Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrA   Type   Machinery gene
Locus tag   K6K39_RS07025 Genome accession   NZ_AP024135
Coordinates   1623344..1626373 (-) Length   1009 a.a.
NCBI ID   WP_221334147.1    Uniprot ID   -
Organism   Streptomyces sp. EAS-AB2608 strain NBRC 114648     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1618344..1631373
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6K39_RS07005 (EASAB2608_01462) - 1619257..1620201 (+) 945 WP_086697288.1 hypothetical protein -
  K6K39_RS07010 (EASAB2608_01463) - 1620260..1620688 (-) 429 WP_059248704.1 Rieske (2Fe-2S) protein -
  K6K39_RS07015 (EASAB2608_01464) - 1621148..1622278 (+) 1131 WP_094374356.1 LacI family DNA-binding transcriptional regulator -
  K6K39_RS07020 (EASAB2608_01465) - 1622275..1623195 (+) 921 WP_221334146.1 carbohydrate kinase -
  K6K39_RS07025 (EASAB2608_01466) uvrA 1623344..1626373 (-) 3030 WP_221334147.1 excinuclease ABC subunit UvrA Machinery gene
  K6K39_RS07030 (EASAB2608_01467) - 1626598..1627284 (+) 687 WP_086696648.1 maleylpyruvate isomerase family mycothiol-dependent enzyme -
  K6K39_RS07035 (EASAB2608_01468) - 1627355..1628011 (+) 657 WP_059248709.1 MBL fold metallo-hydrolase -
  K6K39_RS07040 (EASAB2608_01469) - 1628531..1629415 (+) 885 WP_059248710.1 ABC transporter substrate-binding protein -
  K6K39_RS07045 (EASAB2608_01470) - 1629412..1630341 (+) 930 WP_059248711.1 amino acid ABC transporter permease -
  K6K39_RS07050 (EASAB2608_01471) - 1630409..1631137 (+) 729 WP_059254901.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 1009 a.a.        Molecular weight: 110594.64 Da        Isoelectric Point: 7.5914

>NTDB_id=71575 K6K39_RS07025 WP_221334147.1 1623344..1626373(-) (uvrA) [Streptomyces sp. EAS-AB2608 strain NBRC 114648]
MADRLIVRGAREHNLKNVSLDLPRDSLIVFTGLSGSGKSSLAFDTIFAEGQRRYVESLSSYARQFLGQMDKPDVDFIEGL
SPAVSIDQKSTSRNPRSTVGTITEVYDYLRLLFARIGKPHCPECGRPISRQSPQAIVDKVLELPEGSRFQVLSPLVRERK
GEFVDLFADLQTKGYSRARVDGQTIQLSDPPTLKKQEKHTIEVVVDRLTVKDSAKRRLTDSVETALGLSGGMVVLDFVDL
PEDDPERERMYSEHLYCPYDDLSFEELEPRSFSFNSPFGACPECTGIGTRMEVDPELIVPDEDKSLDEGAIHPWSHGHTK
DYFGRLIGALADALGFRTDIPFAGLPQRAKKALLYGHKTQIEVRYRNRYGRERVYTTPFEGAVPFVKRRHSEAESDASRE
RFEGYMREVPCPSCEGTRLKPIVLAVTIMGKSIAEVSAMSISDCAEFLGELKLSARDKKIAERVLKEVNERLRFLVDVGL
DYLSLNRAAGTLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLHQRDNHRLIETLVRLRDMGNTLIVVEHDEDTIKVAD
WIVDIGPGAGEHGGKVVHSGSVKELLANTESQTGAYLSGRKSIPLPDVRRPIDPSRQLTVHGARENNLQDIDVSFPLGVF
TAVTGVSGSGKSTLVNDILYTHLARELNGARTVPGRHTRVDGDDLVDKVVHVDQSPIGRTPRSNPATYTGVFDHIRKLFA
ETTEAKVRGYQPGRFSFNVKGGRCENCAGDGTIKIEMNFLPDVYVPCEVCHGARYNRETLEVHYKGKSIAEVLNMPIEEA
MHFFEAVPGISRHLKTLNDVGLGYVRLGQSATTLSGGEAQRVKLASELQKRSTGRTVYVLDEPTTGLHFEDISKLLTVLG
GLVDKGNTVIVIEHNLDVIKTADWIVDMGPEGGAGGGLVVAEGTPEEVAGVPASHTGKFLREILGADRISDAEPVKAQRG
GTARKKTAAARSTAKKTVTAKANSTATKKAATAAKKATPAKKTTRARKA

