Detailed information NTG0714803

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: NQZ94_RS08130
• Genome accession: NZ_CP102140
• Coordinates: 1614848..1615897 (-)
• Length: 349 a.a.
• NCBI ID: WP_009910567.1
• Uniprot ID: A0A7Y6RPS3
• Organism: Streptococcus suis strain DNC49
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1609848..1620897

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NQZ94_RS08110 (NQZ94_08110)	nadE	1610676..1611500 (+)	825	WP_004194617.1	ammonia-dependent NAD(+) synthetase	-
NQZ94_RS08115 (NQZ94_08115)	-	1612374..1612901 (-)	528	WP_004194600.1	VanZ family protein	-
NQZ94_RS08120 (NQZ94_08120)	rlmN	1612898..1614010 (-)	1113	WP_004194597.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
NQZ94_RS08125 (NQZ94_08125)	-	1614019..1614660 (-)	642	WP_004194595.1	YutD-like domain-containing protein	-
NQZ94_RS08130 (NQZ94_08130)	sepM	1614848..1615897 (-)	1050	WP_009910567.1	SepM family pheromone-processing serine protease	Regulator
NQZ94_RS08135 (NQZ94_08135)	coaD	1615884..1616372 (-)	489	WP_002939048.1	pantetheine-phosphate adenylyltransferase	-
NQZ94_RS08140 (NQZ94_08140)	rsmD	1616362..1616901 (-)	540	WP_009910569.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
NQZ94_RS08145 (NQZ94_08145)	-	1617200..1617922 (-)	723	WP_013730502.1	hypothetical protein	-
NQZ94_RS08150 (NQZ94_08150)	-	1617979..1618365 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
NQZ94_RS08155 (NQZ94_08155)	-	1618365..1618583 (-)	219	WP_004194736.1	YqgQ family protein	-
NQZ94_RS08160 (NQZ94_08160)	-	1618883..1619485 (-)	603	WP_004194738.1	response regulator transcription factor	-
NQZ94_RS08165 (NQZ94_08165)	-	1619482..1620576 (-)	1095	WP_024394990.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37733.77 Da
• Isoelectric Point: 4.6112

>NTDB_id=714803 NQZ94_RS08130 WP_009910567.1 1614848..1615897(-) (sepM) [Streptococcus suis strain DNC49]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLVKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSVPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=714803 NQZ94_RS08130 WP_009910567.1 1614848..1615897(-) (sepM) [Streptococcus suis strain DNC49]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAAGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAAACTTCGCAAAATATGGCGAAGTATCAAGGATTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGGTTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTATCTAATGGCAAAAACGGAATAGGCATCACTCTCGTAG
ACCATACAGAGGTTCAAAGTTCGGTTCCAATTGATTTCCAAACGGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGAATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTTATTTCGGCAGCTAAGTCAGGTGCAAGTATTTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAACCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACGAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A7Y6RPS3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.519	99.427	0.602