Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   K6J59_RS03760 Genome accession   NZ_AP018782
Coordinates   750882..752102 (+) Length   406 a.a.
NCBI ID   WP_005666687.1    Uniprot ID   -
Organism   Haemophilus influenzae strain CHBN-V-2 isolate 13H37     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 745882..757102
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6J59_RS03740 (CHBNV2_07080) corC 746848..747747 (-) 900 WP_005648977.1 CNNM family magnesium/cobalt transport protein CorC -
  K6J59_RS03745 (CHBNV2_07090) ampD 748379..748930 (-) 552 WP_005666680.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  K6J59_RS03750 (CHBNV2_07100) pilA 749045..749494 (+) 450 WP_005666683.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  K6J59_RS03755 (CHBNV2_07110) pilB 749491..750885 (+) 1395 WP_005666685.1 GspE/PulE family protein Machinery gene
  K6J59_RS03760 (CHBNV2_07120) pilC 750882..752102 (+) 1221 WP_005666687.1 type II secretion system F family protein Machinery gene
  K6J59_RS03765 (CHBNV2_07130) pilD 752099..752791 (+) 693 WP_005666688.1 A24 family peptidase Machinery gene
  K6J59_RS03770 (CHBNV2_07140) rho 752846..754108 (-) 1263 WP_005666690.1 transcription termination factor Rho -
  K6J59_RS03775 (CHBNV2_07150) metJ 754355..754672 (+) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  K6J59_RS03780 (CHBNV2_07160) cueR 754686..755072 (-) 387 WP_005648963.1 Cu(I)-responsive transcriptional regulator -
  K6J59_RS03785 (CHBNV2_07170) - 755149..755355 (+) 207 WP_005666692.1 heavy-metal-associated domain-containing protein -
  K6J59_RS03790 (CHBNV2_07180) - 755441..755647 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  K6J59_RS03795 (CHBNV2_07190) - 755721..755927 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -

Sequence

Protein


Download         Length: 406 a.a.        Molecular weight: 46207.43 Da        Isoelectric Point: 9.8218

>NTDB_id=71360 K6J59_RS03760 WP_005666687.1 750882..752102(+) (pilC) [Haemophilus influenzae strain CHBN-V-2 isolate 13H37]
MTKKLFYYQGSNALNQKQKGSIIADTKQQAHFQLISRGLTHIKLQQNWQFGAKPKNSEISELLNQLATLLQSVIPLKNSL
QILQQNCTQIMLNEWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLAVVCKKIATHRSQSLALQRKLQK
IMVYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFALSFVLFYYFYLKRQIWF
HQQKNQLISVTPIFGTIQKLSRLVNFSRSLQIMLQAGVPLNQALDSFLPRTQTWQTKKTLVNDIVLDKEVRSILQWVSQG
YAFSDSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIADNYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFN
MGSVIQ

Nucleotide


Download         Length: 1221 bp        

>NTDB_id=71360 K6J59_RS03760 WP_005666687.1 750882..752102(+) (pilC) [Haemophilus influenzae strain CHBN-V-2 isolate 13H37]
ATGACTAAAAAACTCTTTTATTATCAAGGTAGTAACGCATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACAAA
ACAACAAGCGCACTTTCAATTAATAAGCCGCGGGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAGC
CCAAAAATTCAGAAATCAGTGAATTACTCAATCAATTAGCGACATTGCTACAGTCCGTAATTCCGTTAAAAAACAGCCTG
CAAATTTTGCAACAAAATTGTACTCAAATTATGCTCAACGAATGGCTTGAACGACTGCTTCAATCCATTGAATCTGGCTT
AGCATTCTCACAAGCAATTGAACAACAAGGAAAATATCTCACACAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CAGGAAAACTTGCCGTAGTTTGTAAAAAAATAGCCACGCACCGTAGCCAATCTTTGGCTTTACAACGCAAATTACAGAAA
ATTATGGTATATCCCTCAATGGTATTGGGAATTTCTCTATTATTGACACTCGCATTACTGCTTTTTATCGTGCCTCAATT
TGCTGAAATGTACAGTGGCAATAATGCCGAATTACCAACAATAACCGCAATATTGCTCTCCATATCCAATTTTCTTAAGC
AAAATATTGGCATTTTGTTATTTTTCGCTTTGAGTTTTGTTCTATTTTATTACTTCTATCTAAAACGCCAGATCTGGTTT
CATCAACAGAAAAACCAACTTATCTCTGTCACGCCTATTTTTGGCACAATTCAAAAACTTTCACGTTTAGTGAACTTTAG
TCGCAGTTTACAAATTATGTTGCAGGCTGGCGTACCGCTTAATCAGGCACTAGACAGTTTTCTTCCTCGCACACAAACGT
GGCAAACCAAGAAAACGCTTGTAAATGACATCGTATTAGATAAAGAAGTGCGGTCAATTTTACAATGGGTTTCTCAAGGC
TATGCGTTTTCTGATAGTGTAAGTAGCGATCTTTTCCCGATGGAAGCACAACAAATGCTCCAAATTGGCGAACAAAGCGG
AAAACTCGCTTTGATGCTAGAGCATATTGCGGATAATTACCAAGAAAAACTTAATCATCAAATTGACTTACTCTCACAAA
TGCTAGAACCATTAATGATGGTAATTATCGGCAGTTTGATTGGAATTATTATGATGGGAATGTATTTACCTATCTTTAAT
ATGGGCTCTGTTATTCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(266-397)

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae 86-028NP

97.291

100

0.973
  pilC Haemophilus influenzae Rd KW20

96.552

100

0.966
  pilC Glaesserella parasuis strain SC1401

38.404

98.768

0.379

Multiple sequence alignment