Nucleotide


Download         Length: 3030 bp        

>NTDB_id=71575 K6K39_RS07025 WP_221334147.1 1623344..1626373(-) (uvrA) [Streptomyces sp. EAS-AB2608 strain NBRC 114648]
GTGGCCGACCGTCTCATCGTCCGTGGCGCGCGCGAGCACAACCTGAAGAATGTCTCGCTCGACCTGCCTCGTGACTCGCT
CATCGTCTTCACGGGCCTGTCCGGGTCGGGCAAGTCCTCCCTGGCCTTCGACACGATCTTCGCCGAGGGCCAGCGTCGCT
ACGTGGAGTCGCTCTCCTCGTACGCACGGCAGTTCCTCGGCCAGATGGACAAGCCCGACGTCGACTTCATCGAAGGCCTC
TCCCCGGCGGTCTCCATCGACCAGAAGTCGACCTCGCGCAACCCGCGCTCGACGGTCGGCACGATCACCGAGGTCTACGA
CTACCTGCGCCTGCTCTTCGCGCGCATCGGCAAGCCGCACTGCCCCGAGTGCGGCCGTCCGATCTCGCGCCAGTCGCCGC
AGGCCATCGTGGACAAGGTGCTGGAGCTGCCGGAGGGCAGCCGCTTCCAGGTGCTGTCCCCCCTGGTCCGCGAGCGCAAG
GGCGAGTTCGTCGACCTCTTCGCCGACCTGCAGACCAAGGGCTACTCCCGCGCGCGCGTGGACGGCCAGACCATCCAGCT
GTCCGATCCGCCGACGCTGAAGAAGCAGGAGAAGCACACCATCGAGGTGGTCGTGGACCGCCTCACGGTGAAGGACTCCG
CCAAGCGCCGCCTCACCGACTCCGTGGAGACCGCCCTCGGCCTGTCCGGCGGCATGGTCGTGCTCGACTTCGTGGACCTC
CCCGAGGACGATCCCGAGCGCGAGCGCATGTACTCGGAGCACCTGTACTGCCCGTACGACGACCTGTCCTTCGAGGAGCT
GGAGCCCCGCTCCTTCTCCTTCAACTCGCCCTTCGGCGCCTGCCCCGAGTGCACCGGCATCGGCACGCGCATGGAGGTCG
ACCCGGAGCTGATCGTCCCGGACGAGGACAAGTCCCTGGACGAGGGTGCCATCCACCCCTGGTCGCACGGACACACCAAG
GACTACTTCGGCCGCCTGATCGGTGCCCTCGCGGACGCCCTCGGTTTCCGCACGGACATCCCCTTCGCGGGTCTGCCGCA
GCGGGCGAAGAAGGCCCTGCTCTACGGCCACAAGACCCAGATCGAGGTGCGCTACCGCAACCGGTACGGCCGGGAGCGCG
TCTACACCACCCCCTTCGAGGGCGCGGTCCCCTTCGTCAAGCGCCGGCACAGCGAGGCCGAGAGCGACGCCAGCCGCGAG
CGCTTCGAGGGCTACATGCGCGAGGTGCCCTGCCCGTCCTGCGAGGGGACGCGCCTGAAGCCGATCGTCCTGGCGGTCAC
GATCATGGGCAAGTCGATCGCCGAGGTCTCCGCGATGTCGATCAGCGACTGCGCGGAGTTCCTGGGCGAGCTGAAGCTGA
GCGCCCGTGACAAGAAGATCGCCGAGCGGGTTCTCAAGGAGGTCAACGAGCGGCTGCGCTTCCTGGTCGACGTCGGCCTG
GACTACCTCTCGCTCAACCGCGCGGCCGGCACCCTCTCCGGCGGCGAGGCCCAGCGCATCCGGCTGGCCACCCAGATCGG
CTCCGGCCTCGTCGGCGTCCTGTACGTCCTGGACGAGCCGTCCATCGGTCTGCACCAGCGGGACAACCACCGCCTGATCG
AGACCCTGGTGCGGCTGCGTGACATGGGCAACACGCTCATCGTCGTGGAGCACGACGAGGACACCATCAAGGTCGCCGAC
