Detailed information NTG0714846

Bioinformatically predicted

Overview

• Name: ciaH
• Type: Regulator
• Locus tag: NQZ93_RS05610
• Genome accession: NZ_CP102141
• Coordinates: 1154906..1156285 (-)
• Length: 459 a.a.
• NCBI ID: WP_024381361.1
• Uniprot ID: A0A075SID2
• Organism: Streptococcus suis strain DNR48
• Function: repress competence development; post-transcriptional repression of CSP production (predicted from homology) Competence regulation

Genomic Context

Location: 1149906..1161285

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NQZ93_RS05590 (NQZ93_05590)	-	1151165..1151755 (-)	591	WP_009909951.1	class I SAM-dependent methyltransferase	-
NQZ93_RS05595 (NQZ93_05595)	coaA	1151864..1152784 (+)	921	WP_024381359.1	type I pantothenate kinase	-
NQZ93_RS05600 (NQZ93_05600)	rpsT	1152843..1153091 (+)	249	WP_012027069.1	30S ribosomal protein S20	-
NQZ93_RS05605 (NQZ93_05605)	-	1153353..1154582 (-)	1230	WP_024381360.1	transglutaminase domain-containing protein	-
NQZ93_RS05610 (NQZ93_05610)	ciaH	1154906..1156285 (-)	1380	WP_024381361.1	cell wall metabolism sensor histidine kinase WalK	Regulator
NQZ93_RS05615 (NQZ93_05615)	ciaR	1156278..1156949 (-)	672	WP_009909965.1	response regulator transcription factor	Regulator
NQZ93_RS05620 (NQZ93_05620)	-	1157143..1157298 (-)	156	WP_228380904.1	hypothetical protein	-
NQZ93_RS05625 (NQZ93_05625)	-	1157356..1157490 (-)	135	WP_255304292.1	hypothetical protein	-
NQZ93_RS05630 (NQZ93_05630)	phoU	1157656..1158312 (-)	657	WP_024390542.1	phosphate signaling complex protein PhoU	-
NQZ93_RS05635 (NQZ93_05635)	pstB	1158341..1159099 (-)	759	WP_002937614.1	phosphate ABC transporter ATP-binding protein PstB	-
NQZ93_RS05640 (NQZ93_05640)	pstB	1159111..1159914 (-)	804	WP_002940866.1	phosphate ABC transporter ATP-binding protein PstB	-
NQZ93_RS05645 (NQZ93_05645)	pstA	1159939..1160826 (-)	888	WP_024381362.1	phosphate ABC transporter permease PstA	-

Sequence

Protein

• Length: 459 a.a.
• Molecular weight: 51961.70 Da
• Isoelectric Point: 6.8882

>NTDB_id=714846 NQZ93_RS05610 WP_024381361.1 1154906..1156285(-) (ciaH) [Streptococcus suis strain DNR48]
MPKRFKKLMYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQNSDNTLKRIKKEPALAVGFAIARTYEPNSVFILQD
SPTGEETTSSSSDSMPVPKNQKNTRAGDQLRLGANTHVLLYSKSGEMINPDTFTGLADLSLDKEKLGEIKETTVESSFGM
SEDYRYITIGLATDELGYYSSYDIKYATILVNVSQIKSSIESYEATVAIVMVSAWLISILASIYLSNLSMRPILISYQKQ
KDFVENASHELRTPLAVLQNRLESLFRHPETTILESSESIGSSLEEVRNMRLLTTNLLNLARRDDGLKVDMIDVQPNYFD
EIFANYLMIAEENGKTLTVNNLIHQPIRTDKVLIKQLLTILFDNAMKYTDEDGTIQIAANIKDKLVCFTVIDNGLGISDT
DKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIIKNLDGEISVRDNQPKGTIFEVRLPK

Nucleotide

• Length: 1380 bp

>NTDB_id=714846 NQZ93_RS05610 WP_024381361.1 1154906..1156285(-) (ciaH) [Streptococcus suis strain DNR48]
ATGCCTAAGCGATTTAAAAAATTAATGTACACGGATAAATTTTCTTTCTTTATCCGTTATTTTGCAGTATTTACTCTGAT
TTTTGGTTTAATGACAGCCATCATTTTTCAATTAATGCGTTCAACTATGTACCAAAATTCAGATAACACCTTGAAACGCA
TTAAGAAAGAACCAGCGCTGGCTGTTGGTTTTGCAATCGCAAGAACCTATGAGCCCAATTCTGTATTTATCCTTCAAGAT
AGTCCAACTGGTGAAGAAACTACGAGCTCTAGTTCAGATAGCATGCCTGTTCCTAAAAATCAAAAAAATACTAGAGCTGG
AGATCAGCTGAGATTAGGTGCCAATACTCATGTTTTACTCTATAGTAAAAGTGGAGAGATGATTAATCCAGATACTTTTA
CTGGTTTGGCCGACCTATCATTAGACAAGGAAAAATTGGGTGAAATTAAGGAAACTACGGTTGAATCAAGTTTTGGTATG
TCTGAAGATTATCGCTATATAACGATTGGGCTGGCTACAGATGAACTAGGTTATTATTCGTCCTATGATATAAAATATGC
GACAATTTTGGTGAATGTCAGCCAAATTAAATCTTCCATTGAGAGCTATGAAGCGACAGTTGCTATTGTTATGGTATCAG
CTTGGTTGATTTCTATACTAGCAAGTATTTACCTATCGAATCTTAGCATGCGTCCAATCCTAATTAGTTATCAAAAACAA
AAAGACTTCGTTGAAAATGCTAGTCATGAGTTACGCACACCGTTGGCAGTTCTTCAAAATCGCCTGGAAAGTCTATTTCG
TCATCCCGAGACAACTATTTTGGAAAGTAGTGAAAGCATCGGATCTAGTTTAGAAGAAGTTCGAAATATGCGACTATTGA
CAACAAATTTACTTAATTTGGCTCGTCGTGATGATGGCTTAAAAGTCGATATGATCGATGTCCAACCCAACTATTTTGAT
GAAATCTTTGCTAATTACCTTATGATTGCCGAAGAAAATGGAAAAACTCTAACAGTTAATAATTTGATTCATCAGCCAAT
TCGAACAGACAAGGTTTTGATTAAACAGTTGCTCACCATTTTGTTTGACAACGCTATGAAGTATACCGATGAAGATGGGA
CAATTCAAATAGCAGCTAATATCAAGGACAAACTAGTTTGTTTTACAGTTATTGACAATGGTTTGGGAATCAGCGATACC
GATAAAAAGAAAATCTTTGATCGCTTTTACCGAGTTGACAAGGCTAGAACACGTCAAAAAGGTGGATTTGGTTTAGGTTT
ATCTTTAGCTCAACAAATTATTAAGAATTTAGATGGTGAGATTTCTGTGAGAGATAACCAACCGAAAGGAACTATTTTTG
AGGTACGTTTACCCAAATAA

Domains

Predicted by InterproScan.

• His Kinase A (phospho-acceptor) domain (HisKA) (240-306)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (350-458)

3D structure

• AlphaFold DB: A0A075SID2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaH	Streptococcus pneumoniae Rx1	49.345	99.782	0.492
ciaH	Streptococcus pneumoniae D39	49.345	99.782	0.492
ciaH	Streptococcus pneumoniae R6	49.345	99.782	0.492
ciaH	Streptococcus pneumoniae TIGR4	49.345	99.782	0.492
ciaH	Streptococcus mutans UA159	49.231	99.129	0.488