Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   NQZ88_RS00335 Genome accession   NZ_CP102152
Coordinates   55420..56319 (+) Length   299 a.a.
NCBI ID   WP_074389013.1    Uniprot ID   -
Organism   Streptococcus suis strain DNS11     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 57039..58634 55420..56319 flank 720


Gene organization within MGE regions


Location: 55420..58634
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NQZ88_RS00335 (NQZ88_00335) comR 55420..56319 (+) 900 WP_074389013.1 helix-turn-helix domain-containing protein Regulator
  NQZ88_RS00340 (NQZ88_00340) tnpA 57039..57512 (+) 474 WP_024378560.1 IS200/IS605 family transposase -
  NQZ88_RS00345 (NQZ88_00345) - 57696..58634 (-) 939 WP_257116210.1 IS4 family transposase -

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35432.37 Da        Isoelectric Point: 4.6995

>NTDB_id=715031 NQZ88_RS00335 WP_074389013.1 55420..56319(+) (comR) [Streptococcus suis strain DNS11]
MNDKEFGQRVRQLRESASMTREQFCDDELELSVRQLTRIEAGASKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYGNEDLAEKRDAMMTEIYDDYYDELPEEEKIAIDAIQSRIDTLESGTAGFGKEILEDYFEQIFRKRKYELND
LLIVRLHLEYVRLSSCDSEIFRQFLKIIEHLHEQINIINSNDLFVLRDTLLSCVNILGSKKYYEPIPKIFDSVDKIIQSK
QDFQKKPIVSVLKWKYALFVDKDRDEAEKHYLDAVLFAKLIENRELEQKIEEDWRVDNQ

Nucleotide


Download         Length: 900 bp        

>NTDB_id=715031 NQZ88_RS00335 WP_074389013.1 55420..56319(+) (comR) [Streptococcus suis strain DNS11]
ATGAACGATAAGGAATTTGGACAGCGTGTACGTCAATTACGAGAATCTGCTAGTATGACACGTGAACAGTTTTGTGACGA
TGAACTGGAACTCTCTGTGCGCCAATTAACTCGTATTGAAGCAGGTGCTTCCAAGCCGACTTTTTCAAAGATTCAGTATA
TTGCAACTCGTTTAGGTATGGGACTTTACGAGCTTATGCCAGATTATGTATCTTTACCCGAAAGATATTCCAAGCTGAAG
TTTGATGTGCTTCGCACCCCAACTTATGGTAATGAAGATTTGGCGGAAAAGCGAGATGCCATGATGACAGAAATCTATGA
CGATTATTATGATGAATTGCCTGAGGAGGAGAAGATAGCAATAGATGCGATTCAATCACGAATTGATACTTTAGAGTCAG
GTACAGCAGGCTTTGGAAAAGAGATACTGGAAGACTACTTTGAACAAATTTTTCGCAAACGAAAGTATGAATTGAATGAT
TTGTTGATTGTTAGGCTCCATCTTGAATATGTTAGGTTATCTAGCTGTGATTCAGAAATATTTAGACAGTTTTTGAAAAT
TATAGAGCATTTACATGAGCAAATCAATATCATCAACTCAAATGATTTATTTGTTTTACGAGACACGCTATTATCTTGTG
TAAATATATTAGGAAGTAAAAAATATTACGAACCAATACCAAAGATATTTGACAGTGTAGATAAGATTATACAGTCGAAA
CAAGATTTTCAGAAAAAGCCCATTGTTAGTGTATTAAAATGGAAATATGCACTTTTTGTGGATAAGGATCGGGATGAGGC
AGAAAAGCATTATCTAGATGCGGTGCTATTTGCAAAATTGATAGAAAATAGAGAGTTAGAACAGAAGATTGAAGAAGATT
GGAGAGTTGACAATCAATAA

Domains

Predicted by InterproScan.

ComR tetratricopeptide (ComR_TPR)

(73-294)

Helix-turn-helix domain (HTH_31)

(5-60)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus suis P1/7

99.666

100

0.997
  comR Streptococcus suis 05ZYH33

99.666

100

0.997
  comR Streptococcus suis D9

62.126

100

0.625
  comR Streptococcus mutans UA159

43.478

100

0.435
  comR Streptococcus pyogenes MGAS315

37.374

99.331

0.371