Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYE   Type   Machinery gene
Locus tag   NPS16_RS09035 Genome accession   NZ_CP101986
Coordinates   1901660..1901953 (-) Length   97 a.a.
NCBI ID   WP_258968995.1    Uniprot ID   -
Organism   Streptococcus mutans strain COCC33-14     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1896660..1906953
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NPS16_RS09000 (NPS16_09000) - 1896684..1897346 (-) 663 WP_002263446.1 type II CAAX endopeptidase family protein -
  NPS16_RS09005 (NPS16_09005) - 1897399..1897839 (-) 441 WP_002263445.1 hypothetical protein -
  NPS16_RS09010 (NPS16_09010) - 1897808..1898053 (-) 246 WP_002263444.1 helix-turn-helix transcriptional regulator -
  NPS16_RS09015 (NPS16_09015) - 1898606..1899805 (-) 1200 WP_002265895.1 acetate kinase -
  NPS16_RS09020 (NPS16_09020) comYH 1899864..1900817 (-) 954 WP_019317550.1 class I SAM-dependent methyltransferase Machinery gene
  NPS16_RS09025 (NPS16_09025) comYG 1900872..1901261 (-) 390 WP_002263441.1 competence type IV pilus minor pilin ComGG Machinery gene
  NPS16_RS09030 (NPS16_09030) comYF 1901239..1901673 (-) 435 WP_002263440.1 competence type IV pilus minor pilin ComGF Machinery gene
  NPS16_RS09035 (NPS16_09035) comYE 1901660..1901953 (-) 294 WP_258968995.1 competence type IV pilus minor pilin ComGE Machinery gene
  NPS16_RS09040 (NPS16_09040) comYD 1901925..1902329 (-) 405 WP_168742475.1 competence type IV pilus minor pilin ComGD Machinery gene
  NPS16_RS09045 (NPS16_09045) comYC 1902316..1902630 (-) 315 WP_002263437.1 competence type IV pilus major pilin ComGC Machinery gene
  NPS16_RS09050 (NPS16_09050) comYB 1902630..1903661 (-) 1032 WP_258969313.1 competence type IV pilus assembly protein ComGB Machinery gene
  NPS16_RS09055 (NPS16_09055) comYA 1903597..1904538 (-) 942 WP_002263435.1 competence type IV pilus ATPase ComGA Machinery gene
  NPS16_RS09060 (NPS16_09060) - 1904669..1905052 (-) 384 WP_002263434.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 11010.92 Da        Isoelectric Point: 9.4913

>NTDB_id=713679 NPS16_RS09035 WP_258968995.1 1901660..1901953(-) (comYE) [Streptococcus mutans strain COCC33-14]
MVSIKKQKVKAYILLESLVALGLFVTITTLILTQLSHYQERTAKNLQKQEILNLAIMALHTQQDHLSFNGVSVTVVKNQG
ETIVYHDHEEVINLVKK

Nucleotide


Download         Length: 294 bp        

>NTDB_id=713679 NPS16_RS09035 WP_258968995.1 1901660..1901953(-) (comYE) [Streptococcus mutans strain COCC33-14]
GTGGTCAGTATAAAAAAACAGAAAGTTAAAGCTTATATTCTTCTAGAAAGTTTAGTTGCTTTGGGGCTTTTCGTAACCAT
CACAACTTTAATTCTTACTCAGTTGAGTCATTATCAGGAAAGAACAGCTAAAAATTTACAAAAACAAGAAATATTGAATT
TAGCAATAATGGCTCTTCATACTCAGCAAGATCATTTAAGCTTCAACGGCGTCAGTGTTACGGTTGTTAAAAATCAAGGG
GAAACTATAGTTTATCATGATCATGAGGAGGTTATCAATCTTGTTAAAAAGTAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYE Streptococcus mutans UA140

98.969

100

0.99
  comYE Streptococcus mutans UA159

98.969

100

0.99
  comGE/cglE Streptococcus pneumoniae Rx1

43.333

92.784

0.402
  comGE/cglE Streptococcus pneumoniae D39

43.333

92.784

0.402
  comGE/cglE Streptococcus pneumoniae R6

43.333

92.784

0.402
  comGE/cglE Streptococcus pneumoniae TIGR4

43.333

92.784

0.402
  comGE/cglE Streptococcus mitis NCTC 12261

43.333

92.784

0.402
  comGE/cglE Streptococcus mitis SK321

43.333

92.784

0.402