Detailed information NTG0713965

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: NQD66_RS04325
• Genome accession: NZ_CP101995
• Coordinates: 789934..792171 (+)
• Length: 745 a.a.
• NCBI ID: WP_000902956.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain BCJB2983
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 784934..797171

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NQD66_RS04300 (NQD66_04295)	-	785530..787116 (+)	1587	WP_000673086.1	DEAD/DEAH box helicase	-
NQD66_RS04305 (NQD66_04300)	-	787299..787565 (-)	267	WP_000598735.1	GIY-YIG nuclease family protein	-
NQD66_RS04310 (NQD66_04305)	-	787558..788322 (-)	765	WP_000567428.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
NQD66_RS04315 (NQD66_04310)	-	788457..789197 (+)	741	WP_000500222.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
NQD66_RS04320 (NQD66_04315)	-	789297..789950 (+)	654	WP_000461741.1	helix-hairpin-helix domain-containing protein	-
NQD66_RS04325 (NQD66_04320)	comEC/celB	789934..792171 (+)	2238	WP_000902956.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
NQD66_RS04330 (NQD66_04325)	-	792297..793106 (+)	810	WP_000153219.1	Cof-type HAD-IIB family hydrolase	-
NQD66_RS04335 (NQD66_04330)	-	793117..794061 (+)	945	WP_000200834.1	LacI family DNA-binding transcriptional regulator	-
NQD66_RS04340 (NQD66_04335)	-	794120..795112 (-)	993	WP_000800989.1	alpha/beta hydrolase fold domain-containing protein	-
NQD66_RS04345 (NQD66_04340)	-	795288..796016 (+)	729	WP_000468967.1	methyltransferase domain-containing protein	-
NQD66_RS04350 (NQD66_04345)	holA	796070..797107 (+)	1038	WP_000560298.1	DNA polymerase III subunit delta	-

Sequence

Protein

• Length: 745 a.a.
• Molecular weight: 85666.56 Da
• Isoelectric Point: 9.8125

>NTDB_id=713965 NQD66_RS04325 WP_000902956.1 789934..792171(+) (comEC/celB) [Streptococcus agalactiae strain BCJB2983]
MLHLTKYFPLKPIYLALLVFQIYLLVFSWTMLGCAFLLFTFIFLIYQYDRETIFKTITIVIFFLFYFLWQNHNMNVQYQR
VPNHISQIKVRIDTISINGDVLSFQADASGNTYQAFYTLKNKSEKDYFQNLDNNIMIIADIKLEEAEERRHFNGFDYRQY
LKRHGIYRIAKVTKIKQIRLFQHRSFFDLMFKWRRSAIVISQTFPNPMRHYMSGLLFGYLDKTFDDMSDLYSSLGIIHLF
ALSGMQVGFFLGIFRYICLRIGLRLDHVWLLQIPFSLIYAGLTGFSISVVRALIQSLLSHSGVKKDENFALCLLICLISL
PHSLLTTGGVLSFAYAFILTMTSFDHFSSIKKVAIESLTVSVGILPILTYYFSGFQPISIILTALLSFAFDIIFLPLLTV
IFVLSPFVKLSCINSLFEILEVLLKWTGQLFPRPLIFGKPSLFLLIVMIIILGLLYDYYHSKCFRYCSLLIIFTLFFITK
NPITNEVAILDVGQGDSILVRDWLGKTILIDTGGRVRFEQPEEWKQKVNQSNAERTLIPYLKSRGISKIDNLVITHTDTD
HMGDMEVISKHFKVARLITSSGSLTNSQYVKRLSKIGVAVKSIEAGDKLSVMGSYLQVLYPWHKGDGKNNDSIVLYGHLL
GKGFLFTGDLEEEGEKQLLEAYPNLSVDILKAGHHGSKGSSSLSFLKKLSPSVVLVSAGKNNRYQHPHQETLQRFQKIKS
KIFRTDQSGTIRLTGWWKWHIQTVR

