Detailed information NTG0714847

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: NQZ93_RS05615
• Genome accession: NZ_CP102141
• Coordinates: 1156278..1156949 (-)
• Length: 223 a.a.
• NCBI ID: WP_009909965.1
• Uniprot ID: A0A075SH40
• Organism: Streptococcus suis strain DNR48
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1151278..1161949

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NQZ93_RS05595 (NQZ93_05595)	coaA	1151864..1152784 (+)	921	WP_024381359.1	type I pantothenate kinase	-
NQZ93_RS05600 (NQZ93_05600)	rpsT	1152843..1153091 (+)	249	WP_012027069.1	30S ribosomal protein S20	-
NQZ93_RS05605 (NQZ93_05605)	-	1153353..1154582 (-)	1230	WP_024381360.1	transglutaminase domain-containing protein	-
NQZ93_RS05610 (NQZ93_05610)	ciaH	1154906..1156285 (-)	1380	WP_024381361.1	cell wall metabolism sensor histidine kinase WalK	Regulator
NQZ93_RS05615 (NQZ93_05615)	ciaR	1156278..1156949 (-)	672	WP_009909965.1	response regulator transcription factor	Regulator
NQZ93_RS05620 (NQZ93_05620)	-	1157143..1157298 (-)	156	WP_228380904.1	hypothetical protein	-
NQZ93_RS05625 (NQZ93_05625)	-	1157356..1157490 (-)	135	WP_255304292.1	hypothetical protein	-
NQZ93_RS05630 (NQZ93_05630)	phoU	1157656..1158312 (-)	657	WP_024390542.1	phosphate signaling complex protein PhoU	-
NQZ93_RS05635 (NQZ93_05635)	pstB	1158341..1159099 (-)	759	WP_002937614.1	phosphate ABC transporter ATP-binding protein PstB	-
NQZ93_RS05640 (NQZ93_05640)	pstB	1159111..1159914 (-)	804	WP_002940866.1	phosphate ABC transporter ATP-binding protein PstB	-
NQZ93_RS05645 (NQZ93_05645)	pstA	1159939..1160826 (-)	888	WP_024381362.1	phosphate ABC transporter permease PstA	-
NQZ93_RS05650 (NQZ93_05650)	pstC	1160816..1161733 (-)	918	WP_024381363.1	phosphate ABC transporter permease subunit PstC	-

Sequence

Protein

• Length: 223 a.a.
• Molecular weight: 25290.00 Da
• Isoelectric Point: 4.2183

>NTDB_id=714847 NQZ93_RS05615 WP_009909965.1 1156278..1156949(-) (ciaR) [Streptococcus suis strain DNR48]
MIKILLVEDDLSLSNSVFDFLDDFADVMQVFDGEEGVYEAETGVYDLILLDLMLPEKDGFQVLKELREKGVTTPVLITTA
KESLEDKGHGFELGADDYLTKPFYLEELKMRIQALLKRAGKFNENTLTFGDVTVDLSTNMTMVNGEEVELLGKEFDLLVY
FLQNQNVILPKTQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTTFGENLQTLRSVGYILKNA

Nucleotide

• Length: 672 bp

>NTDB_id=714847 NQZ93_RS05615 WP_009909965.1 1156278..1156949(-) (ciaR) [Streptococcus suis strain DNR48]
ATGATTAAAATATTGTTAGTGGAAGATGATTTAAGCCTATCAAATTCTGTTTTCGATTTCTTAGATGATTTTGCGGATGT
TATGCAGGTTTTTGATGGTGAAGAGGGCGTTTATGAGGCGGAAACAGGCGTTTATGATTTGATTCTTTTGGATTTGATGT
TGCCTGAAAAAGATGGCTTCCAAGTCTTGAAAGAGTTACGTGAAAAGGGGGTTACGACACCAGTTCTGATTACAACAGCC
AAGGAAAGTCTAGAGGATAAAGGCCATGGTTTTGAATTGGGGGCTGATGACTATTTGACAAAACCGTTTTATTTAGAAGA
ATTGAAGATGCGAATTCAAGCTCTATTAAAACGAGCGGGTAAGTTTAATGAAAACACACTAACCTTTGGAGATGTGACAG
TTGACCTATCTACAAATATGACGATGGTAAATGGCGAAGAAGTTGAACTGCTAGGAAAAGAATTTGATCTACTAGTTTAT
TTCTTGCAAAATCAAAATGTCATTTTGCCAAAAACACAAATTTTTGACCGTATTTGGGGCTTTGACAGTGATACTACAAT
TTCAGTAGTAGAAGTATATGTTTCTAAAATTAGGAAAAAGTTGAAAGGAACGACCTTTGGGGAAAATCTTCAAACCCTGC
GTAGTGTCGGATACATTCTAAAAAATGCCTAA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-112)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (145-220)

3D structure

• AlphaFold DB: A0A075SH40

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus mutans UA159	90.135	100	0.901
ciaR	Streptococcus pneumoniae Rx1	88.341	100	0.883
ciaR	Streptococcus pneumoniae D39	88.341	100	0.883
ciaR	Streptococcus pneumoniae R6	88.341	100	0.883
ciaR	Streptococcus pneumoniae TIGR4	88.341	100	0.883
covR	Lactococcus lactis subsp. lactis strain DGCC12653	38.496	100	0.39
vicR	Streptococcus mutans UA159	35.47	100	0.372
covR	Streptococcus salivarius strain HSISS4	35.841	100	0.363