Detailed information NTG0717568

Bioinformatically predicted

Overview

• Name: comGB
• Type: Machinery gene
• Locus tag: MGCS36044_RS00790
• Genome accession: NZ_CP117287
• Coordinates: 127703..128734 (+)
• Length: 343 a.a.
• NCBI ID: WP_084916952.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain MGCS36044
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 122703..133734

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGCS36044_RS00780 (MGCS36044_00318)	-	126380..126745 (+)	366	WP_003055257.1	DUF1033 family protein	-
MGCS36044_RS00785 (MGCS36044_00320)	comGA/cglA	126826..127767 (+)	942	WP_014611930.1	competence type IV pilus ATPase ComGA	Machinery gene
MGCS36044_RS00790 (MGCS36044_00322)	comGB	127703..128734 (+)	1032	WP_084916952.1	competence type IV pilus assembly protein ComGB	Machinery gene
MGCS36044_RS00795 (MGCS36044_00324)	comGC	128736..129062 (+)	327	WP_084916953.1	competence type IV pilus major pilin ComGC	Machinery gene
MGCS36044_RS00800 (MGCS36044_00326)	comGD	129037..129465 (+)	429	WP_257638821.1	competence type IV pilus minor pilin ComGD	Machinery gene
MGCS36044_RS00805 (MGCS36044_00328)	comGE	129422..129718 (+)	297	WP_080982572.1	competence type IV pilus minor pilin ComGE	Machinery gene
MGCS36044_RS00810 (MGCS36044_00330)	comGF	129699..130139 (+)	441	WP_003061780.1	competence type IV pilus minor pilin ComGF	Machinery gene
MGCS36044_RS00815 (MGCS36044_00332)	comGG	130168..130491 (+)	324	WP_227985720.1	competence type IV pilus minor pilin ComGG	-
MGCS36044_RS00820 (MGCS36044_00334)	comGH	130554..131507 (+)	954	WP_003060701.1	class I SAM-dependent methyltransferase	Machinery gene
MGCS36044_RS00825 (MGCS36044_00336)	-	131566..132762 (+)	1197	WP_275902589.1	acetate kinase	-
MGCS36044_RS00830 (MGCS36044_00338)	-	133069..133275 (+)	207	WP_003058508.1	helix-turn-helix transcriptional regulator	-

Sequence

Protein

• Length: 343 a.a.
• Molecular weight: 38965.39 Da
• Isoelectric Point: 9.2055

>NTDB_id=717568 MGCS36044_RS00790 WP_084916952.1 127703..128734(+) (comGB) [Streptococcus dysgalactiae subsp. equisimilis strain MGCS36044]
MTFLQRDISVRSKQGLKKLSSKEQYKLIQLLANLLLTGFNLAEIIAFLTKSHLIPEPYVLRMEEALLKGRGLADMLAGIG
FSDAILTQISLADGHGNIETTLVNIQGYLNQMAKLKRKTIEVVTYPIILLVFLFVMILGLRHYVMPQLEAQNQLTIFLTH
FPAIFFGIILFIGVLLGGIWLHWRSQSRLKLFIHFSAYPVLGKLLQQYLTAYYAREWGTLIGQGLELPVILDIMAMEKSL
FMQELAEDIRVSLLAGQAFHDKVATYPFFKKELSLMITYGEIKSKLGSELEIYAQESWTQFFSQLHQATQFIQPIIFLVI
ALTIVMIYAAILLPIYQNMGGVL

Nucleotide

• Length: 1032 bp

>NTDB_id=717568 MGCS36044_RS00790 WP_084916952.1 127703..128734(+) (comGB) [Streptococcus dysgalactiae subsp. equisimilis strain MGCS36044]
ATGACCTTCTTGCAGCGGGACATCTCAGTCCGGAGCAAGCAAGGTTTGAAAAAATTATCCAGTAAGGAACAATACAAACT
AATTCAGCTATTAGCTAACCTTTTGTTAACAGGATTTAACTTGGCTGAGATAATAGCTTTCTTAACAAAAAGTCATTTGA
TTCCCGAGCCCTATGTTCTCCGCATGGAAGAAGCACTCTTAAAAGGTCGAGGGCTGGCAGATATGTTAGCTGGGATAGGT
TTTTCGGATGCTATTTTAACTCAAATTAGTTTAGCAGATGGTCACGGAAACATTGAGACGACGCTTGTTAATATTCAGGG
CTATCTCAACCAAATGGCTAAACTTAAACGAAAAACCATTGAAGTCGTCACCTATCCGATTATTCTCCTGGTATTTCTTT
TTGTGATGATATTAGGGTTAAGGCATTATGTTATGCCTCAATTAGAAGCTCAAAATCAGCTTACTATTTTTCTGACTCAT
TTTCCAGCTATTTTCTTTGGTATTATCCTTTTTATAGGTGTGCTGTTAGGGGGAATTTGGCTGCATTGGCGATCGCAAAG
TCGCCTCAAGCTTTTTATTCACTTCAGTGCTTATCCTGTTTTAGGGAAACTCTTACAACAGTATCTGACGGCTTATTATG
CTAGAGAATGGGGAACATTGATTGGACAGGGACTTGAATTACCAGTCATTCTGGATATTATGGCCATGGAGAAATCTTTA
TTCATGCAAGAATTGGCTGAAGATATTCGAGTTAGTTTATTGGCAGGACAAGCTTTTCATGATAAGGTAGCTACCTATCC
TTTCTTTAAAAAAGAGTTAAGTTTGATGATTACTTATGGAGAGATTAAATCCAAGTTAGGAAGTGAACTAGAGATTTATG
CTCAAGAGAGTTGGACTCAGTTTTTCAGCCAACTTCATCAAGCAACTCAGTTTATTCAACCGATTATCTTTTTAGTGATT
GCTCTGACGATTGTCATGATTTATGCAGCAATTTTATTACCAATTTATCAAAATATGGGAGGCGTTTTATAA

Domains

Predicted by InterProScan.

• Type II secretion system (T2SS), protein F (T2SSF) (28-146)

• Type II secretion system (T2SS), protein F (T2SSF) (214-334)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGB	Streptococcus mutans UA140	53.392	98.834	0.528
comGB	Streptococcus mutans UA159	53.392	98.834	0.528
comGB	Streptococcus gordonii str. Challis substr. CH1	48.673	98.834	0.481
comGB/cglB	Streptococcus mitis NCTC 12261	45.97	97.668	0.449
comGB/cglB	Streptococcus mitis SK321	45.345	97.085	0.44
comGB/cglB	Streptococcus pneumoniae Rx1	43.844	97.085	0.426
comGB/cglB	Streptococcus pneumoniae D39	43.844	97.085	0.426
comGB/cglB	Streptococcus pneumoniae R6	43.844	97.085	0.426
comGB/cglB	Streptococcus pneumoniae TIGR4	43.844	97.085	0.426
comGB	Lactococcus lactis subsp. cremoris KW2	42.478	98.834	0.42