Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   NQZ90_RS04035 Genome accession   NZ_CP102148
Coordinates   820024..821403 (+) Length   459 a.a.
NCBI ID   WP_024385779.1    Uniprot ID   A0AAW9DDT2
Organism   Streptococcus suis strain DNC15     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 815024..826403
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NQZ90_RS04005 (NQZ90_04005) pstA 815450..816337 (+) 888 WP_014635996.1 phosphate ABC transporter permease PstA -
  NQZ90_RS04010 (NQZ90_04010) pstB 816362..817165 (+) 804 WP_002940866.1 phosphate ABC transporter ATP-binding protein PstB -
  NQZ90_RS04015 (NQZ90_04015) pstB 817177..817935 (+) 759 WP_002937614.1 phosphate ABC transporter ATP-binding protein PstB -
  NQZ90_RS04020 (NQZ90_04020) phoU 817964..818620 (+) 657 WP_002937611.1 phosphate signaling complex protein PhoU -
  NQZ90_RS04025 (NQZ90_04025) - 818786..819166 (+) 381 WP_024389002.1 hypothetical protein -
  NQZ90_RS04030 (NQZ90_04030) ciaR 819360..820031 (+) 672 WP_024385291.1 response regulator transcription factor Regulator
  NQZ90_RS04035 (NQZ90_04035) ciaH 820024..821403 (+) 1380 WP_024385779.1 cell wall metabolism sensor histidine kinase WalK Regulator
  NQZ90_RS04040 (NQZ90_04040) - 821503..822732 (+) 1230 WP_024385778.1 transglutaminase domain-containing protein -
  NQZ90_RS04045 (NQZ90_04045) rpsT 822984..823232 (-) 249 WP_012027069.1 30S ribosomal protein S20 -
  NQZ90_RS04050 (NQZ90_04050) coaA 823291..824211 (-) 921 WP_024389003.1 type I pantothenate kinase -
  NQZ90_RS04055 (NQZ90_04055) - 824320..824910 (+) 591 WP_024389004.1 class I SAM-dependent methyltransferase -
  NQZ90_RS04060 (NQZ90_04060) - 824907..826184 (+) 1278 WP_024389005.1 pyrimidine-nucleoside phosphorylase -

Sequence

Protein


Download         Length: 459 a.a.        Molecular weight: 51774.39 Da        Isoelectric Point: 7.3856

>NTDB_id=715010 NQZ90_RS04035 WP_024385779.1 820024..821403(+) (ciaH) [Streptococcus suis strain DNC15]
MPKRIGKLVYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQNSDNTLKRIKKEPALAVGFAIARTYEPNSVFILQD
SPTSEETTSSSSDSMPVPKNQKNTRAGDQLRLGANTHVLLYSKSGEMINPDTFTGLADLSLDKEKLGEIKETTVESSFGM
SEDYRYVTIELATDELGYYSSYDIKYATILVNVSQIKSSIETYESTVAIVMVSAWLISILASIYLSNLSMRPILISYQKQ
KDFVENASHELRTPLAVLQNRLESLFRHPEATILESSESIGSSLEEVRNMRLLTTNLLNLARRDDGLKVDMIDVQPNYFD
EIFANYLMIAEENGKTLTVNNLIHQPIRTDKVLIKQLLTILFDNAMKYTDDDGRIQITANIKDKSVYFTVADNGLGISDA
DKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIIKTLGGKISVRDNQPKGTIFEVGLPK

Nucleotide


Download         Length: 1380 bp        

>NTDB_id=715010 NQZ90_RS04035 WP_024385779.1 820024..821403(+) (ciaH) [Streptococcus suis strain DNC15]
ATGCCTAAGCGAATCGGAAAATTAGTGTATACGGATAAATTTTCCTTCTTTATCCGTTATTTTGCAGTATTTACCCTGAT
TTTTGGCTTGATGACAGCTATCATTTTTCAATTAATGCGTTCAACTATGTACCAAAATTCAGATAACACCTTGAAACGCA
TTAAAAAAGAACCAGCGCTGGCTGTTGGTTTTGCGATCGCAAGAACCTATGAGCCCAACTCTGTCTTTATACTTCAAGAT
AGCCCAACTAGTGAAGAAACAACGAGCTCTAGTTCAGATAGCATGCCTGTTCCTAAAAATCAAAAAAATACTAGAGCTGG
AGATCAGCTGAGATTAGGTGCCAATACTCATGTTTTACTCTATAGTAAAAGTGGAGAGATGATTAATCCAGATACTTTTA
CTGGTTTGGCCGACCTATCATTAGACAAGGAAAAATTGGGTGAAATTAAGGAAACTACGGTTGAATCAAGTTTTGGTATG
TCTGAAGATTATCGCTATGTGACGATTGAGCTGGCTACAGATGAACTAGGTTATTATTCGTCCTATGATATAAAATATGC
GACAATTTTAGTGAATGTCAGCCAAATAAAATCCTCCATTGAGACCTATGAATCGACAGTTGCTATTGTTATGGTTTCAG
CGTGGCTCATTTCTATCTTGGCAAGTATTTACCTATCAAATCTTAGCATGCGTCCAATTCTAATTAGCTATCAAAAGCAA
AAAGACTTTGTTGAAAATGCTAGTCATGAGTTGCGTACGCCGTTGGCTGTTCTCCAAAATCGCTTGGAGAGCCTATTTCG
CCATCCCGAAGCGACGATTTTAGAGAGTAGTGAAAGCATCGGATCTAGTTTAGAAGAAGTCCGAAATATGCGATTATTGA
CAACGAACCTGCTCAATTTGGCTCGTCGTGATGATGGCTTAAAAGTCGATATGATCGATGTCCAACCCAACTATTTTGAT
GAAATCTTTGCTAATTACCTTATGATTGCCGAAGAAAATGGAAAAACACTAACAGTTAATAATTTGATTCATCAGCCGAT
TCGAACAGATAAGGTCCTGATTAAACAGTTGCTTACCATTTTATTTGACAATGCCATGAAGTATACCGACGATGATGGCA
GAATTCAAATTACAGCTAATATCAAGGATAAATCTGTCTACTTCACAGTTGCCGACAATGGTTTGGGAATCAGCGATGCC
GATAAGAAGAAAATCTTTGATCGCTTTTATCGAGTTGATAAGGCCAGAACGCGTCAAAAAGGTGGTTTCGGTCTAGGATT
ATCGCTGGCTCAGCAAATTATTAAGACACTAGGTGGGAAAATCTCTGTTAGAGATAACCAACCGAAAGGAACTATTTTTG
AGGTAGGATTACCTAAATAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(350-458)

His Kinase A (phospho-acceptor) domain (HisKA)

(240-306)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

49.345

99.782

0.492
  ciaH Streptococcus pneumoniae D39

49.345

99.782

0.492
  ciaH Streptococcus pneumoniae R6

49.345

99.782

0.492
  ciaH Streptococcus pneumoniae TIGR4

49.345

99.782

0.492
  ciaH Streptococcus mutans UA159

50.559

97.386

0.492