Detailed information NTG0071601

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: K6K39_RS19125
• Genome accession: NZ_AP024135
• Coordinates: 4289786..4290910 (-)
• Length: 374 a.a.
• NCBI ID: WP_059251644.1
• Uniprot ID: A0ABP5NLL6
• Organism: Streptomyces sp. EAS-AB2608 strain NBRC 114648
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 4284786..4295910

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K6K39_RS19100 (EASAB2608_03914)	cseB	4285492..4286196 (-)	705	WP_059251637.1	two-component system response regulator CseB	-
K6K39_RS19105 (EASAB2608_03915)	-	4286263..4286859 (-)	597	WP_059251638.1	hypothetical protein	-
K6K39_RS19110 (EASAB2608_03916)	-	4286901..4287440 (-)	540	WP_055703482.1	SigE family RNA polymerase sigma factor	-
K6K39_RS19115 (EASAB2608_03917)	-	4287716..4288591 (-)	876	WP_059251641.1	A/G-specific adenine glycosylase	-
K6K39_RS19120 (EASAB2608_03918)	-	4288771..4289598 (+)	828	WP_208639868.1	hypothetical protein	-
K6K39_RS19125 (EASAB2608_03919)	disA	4289786..4290910 (-)	1125	WP_059251644.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
K6K39_RS19130 (EASAB2608_03920)	radA/sms	4290991..4292400 (-)	1410	WP_059251646.1	DNA repair protein RadA	Machinery gene
K6K39_RS19135 (EASAB2608_03921)	-	4292620..4294524 (+)	1905	WP_221334656.1	BACON domain-containing protein	-
K6K39_RS19140 (EASAB2608_03922)	-	4295056..4295889 (-)	834	WP_059251650.1	hypothetical protein	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 39940.64 Da
• Isoelectric Point: 4.9201

>NTDB_id=71601 K6K39_RS19125 WP_059251644.1 4289786..4290910(-) (disA) [Streptomyces sp. EAS-AB2608 strain NBRC 114648]
MAANDRAAAPGKSGGSAGSDGLMRASLSAVAPGTALRDGLERVLRGNTGGLIVLGSDKTVEAMCTGGFVLDVEFTATRLR
ELCKLDGGIVLSSDLSKILRAGVQLVPDPTIPTEETGTRHRTADRVSKQVGFPVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLEELIA
GVEPDRELVVRDYVPEPTAKRSRTVDEALAELDALTHAELLELGTVARALGYTGSPETLDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=71601 K6K39_RS19125 WP_059251644.1 4289786..4290910(-) (disA) [Streptomyces sp. EAS-AB2608 strain NBRC 114648]
GTGGCAGCCAACGACCGGGCAGCAGCTCCCGGAAAGTCCGGTGGGAGTGCCGGTTCCGATGGCCTGATGCGCGCCTCGCT
GAGCGCCGTGGCTCCCGGTACGGCCCTGCGTGACGGCCTGGAGCGGGTCCTGCGCGGCAACACCGGCGGGCTCATCGTGC
TCGGCTCCGACAAGACGGTCGAGGCGATGTGCACGGGCGGTTTCGTGCTGGACGTCGAGTTCACCGCCACCCGGCTGCGG
GAGCTGTGCAAGCTGGACGGCGGCATCGTGCTGTCGTCGGACCTGTCGAAGATCCTGCGCGCGGGCGTCCAGCTGGTCCC
GGACCCGACGATCCCCACGGAGGAGACGGGCACCCGGCACCGCACGGCGGACCGGGTGAGCAAGCAGGTCGGCTTCCCGG
TGGTCTCGGTCTCCCAGTCGATGCGGCTGATCGCCCTGTACGTGGACGGTCAGCGCCGCGTCCTGGAGGACTCGGCGGCG
ATCCTGTCCCGCGCGAACCAGGCGCTGGCGACCCTGGAGCGGTACAAGCTCCGGCTGGACGAGGTCGCGGGCACGCTGTC
GGCGCTGGAGATCGAGGACCTGGTGACGGTCCGGGACGTGTCGGCGGTCGCGCAGCGGCTGGAGATGGTCCGCCGCATCG
CCACCGAGATCGCCGAGTACGTGGTCGAGCTGGGCACGGACGGCCGGCTTCTCGCACTTCAGCTGGAGGAGTTGATCGCC
GGGGTCGAGCCCGACCGCGAGCTGGTGGTCCGGGACTACGTCCCCGAGCCGACGGCGAAGCGGTCCCGCACGGTCGACGA
GGCGCTGGCCGAGCTGGACGCCCTGACCCACGCGGAACTTCTCGAACTGGGCACGGTGGCGCGGGCGCTGGGCTACACCG
GGTCCCCCGAGACGCTCGACTCCGCGGTGTCGCCGCGCGGCTTCCGCCTCCTGGCCAAGGTGCCGCGGCTGCCGGGCGCC
ATCATCGACCGGCTGGTGGAGCACTTCGGGGGGCTGCAGAAGCTGCTCGCCGCGAGCGTGGACGACCTGCAGACCGTCGA
CGGCGTGGGCGAGGCCCGGGCGAGGAGCGTACGGGAGGGGCTGTCGCGCCTGGCCGAGTCCTCCATCCTGGAGCGGTACG
TCTGA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	46.532	92.513	0.43