Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   NQZ88_RS06140 Genome accession   NZ_CP102152
Coordinates   1212869..1214248 (-) Length   459 a.a.
NCBI ID   WP_257116182.1    Uniprot ID   -
Organism   Streptococcus suis strain DNS11     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1207869..1219248
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NQZ88_RS06115 (NQZ88_06115) - 1208377..1208967 (-) 591 WP_023369994.1 class I SAM-dependent methyltransferase -
  NQZ88_RS06120 (NQZ88_06120) coaA 1209076..1209996 (+) 921 WP_002935283.1 type I pantothenate kinase -
  NQZ88_RS06125 (NQZ88_06125) rpsT 1210055..1210303 (+) 249 WP_012027069.1 30S ribosomal protein S20 -
  NQZ88_RS06130 (NQZ88_06130) tnpA 1210477..1210950 (+) 474 WP_024378560.1 IS200/IS605 family transposase -
  NQZ88_RS06135 (NQZ88_06135) - 1211316..1212545 (-) 1230 WP_023369936.1 transglutaminase domain-containing protein -
  NQZ88_RS06140 (NQZ88_06140) ciaH 1212869..1214248 (-) 1380 WP_257116182.1 cell wall metabolism sensor histidine kinase WalK Regulator
  NQZ88_RS06145 (NQZ88_06145) ciaR 1214241..1214912 (-) 672 WP_009909965.1 response regulator transcription factor Regulator
  NQZ88_RS06150 (NQZ88_06150) - 1215106..1215486 (-) 381 WP_023369940.1 hypothetical protein -
  NQZ88_RS06155 (NQZ88_06155) phoU 1215652..1216308 (-) 657 WP_002937611.1 phosphate signaling complex protein PhoU -
  NQZ88_RS06160 (NQZ88_06160) pstB 1216337..1217095 (-) 759 WP_074389058.1 phosphate ABC transporter ATP-binding protein PstB -
  NQZ88_RS06165 (NQZ88_06165) pstB 1217107..1217910 (-) 804 WP_002940866.1 phosphate ABC transporter ATP-binding protein PstB -
  NQZ88_RS06170 (NQZ88_06170) pstA 1217935..1218822 (-) 888 WP_002937616.1 phosphate ABC transporter permease PstA -

Sequence

Protein


Download         Length: 459 a.a.        Molecular weight: 51996.66 Da        Isoelectric Point: 6.1922

>NTDB_id=715057 NQZ88_RS06140 WP_257116182.1 1212869..1214248(-) (ciaH) [Streptococcus suis strain DNS11]
MPKRFKKLMYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQNSDNTLKRIKKEPALAVGFAIARTYEPNSVFIFQD
SPTGEETTSSSSDSMPVPKNQKNTRAGDQLRLGANTHVLLYSKSGEMINPDTFTGLADLSLDKEKLGEIKETTVESSFGM
SEDYRYITIGLATDELGYYSSYDIKYATILVNVSQIKSSIESYEATVAIVMVSAWLISILASIYLSNLSMRPILISYQKQ
KDFVENASHELRTPLAVLQNRLESLFRHPETTILESSESIGSSLEEVRNMRLLTTNLLNLARRDDGLKVDMIDVQPNYFD
EIFANYLMIAEENGKTLTVNNLIHQPIRTDKVLIKQLLTILFDNAMKYTDEDGTIQIAANIKDKLVCFTVIDNGLGISDT
DKKEIFDRFYRVDKARTRQKGGFGLGLSLAQQIIKNLDGEISVRDNQPKGTIFEVRLPK

Nucleotide


Download         Length: 1380 bp        

>NTDB_id=715057 NQZ88_RS06140 WP_257116182.1 1212869..1214248(-) (ciaH) [Streptococcus suis strain DNS11]
ATGCCTAAGCGATTTAAAAAATTAATGTACACAGATAAATTTTCTTTCTTTATCCGTTATTTTGCAGTATTTACTCTGAT
TTTTGGTTTAATGACAGCCATCATTTTTCAATTAATGCGTTCAACTATGTACCAAAATTCAGATAACACCTTGAAACGCA
TTAAGAAAGAACCAGCGCTGGCTGTTGGTTTTGCAATCGCAAGAACCTATGAGCCCAATTCTGTATTTATCTTTCAAGAT
AGTCCAACTGGTGAAGAAACTACGAGCTCTAGTTCAGATAGCATGCCTGTTCCTAAAAATCAAAAAAATACTAGAGCTGG
AGATCAGCTGAGATTAGGTGCCAATACTCATGTTTTACTCTATAGTAAAAGTGGAGAGATGATTAATCCAGATACTTTTA
CTGGTTTGGCCGACCTATCATTAGACAAGGAAAAATTGGGTGAAATTAAGGAAACTACGGTTGAATCAAGTTTTGGTATG
TCTGAAGATTATCGCTATATAACGATTGGGCTGGCTACAGATGAACTAGGTTATTATTCGTCCTATGATATAAAATATGC
GACAATTTTGGTGAATGTCAGCCAAATTAAATCTTCCATTGAGAGCTATGAAGCGACAGTTGCTATTGTTATGGTATCAG
CTTGGTTGATTTCTATACTAGCAAGTATTTACCTATCGAATCTTAGCATGCGTCCAATCCTAATTAGTTATCAAAAACAA
AAAGACTTCGTTGAAAATGCTAGTCATGAGTTACGCACACCGTTGGCAGTTCTTCAAAATCGCCTGGAAAGTCTATTTCG
TCATCCCGAGACAACTATTTTGGAAAGTAGTGAAAGCATCGGATCTAGTTTAGAAGAAGTTCGAAATATGCGACTATTGA
CAACAAATTTACTTAATTTGGCTCGTCGTGATGATGGCTTAAAAGTCGATATGATCGATGTCCAACCCAACTATTTTGAT
GAAATCTTTGCTAATTACCTTATGATTGCCGAAGAAAATGGAAAAACTCTAACAGTTAATAATTTGATTCATCAGCCAAT
TCGAACAGACAAGGTTTTGATTAAACAGTTGCTCACCATTTTGTTTGACAACGCTATGAAGTATACCGATGAAGATGGGA
CAATTCAAATAGCAGCTAATATCAAGGACAAACTAGTTTGTTTTACAGTTATTGACAATGGTTTGGGAATCAGCGATACC
GATAAAAAGGAAATCTTTGATCGCTTTTACCGAGTTGACAAGGCTAGAACACGTCAAAAAGGTGGATTTGGTTTAGGTTT
ATCTTTAGCTCAACAAATTATTAAGAATTTAGATGGTGAGATTTCTGTGAGAGATAACCAACCGAAAGGAACTATTTTTG
AGGTACGTTTACCCAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(240-306)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(350-458)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

49.127

99.782

0.49
  ciaH Streptococcus pneumoniae D39

49.127

99.782

0.49
  ciaH Streptococcus pneumoniae R6

49.127

99.782

0.49
  ciaH Streptococcus pneumoniae TIGR4

49.127

99.782

0.49
  ciaH Streptococcus mutans UA159

49.011

99.129

0.486