Detailed information NTG0715054

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: NQZ88_RS04120
• Genome accession: NZ_CP102152
• Coordinates: 792722..794959 (+)
• Length: 745 a.a.
• NCBI ID: WP_074389299.1
• Uniprot ID: A0AAP6DW18
• Organism: Streptococcus suis strain DNS11
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 787722..799959

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NQZ88_RS04095 (NQZ88_04095)	-	787794..788723 (-)	930	WP_023370720.1	ABC transporter substrate-binding protein	-
NQZ88_RS04100 (NQZ88_04100)	-	788720..789520 (-)	801	WP_023370718.1	ABC transporter ATP-binding protein	-
NQZ88_RS04105 (NQZ88_04105)	-	789672..791117 (-)	1446	WP_023370716.1	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	-
NQZ88_RS04110 (NQZ88_04110)	-	791263..792009 (+)	747	WP_023370714.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
NQZ88_RS04115 (NQZ88_04115)	comEA/celA/cilE	792076..792738 (+)	663	WP_023370712.1	helix-hairpin-helix domain-containing protein	Machinery gene
NQZ88_RS04120 (NQZ88_04120)	comEC/celB	792722..794959 (+)	2238	WP_074389299.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
NQZ88_RS04125 (NQZ88_04125)	-	794976..795101 (+)	126	Protein_773	IS982 family transposase	-
NQZ88_RS04130 (NQZ88_04130)	-	795284..795940 (+)	657	WP_011922763.1	CBS domain-containing protein	-
NQZ88_RS04135 (NQZ88_04135)	-	796083..797804 (-)	1722	WP_074389404.1	IS1634 family transposase	-
NQZ88_RS04140 (NQZ88_04140)	-	798009..798836 (+)	828	WP_011922194.1	hypothetical protein	-

Sequence

Protein

• Length: 745 a.a.
• Molecular weight: 84149.21 Da
• Isoelectric Point: 7.9211

>NTDB_id=715054 NQZ88_RS04120 WP_074389299.1 792722..794959(+) (comEC/celB) [Streptococcus suis strain DNS11]
MSRLSKLPCQPIHLALLAVAAYFVVHSFSLLTMGLLSLLLLVFGFRQGKTVFIRTLPLIALCGLFFGYQKVQWERADQLA
PEQVTTVQVIPDTIEVNGDSLSFRGRADGQTYQVFYKLTSQEEQTYFQKLTGLVQLEVEAEISLPAGQRNFKGFDYQAYL
KTQGIYLTVKITAIKKIVPVQSWNVFDWLSNWRRQALVYVKTNFPVPMSHYMTGLLFGDLDSDFDQMSDLYSSLGIIHLF
ALSGMQVGFFIDKFRWILLRLGLTKETVDKLQIPFSLVYASLTGFSVSVVRSLVQKILGNLGLRKLDNFAVTVFVCLLIL
PRFLLTAGGVLTFTYAFLLTVFDFEDLGQVKKAAVESLSISLGILPVLMTYFYAFQPLSILLTFAFSFVFDVLLLPGLSV
IFLLSPIVKITWVNGFFVFMEKIIVWVADLGLRPWILGKPSELVLLLLLVSLFLLYDFHRRKKWLLGLSLVLALLFFITK
HPLENEVTVVDIGQGDSIFLRDMRGRTVLIDVGGRVDFAAKEAWQERSRQANAERTLIPYLHSRGVDRIDSLVLTHTDTD
HVGDVLEVAKQVQIGRIVVSPGSLTVPDFVATLKKINVPVHVVKVGDRLPIFDSYLEVLYPDGTGDGGNNDSIVLYGRLL
ETNFLFTGDLEQGELDLIETYPNLPVDVLKAGHHGSKGSSYPEFLDHIGAKIALVSAGENNRYKHPHQETLERFDSRNIQ
VYRTDQQGAIRFRGWKEWKIETVRR