Nucleotide

• Length: 2238 bp

>NTDB_id=713965 NQD66_RS04325 WP_000902956.1 789934..792171(+) (comEC/celB) [Streptococcus agalactiae strain BCJB2983]
ATGTTACACTTGACTAAGTATTTTCCTCTAAAACCTATTTATTTAGCATTGTTGGTCTTCCAAATTTACTTACTAGTGTT
TTCTTGGACAATGCTTGGTTGTGCCTTTCTTTTATTTACTTTTATTTTTCTGATTTATCAATATGATCGTGAAACTATTT
TTAAAACAATAACAATAGTAATTTTTTTCTTATTTTATTTTTTATGGCAAAATCACAATATGAATGTCCAATATCAAAGA
GTACCGAATCATATTAGCCAGATTAAAGTGCGTATTGATACTATTTCTATCAATGGTGATGTTTTATCATTCCAGGCAGA
TGCTTCAGGTAACACTTATCAAGCTTTTTACACATTAAAAAATAAAAGTGAGAAAGATTATTTTCAAAATCTTGATAATA
ATATAATGATAATTGCAGATATCAAACTTGAAGAAGCAGAGGAGAGAAGGCATTTTAATGGCTTTGATTATCGTCAGTAT
TTAAAAAGACATGGAATTTATCGTATCGCCAAAGTGACAAAGATAAAACAGATACGCTTATTTCAACATAGGTCTTTCTT
TGATCTTATGTTTAAGTGGCGTAGAAGTGCAATTGTTATTAGTCAAACTTTTCCAAATCCTATGCGTCACTATATGTCAG
GGCTTTTGTTTGGATATCTAGATAAGACCTTTGATGACATGTCCGATTTATATAGTAGTCTAGGTATTATACATTTATTT
GCTTTGTCAGGTATGCAAGTAGGTTTTTTTCTCGGTATTTTTCGTTATATCTGTCTACGTATTGGCTTACGTCTAGACCA
TGTTTGGTTACTTCAAATACCATTCTCGCTAATTTATGCTGGTTTAACAGGCTTTAGTATCTCAGTCGTTAGGGCACTTA
TTCAATCTTTATTATCACATAGCGGTGTCAAGAAAGATGAGAACTTTGCTCTCTGCTTGTTAATTTGTCTTATCTCTCTC
CCCCACTCACTTTTGACTACGGGAGGAGTTCTTAGCTTTGCTTATGCTTTTATACTTACGATGACCTCCTTTGATCATTT
TTCGAGTATAAAAAAAGTAGCTATCGAATCTTTGACAGTCTCTGTAGGAATTCTTCCCATACTAACCTACTATTTTTCGG
GTTTTCAACCAATATCAATTATATTAACAGCACTTTTATCTTTTGCATTTGATATTATATTTTTGCCTTTATTAACTGTT
ATATTTGTCTTATCACCGTTCGTTAAATTAAGTTGTATTAATAGTTTGTTTGAAATCCTAGAAGTATTATTAAAATGGAC
TGGGCAACTGTTTCCAAGACCACTTATTTTTGGAAAGCCCAGCCTTTTTCTTTTAATAGTCATGATTATAATTTTGGGAT
TACTTTATGATTATTATCATTCTAAATGTTTTCGTTATTGCTCCCTTCTTATTATCTTTACCTTGTTTTTTATCACTAAG
AATCCAATTACTAACGAGGTTGCGATTTTAGATGTTGGACAAGGAGATAGTATTTTAGTGAGGGATTGGTTAGGAAAAAC
AATTTTAATTGATACTGGGGGAAGGGTGAGATTTGAACAGCCTGAAGAATGGAAACAAAAAGTAAACCAGTCTAATGCTG
AGAGAACGCTCATTCCTTACTTGAAAAGCAGAGGTATTAGCAAGATAGATAATTTAGTGATAACTCATACCGATACAGAT
CATATGGGGGATATGGAAGTTATCTCAAAGCATTTTAAAGTTGCACGTTTGATTACAAGTTCAGGTTCTTTAACGAATTC
GCAGTACGTTAAGCGTTTATCAAAGATAGGAGTAGCTGTAAAATCTATAGAAGCTGGTGATAAACTTTCTGTCATGGGAA
GTTATTTACAAGTACTTTACCCATGGCACAAGGGTGATGGAAAAAATAATGATTCAATTGTTTTATATGGACATTTATTA
GGAAAAGGCTTCTTATTTACCGGTGATTTGGAGGAAGAGGGAGAAAAGCAGTTATTAGAAGCTTATCCTAATTTATCAGT
AGATATCCTTAAAGCAGGACATCATGGTTCTAAGGGCTCATCAAGTCTATCCTTTCTGAAAAAGTTGTCTCCTAGTGTGG
TTCTAGTGTCAGCTGGTAAAAATAATCGTTACCAGCATCCTCATCAAGAGACTTTACAAAGGTTCCAAAAGATTAAAAGC
AAGATTTTCCGAACGGATCAATCAGGTACAATTAGGCTAACAGGATGGTGGAAGTGGCATATTCAGACAGTTCGTTGA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (215-458)

• Metallo-beta-lactamase superfamily (Lactamase_B) (491-576)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	48.262	100	0.485
comEC/celB	Streptococcus mitis NCTC 12261	48.193	100	0.483
comEC/celB	Streptococcus pneumoniae TIGR4	46.791	100	0.47
comEC/celB	Streptococcus pneumoniae Rx1	46.319	100	0.464
comEC/celB	Streptococcus pneumoniae D39	46.319	100	0.464
comEC/celB	Streptococcus pneumoniae R6	46.319	100	0.464
comEC	Lactococcus lactis subsp. cremoris KW2	44.355	99.866	0.443