Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   NQZ93_RS00330 Genome accession   NZ_CP102141
Coordinates   54754..55653 (+) Length   299 a.a.
NCBI ID   WP_024382136.1    Uniprot ID   -
Organism   Streptococcus suis strain DNR48     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 43857..53804 54754..55653 flank 950
IScluster/Tn 56079..58880 54754..55653 flank 426


Gene organization within MGE regions


Location: 43857..58880
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NQZ93_RS00275 (NQZ93_00275) - 43857..44825 (+) 969 WP_024382139.1 hypothetical protein -
  NQZ93_RS00280 (NQZ93_00280) purB 44886..46178 (+) 1293 WP_011921659.1 adenylosuccinate lyase -
  NQZ93_RS00285 (NQZ93_00285) - 47115..47843 (+) 729 WP_024382138.1 DUF2705 family protein -
  NQZ93_RS00290 (NQZ93_00290) - 47853..48431 (+) 579 WP_011921662.1 CPBP family intramembrane glutamic endopeptidase -
  NQZ93_RS00295 (NQZ93_00295) - 48446..48874 (+) 429 WP_014636188.1 Msa family membrane protein -
  NQZ93_RS00300 (NQZ93_00300) - 48867..49739 (+) 873 WP_011921665.1 ABC transporter ATP-binding protein -
  NQZ93_RS00305 (NQZ93_00305) - 49745..50518 (+) 774 WP_012775420.1 membrane protein -
  NQZ93_RS00310 (NQZ93_00310) - 50521..52233 (+) 1713 WP_014917170.1 ABC transporter ATP-binding protein -
  NQZ93_RS00315 (NQZ93_00315) - 52335..52508 (+) 174 WP_014735240.1 hypothetical protein -
  NQZ93_RS00320 (NQZ93_00320) ruvB 52803..53804 (+) 1002 WP_024377694.1 Holliday junction branch migration DNA helicase RuvB -
  NQZ93_RS00325 (NQZ93_00325) - 53872..54507 (+) 636 WP_024382137.1 HAD-IA family hydrolase -
  NQZ93_RS00330 (NQZ93_00330) comR 54754..55653 (+) 900 WP_024382136.1 helix-turn-helix domain-containing protein Regulator
  NQZ93_RS00335 (NQZ93_00335) - 56079..57267 (+) 1189 Protein_46 IS110 family transposase -
  NQZ93_RS00340 (NQZ93_00340) - 57942..58880 (-) 939 WP_024381983.1 IS4 family transposase -

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35425.29 Da        Isoelectric Point: 4.6492

>NTDB_id=714816 NQZ93_RS00330 WP_024382136.1 54754..55653(+) (comR) [Streptococcus suis strain DNR48]
MNDKEFGQRVRQLRESASMTREQFCDDELELSVRQLTRIEAGTSKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYGNEDLAEKRDAMMTEIYDDYYDELPEEEKIAIDAIQSRIDTLESGTAGFGKEILEDYFEQIFRKRKYELND
LLIVRLHLEYVRLSSCDSEIFRQFLKIIEHLHEQINIINSNDLFVLRDTLLSCVNILGSKKYYEPISKIFDSVDKIIQST
QDFQKKPIVSVLKWKYALFVDKDRDEAEKHYLDAVLFAKLIENRELEQKIEEDWRVDNQ

Nucleotide


Download         Length: 900 bp        

>NTDB_id=714816 NQZ93_RS00330 WP_024382136.1 54754..55653(+) (comR) [Streptococcus suis strain DNR48]
ATGAACGATAAGGAATTTGGACAGCGTGTACGTCAATTACGAGAATCTGCTAGTATGACACGTGAACAGTTTTGTGACGA
TGAACTGGAACTCTCTGTGCGCCAATTAACTCGTATTGAAGCAGGTACTTCCAAGCCGACTTTTTCAAAGATTCAGTATA
TTGCAACTCGTTTAGGTATGGGACTTTACGAGCTTATGCCAGATTACGTATCCTTACCCGAAAGATATTCCAAGCTGAAG
TTTGATGTGCTTCGCACCCCAACTTATGGTAATGAAGATTTGGCGGAAAAGCGAGATGCCATGATGACAGAAATCTATGA
CGATTATTATGATGAATTGCCTGAGGAGGAGAAGATAGCAATAGATGCGATTCAATCACGAATTGATACTTTAGAGTCAG
GTACAGCAGGCTTTGGAAAAGAGATACTGGAAGACTACTTTGAACAAATTTTTCGCAAACGAAAGTATGAATTGAATGAT
TTGTTGATTGTTAGGCTCCATCTTGAATATGTTAGGTTATCTAGCTGTGATTCAGAAATATTTAGACAGTTTTTGAAAAT
TATAGAGCATTTACATGAGCAAATCAATATCATCAACTCAAATGATTTATTTGTTCTAAGGGATACATTATTATCCTGTG
TAAACATTTTGGGAAGTAAAAAATATTACGAACCAATATCAAAGATATTTGATAGTGTAGATAAGATTATACAGTCGACA
CAAGATTTTCAGAAAAAGCCCATTGTTAGTGTATTAAAATGGAAATATGCACTTTTTGTGGATAAGGATCGGGATGAGGC
TGAAAAGCATTATCTAGATGCGGTGCTATTTGCAAAATTGATAGAAAATAGAGAGTTAGAACAAAAGATTGAAGAAGATT
GGAGAGTTGACAATCAATAA

Domains

Predicted by InterproScan.

Helix-turn-helix domain (HTH_31)

(5-60)

ComR tetratricopeptide (ComR_TPR)

(73-294)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus suis P1/7

99.331

100

0.993
  comR Streptococcus suis 05ZYH33

99.331

100

0.993
  comR Streptococcus suis D9

61.462

100

0.619
  comR Streptococcus mutans UA159

43.813

100

0.438
  comR Streptococcus pyogenes MGAS315

37.374

99.331

0.371