Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   NQZ98_RS05870 Genome accession   NZ_CP102135
Coordinates   1160979..1162358 (-) Length   459 a.a.
NCBI ID   WP_024412151.1    Uniprot ID   A0A9Q5G7Q0
Organism   Streptococcus suis strain M106471_S40     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1155979..1167358
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NQZ98_RS05850 (NQZ98_05850) - 1157238..1157828 (-) 591 WP_024400689.1 class I SAM-dependent methyltransferase -
  NQZ98_RS05855 (NQZ98_05855) coaA 1157937..1158857 (+) 921 WP_024400690.1 type I pantothenate kinase -
  NQZ98_RS05860 (NQZ98_05860) rpsT 1158916..1159164 (+) 249 WP_012027069.1 30S ribosomal protein S20 -
  NQZ98_RS05865 (NQZ98_05865) - 1159546..1160655 (-) 1110 WP_228381088.1 transglutaminase domain-containing protein -
  NQZ98_RS05870 (NQZ98_05870) ciaH 1160979..1162358 (-) 1380 WP_024412151.1 cell wall metabolism sensor histidine kinase WalK Regulator
  NQZ98_RS05875 (NQZ98_05875) ciaR 1162351..1163022 (-) 672 WP_024403127.1 response regulator transcription factor Regulator
  NQZ98_RS05880 (NQZ98_05880) - 1163216..1163596 (-) 381 WP_024403128.1 hypothetical protein -
  NQZ98_RS05885 (NQZ98_05885) phoU 1163762..1164418 (-) 657 WP_002937611.1 phosphate signaling complex protein PhoU -
  NQZ98_RS05890 (NQZ98_05890) pstB 1164447..1165205 (-) 759 WP_002937614.1 phosphate ABC transporter ATP-binding protein PstB -
  NQZ98_RS05895 (NQZ98_05895) pstB 1165217..1166020 (-) 804 WP_002940866.1 phosphate ABC transporter ATP-binding protein PstB -
  NQZ98_RS05900 (NQZ98_05900) pstA 1166045..1166932 (-) 888 WP_105106214.1 phosphate ABC transporter permease PstA -

Sequence

Protein


Download         Length: 459 a.a.        Molecular weight: 51981.71 Da        Isoelectric Point: 6.8879

>NTDB_id=714581 NQZ98_RS05870 WP_024412151.1 1160979..1162358(-) (ciaH) [Streptococcus suis strain M106471_S40]
MPKRFKKLMYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQNSDNTLKRIKKEPALAVGFAIARTYEPNSVFILQD
SPTGEETTSSSSDSMPVPKNQKNTRAGDQLRLGANTHVLLYSKSGEMINPDTFTGLADLSLDKEKLGEIKETTVESSFGM
SEDYRYITIGLATDELGYYSSYDIKYATILVNVSQIKSSIESYESTVAIVMVSAWLISILASIYLSNLSMRPILISYQKQ
KDFVENASHELRTPLAVLQNRLESLFRHPETTILESSESIGSSLEEVRNMRLLTTNLLNLARRDDGLKVDMIDVQPNYFD
EIFANYLMIAEENGKTLTVNNLIHQPIRTDKVLIKQLLTILFDNAMKYTDDDGTIQMAANIKDKLVCFTVIDNGLGISDT
DKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIIKNLDGEISVRDNQPKGTIFEVRLPK

Nucleotide


Download         Length: 1380 bp        

>NTDB_id=714581 NQZ98_RS05870 WP_024412151.1 1160979..1162358(-) (ciaH) [Streptococcus suis strain M106471_S40]
ATGCCTAAGCGATTTAAAAAATTAATGTACACGGATAAATTTTCTTTCTTTATCCGTTATTTTGCAGTATTTACTCTGAT
TTTTGGTTTAATGACAGCCATCATTTTTCAATTAATGCGTTCAACTATGTACCAAAATTCAGATAACACCTTGAAACGCA
TTAAGAAAGAACCAGCGCTGGCTGTTGGTTTTGCAATCGCAAGAACCTATGAGCCCAATTCTGTATTTATCCTTCAAGAT
AGTCCAACTGGTGAAGAAACTACGAGCTCTAGTTCAGATAGCATGCCTGTTCCTAAAAATCAAAAAAATACTAGAGCTGG
AGATCAGCTGAGATTAGGTGCCAATACTCATGTTTTACTCTATAGTAAAAGTGGAGAGATGATTAATCCAGATACTTTTA
CTGGTTTGGCCGACCTATCATTAGACAAGGAAAAATTGGGTGAAATTAAGGAAACTACGGTTGAATCAAGTTTTGGTATG
TCTGAAGATTATCGCTATATAACGATTGGGCTGGCTACAGATGAACTAGGTTATTATTCGTCCTATGATATAAAATATGC
GACAATTTTGGTGAATGTCAGCCAAATTAAATCTTCCATTGAGAGCTATGAATCGACAGTTGCTATTGTTATGGTATCAG
CTTGGTTGATTTCTATACTAGCAAGTATTTACCTATCGAATCTTAGCATGCGTCCAATCCTAATTAGTTATCAAAAACAA
AAAGACTTCGTTGAAAATGCTAGTCATGAGTTACGCACACCGTTGGCAGTTCTTCAAAATCGCCTGGAAAGTCTATTTCG
TCATCCCGAGACAACTATTTTGGAAAGTAGTGAAAGCATCGGATCTAGTTTAGAAGAAGTCCGAAATATGCGCTTATTGA
CAACGAACTTGCTCAATTTGGCTCGCCGTGATGATGGCTTAAAAGTTGATATGATCGATGTCCAACCCAACTATTTTGAT
GAAATCTTTGCTAATTACCTTATGATTGCCGAAGAAAATGGAAAAACTCTAACAGTTAATAATTTGATTCATCAGCCAAT
TCGAACAGACAAAGTTTTGATTAAACAGTTGCTCACCATTTTGTTTGACAACGCTATGAAGTATACCGATGATGATGGGA
CAATTCAAATGGCAGCTAATATCAAGGATAAACTAGTTTGTTTTACAGTTATTGACAATGGTTTGGGAATCAGCGATACC
GATAAAAAGAAAATCTTTGATCGCTTTTACCGAGTTGACAAGGCTAGAACACGTCAAAAAGGTGGATTTGGTTTAGGTTT
ATCTTTAGCTCAACAAATTATTAAGAATCTAGATGGTGAGATTTCTGTGAGAGATAACCAACCGAAAGGAACTATTTTTG
AGGTACGATTACCCAAATAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(350-458)

His Kinase A (phospho-acceptor) domain (HisKA)

(240-306)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

49.127

99.782

0.49
  ciaH Streptococcus pneumoniae D39

49.127

99.782

0.49
  ciaH Streptococcus pneumoniae R6

49.127

99.782

0.49
  ciaH Streptococcus pneumoniae TIGR4

49.127

99.782

0.49
  ciaH Streptococcus mutans UA159

49.231

99.129

0.488