Nucleotide

• Length: 2238 bp

>NTDB_id=715054 NQZ88_RS04120 WP_074389299.1 792722..794959(+) (comEC/celB) [Streptococcus suis strain DNS11]
ATGTCACGGTTGAGTAAGCTCCCCTGCCAGCCCATCCACTTGGCTCTTTTGGCGGTGGCAGCCTACTTTGTAGTCCACTC
TTTTTCCCTCTTGACAATGGGCCTGCTGAGTTTGTTGTTGCTGGTCTTTGGATTTCGACAAGGTAAGACAGTTTTCATCA
GAACGCTGCCGCTTATAGCCTTATGTGGTCTGTTTTTCGGCTACCAAAAGGTCCAATGGGAGCGGGCAGACCAGTTAGCC
CCAGAGCAAGTGACGACTGTGCAGGTCATTCCAGATACGATTGAAGTCAACGGGGACAGCCTGTCCTTCCGCGGTCGGGC
TGACGGACAAACCTATCAGGTTTTCTATAAATTAACCAGTCAGGAGGAACAGACCTATTTTCAAAAGCTGACAGGTTTGG
TCCAGCTTGAAGTGGAAGCAGAGATCAGTCTGCCAGCTGGTCAGCGGAATTTCAAGGGTTTTGACTATCAGGCCTACCTG
AAAACACAGGGTATTTATCTGACGGTCAAGATTACGGCAATCAAGAAGATTGTCCCAGTCCAGTCTTGGAATGTCTTTGA
CTGGTTGTCAAACTGGCGGAGGCAGGCTTTGGTTTATGTCAAAACCAATTTTCCGGTTCCCATGAGCCACTACATGACAG
GGCTCTTGTTTGGGGACTTGGATAGTGATTTTGACCAGATGAGTGACCTCTATTCCAGTTTGGGTATCATTCATCTCTTT
GCCCTGTCTGGTATGCAGGTGGGCTTTTTCATCGACAAGTTTCGCTGGATTTTACTGCGTTTGGGCTTGACCAAAGAAAC
GGTTGATAAATTACAAATTCCCTTTTCCCTTGTCTATGCGAGCTTGACAGGTTTTTCCGTATCGGTGGTGCGGTCTTTGG
TTCAAAAAATTTTGGGTAATCTGGGCTTGCGGAAGTTGGATAACTTTGCGGTGACAGTTTTTGTCTGTCTGTTGATACTG
CCCCGATTTCTGCTGACAGCTGGTGGTGTCCTGACCTTTACCTATGCTTTTTTGCTGACGGTTTTTGATTTTGAGGACTT
GGGGCAGGTCAAAAAGGCTGCGGTGGAAAGTCTCAGTATTTCACTTGGGATTTTGCCAGTGCTCATGACCTATTTCTATG
CCTTTCAGCCCCTGTCTATCCTCTTGACCTTTGCCTTTTCTTTTGTCTTTGATGTCCTACTCTTGCCAGGCTTGTCAGTC
ATTTTTCTCCTGTCGCCAATCGTCAAGATTACTTGGGTCAACGGATTTTTTGTCTTTATGGAAAAAATCATTGTCTGGGT
GGCGGATTTGGGATTGCGACCTTGGATACTGGGCAAGCCGTCTGAGCTGGTCCTTTTGCTCTTGCTGGTCAGCCTCTTCT
TACTCTACGATTTCCACAGGAGAAAGAAATGGCTTCTAGGACTGAGCTTGGTCCTCGCTCTGCTATTTTTCATAACCAAA
CACCCGCTGGAAAACGAGGTGACGGTGGTGGACATCGGGCAGGGGGACAGCATCTTTTTGCGGGATATGCGGGGGCGGAC
GGTCCTGATTGATGTGGGCGGACGAGTTGATTTTGCGGCCAAGGAAGCGTGGCAGGAGCGGTCTCGGCAGGCAAATGCAG
AGCGGACTTTGATTCCCTATCTGCATAGTCGGGGTGTGGATAGGATTGATAGTTTAGTCCTGACCCACACCGACACAGAC
CATGTGGGGGATGTGCTGGAAGTGGCTAAGCAGGTGCAAATTGGTCGGATTGTCGTGTCGCCAGGAAGTCTGACGGTGCC
TGACTTTGTAGCAACTCTGAAAAAAATCAATGTGCCTGTCCATGTGGTAAAAGTGGGCGACCGCCTACCAATTTTTGACT
CCTATCTGGAGGTCCTCTATCCAGATGGGACAGGCGACGGTGGCAATAATGACTCCATTGTCCTTTACGGTCGCTTGTTG
GAAACTAACTTTCTCTTTACAGGAGACCTGGAGCAAGGGGAGTTGGACTTGATAGAAACCTATCCCAACCTGCCTGTCGA
TGTCCTCAAAGCCGGTCACCATGGCTCCAAAGGCTCTTCTTATCCTGAATTTTTAGACCATATCGGTGCCAAGATTGCCT
TGGTATCTGCTGGAGAAAACAACCGCTACAAGCATCCTCACCAAGAAACCTTGGAACGATTTGACAGCCGGAATATCCAA
GTCTATCGCACAGACCAGCAAGGAGCCATTCGCTTCCGAGGTTGGAAGGAGTGGAAGATTGAGACGGTGAGGAGGTAA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (215-461)

• Metallo-beta-lactamase superfamily (Lactamase_B) (493-698)

• Domain of unknown function (DUF4131) (DUF4131) (28-175)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	54.105	99.732	0.54
comEC/celB	Streptococcus mitis NCTC 12261	53.036	99.463	0.528
comEC/celB	Streptococcus pneumoniae TIGR4	52.156	99.597	0.519
comEC/celB	Streptococcus pneumoniae Rx1	51.887	99.597	0.517
comEC/celB	Streptococcus pneumoniae D39	51.887	99.597	0.517
comEC/celB	Streptococcus pneumoniae R6	51.887	99.597	0.517
comEC	Lactococcus lactis subsp. cremoris KW2	49.13	100	0.493