TGGATCGTGGACATCGGCCCCGGCGCCGGCGAGCACGGCGGCAAGGTCGTGCACAGCGGCTCCGTGAAGGAGCTGCTCGC
CAACACCGAGTCGCAGACCGGTGCCTACCTCTCGGGCCGCAAGTCGATTCCGCTTCCGGACGTACGGCGCCCCATCGACC
CGTCCCGCCAGCTCACCGTGCACGGCGCCCGGGAGAACAACCTGCAGGACATCGACGTGTCCTTCCCGCTGGGTGTGTTC
ACGGCCGTCACCGGCGTCTCCGGCTCCGGCAAGTCGACCCTGGTCAACGACATCCTGTACACGCACCTGGCTCGCGAGCT
GAACGGCGCCCGCACCGTCCCCGGACGGCACACGCGCGTGGACGGCGACGACCTGGTCGACAAGGTCGTGCACGTCGACC
AGTCGCCGATCGGCCGCACCCCGCGGTCCAACCCGGCGACGTACACCGGTGTCTTCGACCACATCCGCAAGCTGTTCGCC
GAGACCACCGAGGCGAAGGTCCGCGGCTACCAGCCCGGCCGCTTCTCCTTCAACGTCAAGGGCGGTCGCTGCGAGAACTG
CGCGGGCGACGGCACGATCAAGATCGAGATGAACTTCCTCCCGGACGTCTACGTCCCGTGCGAGGTCTGCCACGGCGCCC
GGTACAACCGGGAGACCCTGGAGGTCCACTACAAGGGCAAGTCCATCGCCGAGGTCCTGAACATGCCGATCGAGGAGGCC
ATGCACTTCTTCGAGGCGGTCCCGGGGATCTCCCGTCACCTGAAGACGCTGAACGACGTCGGTCTCGGCTACGTCCGCCT
CGGCCAGTCCGCCACCACGCTCTCCGGTGGTGAGGCGCAGCGCGTCAAGCTCGCCAGCGAACTGCAGAAGCGGTCCACCG
GACGCACGGTCTACGTCCTGGACGAGCCGACCACCGGTCTGCACTTCGAAGACATCAGCAAGCTGCTGACGGTCCTCGGC
GGACTGGTCGACAAGGGCAACACGGTCATCGTCATCGAGCACAACCTCGACGTGATCAAGACCGCCGACTGGATCGTGGA
CATGGGGCCGGAGGGCGGCGCGGGCGGTGGCCTGGTGGTCGCCGAGGGCACGCCGGAGGAGGTCGCCGGGGTCCCGGCGA
GCCACACCGGCAAGTTCCTGCGCGAGATCCTCGGCGCCGACCGCATCAGCGACGCCGAACCGGTCAAGGCGCAGCGGGGC
GGCACGGCCCGGAAGAAGACGGCCGCGGCCAGGTCGACGGCGAAGAAGACGGTGACGGCCAAGGCCAACAGCACCGCGAC
CAAGAAGGCCGCCACGGCCGCGAAGAAGGCGACGCCCGCGAAGAAGACCACGCGGGCCCGCAAGGCCTGA

Domains

Predicted by InterProScan.

ABC transporter (ABC_tran)

(628-864)

UvrA interaction domain (UvrA_inter)

(131-238)

UvrA DNA-binding domain (UvrA_DNA-bind)

(294-403)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrA Streptococcus pneumoniae R6

57.037

93.657

0.534
  uvrA Streptococcus pneumoniae TIGR4

57.037

93.657

0.534
  uvrA Streptococcus pneumoniae D39

57.037

93.657

0.534

Multiple sequence alignment