAAAGAGTGGACAGGTA
TTACTCTTTTTATGGGACCGGAACCCAGTTATAAACCACATAAGGATAAGAAAAATGGACTCTGGGACTTTCTCCCTTTG
ATCTTTAAACAAAGGTCCTTGATAGCTAATATTGTCTTTGCCAGTCTCTTGGTTACTTTAATAAATATTTTAGGTTCCTA
TTATTTACAAGGTATTCTAGACGAATATGTCCCTAATCAAATGAAGTCTACCTTAGGAATTATCTCAATTGGATTAGTTG
TGACCTATGTTTTACAACAAATGATGACTTTTGCAAGAGATTATCTCTTAACCATACTGAGTCAGCGATTTACCATTGAC
GTTATCTTGTCCTACATACGACATATCTTTGAACTCCCAATGTCTTTTTTTGCCACAAGACGTACAGGGGAGGTTATCTC
ACGTTTTAGTGATGCTAACTCTATTATCGATGCTCTGGCTTCGACGATATTATCACTTTTCCTTGATTTCTCTATTGTGA
TTATCGTAGGAGGCGTGTTATTGATACAAAATAGCAATCTCTTCAAGCTAGTTCTTTGTTCGGTTCCAATTTATACCCTT
ATCGTCTTTGCCTTTATGAAACCTTTTGAGCGAATGAATCATGACGTCATGCAGAGTAATGCTATGGTTAATTCAGCCAT
CATTGAGGACATTAATGGGATTGAAACCATAAAGTCACTAACCAGCGAAGAAGTATGCTATCAAAAGATTGATGGTGAGT
TTATTGACTATCTAGACAATTCTTTTCGCCTTTCTAAGTTATCTATACTACAAACATCATTGAAACAAGGTGCTCAACTT
ATTTTAAATGTACTTATCCTCTGGACAGGTGCTCAGTTGGTGATGGGAAATACCATTTCGATAGGACAATTGATTACTTT
TAATATGTTGCTTTCTTACTTCACGAATCCTTTGGAAAATATCATTAACCTGCAAACCAAGTTACAGTCTGCTAAGGTAG
CTAATACTAGGCTCAATGAGGTCTATCTGATTGAATCAGAGTTTGGACAAAGTGATGATACCTATCAAGAAGGCATTGCG
GATGGAGATATCACTGTTACGGATTTATCTTATAAATATGGTTTTGGTCGTGATACTTTGACTGATGTCAGTTTGACGAT
TAGACAAGGAGAAAAAATCAGTTTTGTTGGTGTCAGTGGATCTGGTAAGACTACTCTAGCTAAAATGTTGGTCAATTTTT
ATCAACCATATAAGGGGCACATAGATTTTAATGGTCAAAATATTAGTCGCATAGACAAGAAAACTCTTCGTCAACATATT
AACTATCTCCCTCAGCAATCCTATATATTTAGTGGTAGTGTTTTAGAAAATCTTACTTTAGGTGCAGCACGGGGTATTAC
GCAAGCTGATATTTTGAAAGCTTGTGAAATAGCAGAAATTCGTCAAGATATTGAAAACATGCCTATGGGGTTTCAGACAG
AGCTGTCTGATGGAGCAGGTCTGTCTGGAGGGCAAAAGCAACGTATCGCTTTGGCGCGTGCACTACTAACGAAATCTCCT
GTACTAATCTTAGATGAAGCAACTAGCGGATTGGATGTTTTGACAGAAAAGCAGGTTATTGATAACCTCCTAGCACTAAA
AGATAAAACGATCATCTTTGTAGCACACAGGCTTAGTATCGCTGAGCGGACCGACCGTATCGTAGTCATTGATCACGGAC
GCGTAGTGGAGACAGGTTCTCATCAAGACCTAATGTCTTATCCAGGTTTCTATTATCAATTATTTAGAAAGTGA

Domains

Predicted by InterproScan.

• ABC transporter transmembrane region (ABC_membrane) (170-438)

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter (ABC_tran) (500-649)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	67.787	99.582	0.675
comA	Streptococcus mitis NCTC 12261	65.963	99.163	0.654
comA	Streptococcus pneumoniae Rx1	65.541	99.163	0.65
comA	Streptococcus pneumoniae D39	65.541	99.163	0.65
comA	Streptococcus pneumoniae R6	65.541	99.163	0.65
comA	Streptococcus mitis SK321	65.26	99.163	0.647
comA	Streptococcus pneumoniae TIGR4	65.12	99.163	0.646
comA	Streptococcus gordonii str. Challis substr. CH1	64.146	99.582	0.639